Search

Your search keyword '"Li, Xueyu"' showing total 2 results
Start Over Author "Li, Xueyu" Publisher royal society of chemistry
2 results on '"Li, Xueyu"'

1. Transition-metal-free azide insertion of N-triftosylhydrazones using a non-metallic azide source.

Author

Li, Xueyu, Song, Jin-Na, Karmakar, Swastik, Lu, Ying, Lv, Ye, Liao, Peiqiu, and Liu, Zhaohong

Subjects
*FUNCTIONAL groups, *AZIDATION, *AZIDES, *NITROGEN, *MOLECULES, *IONS, *TRANSITION metals
Abstract

Benzylic azides, an important class of active organic synthons, were synthesized in high yields from the easily accessible N-triftosylhydrazones with stable TMSN3 under mild conditions. The reaction features high efficiency and excellent functional group tolerance, as illustrated by gram-scale synthesis and the synthesis of drug-like molecules. Mechanistic studies reveal that azidation occurs at the electron-deficient diazo-carbon via the elimination of N2 by an azide ion. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results