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Your search keyword '"Rong, Jiaxin"' showing total 2 results
Start Over Author "Rong, Jiaxin" Publisher royal society of chemistry
2 results on '"Rong, Jiaxin"'

2. Metal-free synthesis of gem-difluorinated heterocycles from enaminones and difluorocarbene precursors.

Author

Wang, Fei, Fu, Rui, Chen, Jie, Rong, Jiaxin, Wang, Enfu, Zhang, Jian, Zhang, Zhengyu, and Jiang, Yaojia

Subjects
HETEROCYCLIC compounds, CYCLOPROPANATION, FUNCTIONAL groups
Abstract

A cascade strategy to synthesise gem-difluorinated 2H-furans from reactions of BrCF2CO2Et with enaminones has been described. The reactions tolerate a wide variety of functional groups under metal-free conditions. An active aminocyclopropane is proposed to be a key intermediate through the cyclopropanation of difluorocarbene with enaminones, which further triggers a regioselective C–C bond cleavage in situ to afford the corresponding gem-difluorinated 2H-furans. [ABSTRACT FROM AUTHOR]

Published
2022
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