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Start Over Author "Tokunaga, Kento" Publisher royal society of chemistry
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1. 1,3-Butadiynyl sulfide-based compact trialkyne platform molecule for sequential assembly of three azides.

Author

Taguchi, Jumpei, Tokunaga, Kento, Tabuchi, Hitomi, Nishiyama, Takashi, Kii, Isao, and Hosoya, Takamitsu

Subjects
*TRIAZOLES, *AZIDES, *MOIETIES (Chemistry), *SULFIDES, *MOLECULES
Abstract

A compact trialkyne platform with a silyl-protected 1,3-butadiynyl sulfide moiety and a terminal alkyne group has been developed for sequential regioselective transition metal-catalyzed triazole formation reactions with three azides. This method enabled the facile construction of a low-molecular-weight triazole library and the synthesis of middle-molecular-weight trifunctional probes for protein modification. [ABSTRACT FROM AUTHOR]

Published
2024
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