1. Facile preparation of ammonium alginate-derived nanofibers carrying diverse therapeutic cargo
- Author
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Thushara J. Athauda, Justin M. Chalker, Ruya R. Ozer, Caitlin E. Pegg, and Gregory H. Jones
- Subjects
Models, Molecular ,Alginates ,Nanofibers ,Catalysis ,chemistry.chemical_compound ,Drug Delivery Systems ,Glucuronic Acid ,Ammonium Compounds ,Polymer chemistry ,Materials Chemistry ,Alginic acid ,Wound Healing ,Ion exchange ,Hexuronic Acids ,Metals and Alloys ,General Chemistry ,AMMONIUM ALGINATE ,Glucuronic acid ,Combinatorial chemistry ,Ammonium compounds ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,chemistry ,Nanofiber ,Ceramics and Composites ,Functional polymers - Abstract
Alginic acid was converted to a variety of ammonium alginate derivatives carrying diverse chemical cargo such as analgesics, antibiotics, and enzymes. These functional polymers could be fashioned into nanofibrous mats by electrostatic spinning. The therapeutic payload could be released in functional form by a simple ion exchange mechanism. Prospects in wound healing are discussed.
- Published
- 2014
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