Search

Your search keyword '"Leong, Cheryl"' showing total 2 results
Start Over Author "Leong, Cheryl" Publisher royal society of chemistry
2 results on '"Leong, Cheryl"'

1. Microglia specific fluorescent probes for live cell imaging.

Author

Leong, Cheryl, Lee, Sung Chan, Ock, Jiyeon, Li, Xin, See, Peter, Park, Sung Jin, Ginhoux, Florent, Yun, Seong-Wook, and Chang, Young-Tae

Subjects
*MICROGLIA, *CELL imaging, *SMALL molecules, *IMMUNOGLOBULINS, *FLUORESCENT proteins, *NEUROLOGICAL disorders
Abstract

Small molecule fluorescent probes offer significant advantages over conventional antibody and fluorescent protein labeling techniques. Here we present CDr10a and CDr10b, dyes that label live microglia specifically. They may be applied to the isolation and imaging of live microglia when investigating their role in neuroinflammatory diseases. [ABSTRACT FROM AUTHOR]

Published
2014
Full Text
View/download PDF

2. A fluorescent probe for imaging symmetric and asymmetric cell division in neurosphere formation.

Author

Yun SW, Leong C, Bi X, Ha HH, Yu YH, Tan YL, Narayanan G, Sankaran S, Kim JY, Hariharan S, Ahmed S, and Chang YT

Subjects
Animals, Cells, Cultured, Mice, Neural Stem Cells physiology, Asymmetric Cell Division physiology, Fluorescent Dyes chemistry, Neural Stem Cells chemistry, Time-Lapse Imaging methods
Abstract

We report here a novel fluorescent chemical probe which stains distinct neural stem/progenitor cells (NSPCs) by binding to acid ceramidase in mouse neurospheres. is distributed evenly or unevenly to the daughter cells during multiple mitoses enabling the live imaging of symmetric and asymmetric divisions of isolated NSPCs.

Published
2014
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results