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Your search keyword '"Pattanayak MR"' showing total 2 results
Start Over Author "Pattanayak MR" Publisher royal society of chemistry
2 results on '"Pattanayak MR"'

1. Sydnone-based turn-on fluorogenic probes for no-wash protein labeling and in-cell imaging.

Author

Plougastel L, Pattanayak MR, Riomet M, Bregant S, Sallustrau A, Nothisen M, Wagner A, Audisio D, and Taran F

Subjects
Alkynes chemistry, Cycloaddition Reaction, Electrophoresis, Polyacrylamide Gel, HeLa Cells, Humans, Microscopy, Confocal, Proteins metabolism, Fluorescent Dyes chemistry, Proteins chemistry, Sydnones chemistry
Abstract

We report the synthesis and use of sydnone-based profluorophores as tools for imaging applications. These new probes display exquisite reactivity towards strain promoted cycloaddition reactions with cycloalkynes allowing fast, efficient and selective labeling in biological media. Styryl-pyridinium sydnone probes were found particularly interesting for click reactions to proceed selectively inside cells.

Published
2019
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2. Ring-closing metathesis (RCM) based synthesis of the macrolactone core of amphidinolactone A.

Author

Mohapatra DK, Pattanayak MR, Das PP, Pradhan TR, and Yadav JS

Subjects
Cyclization, Cytotoxins chemical synthesis, Models, Molecular, Dinoflagellida chemistry, Macrolides chemical synthesis
Abstract

A convergent synthesis of the macrolactone core of amphidinolactone A has been achieved, in a 10 step linear sequence with 32% overall yield, through a ring-closing metathesis reaction as the macrolactonization step. The RCM precursor was obtained by the union of acid and alcohol fragments derived from (R)-epichlorohydrin and (R)-2,3-O-isopropylidene glyceraldehyde, respectively.

Published
2011
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