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Your search keyword '"Kundu, Moumita"' showing total 2 results
Start Over Author "Kundu, Moumita" Publisher royal society of chemistry
2 results on '"Kundu, Moumita"'

1. A two-photon responsive naphthyl tagged p-hydroxyphenacyl based drug delivery system: uncaging of anti-cancer drug in the phototherapeutic window with real-time monitoring.

Author

Singh, Amit Kumar, Kundu, Moumita, Roy, Samrat, Roy, Biswajit, Shah, Sk. Sheriff, Nair, Asha V, Pal, Bipul, Mondal, Mahitosh, and Singh, N. D. Pradeep

Subjects
*DRUG delivery systems, *DRUG monitoring
Abstract

We report a two-photon responsive drug delivery system (DDS), namely, p-hydroxyphenacyl–naphthalene–chlorambucil (pHP–Naph–Cbl), having a two-photon absorption (TPA) cross-section of ≥20 GM in the phototherapeutic window (700 nm). Our DDS exhibited both AIE and ESIPT phenomena, which were utilized for the real-time monitoring of anti-cancer drug release. [ABSTRACT FROM AUTHOR]

Published
2020
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2. Stepwise dual stimuli triggered dual drug release by a single naphthalene based two-photon chromophore to reverse MDR for alkylating agents with dual surveillance in uncaging steps.

Author

Roy, Biswajit, Kundu, Moumita, Singh, Amit Kumar, Singha, Tara, Bhattacharya, Sayantan, Datta, Prasanta Kumar, Mandal, Mahitosh, and Singh, N. D. Pradeep

Subjects
*ALKYLATING agents, *NAPHTHALENE, *TREATMENT effectiveness, *DRUG utilization, *ANTINEOPLASTIC agents, *NANOCARRIERS
Abstract

In this work, we depleted glutathione (GSH) by releasing SO2 with internal stimulus GSH itself, and also selectively marked the cancer cells followed by release of anticancer drug using another orthogonal stimulus i.e., two-photon (TP) NIR light by a single naphthalene based chromophore (TP absorbance 77 GM and uncaging cross-section 21 GM). We demonstrated the improved therapeutic efficacy of chlorambucil by the stepwise dual stimuli approach and dual surveillance of both the drug uncaging process in real-time using in vitro studies. [ABSTRACT FROM AUTHOR]

Published
2019
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