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Your search keyword '"Kitamatsu, Mizuki"' showing total 8 results
Start Over Author "Kitamatsu, Mizuki" Publisher royal society of chemistry
8 results on '"Kitamatsu, Mizuki"'

7. A novel method for screening peptides that bind to proteins by using multiple fluorescent amino acids as fluorescent tags.

Author

Kitamatsu, Mizuki, Futami, Midori, and Sisido, Masahiko

Subjects
*PEPTIDES, *PROTEINS, *FLUORESCEIN, *AMINO acids, *BIOMOLECULES
Abstract

We describe a new screening method for simultaneously detecting peptides that bind to a target protein by fluorescence obtained from fluorescent amino acid-modified peptides. [ABSTRACT FROM AUTHOR]

Published
2010
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8. Oxy-peptide nucleic acid with a pyrrolidine ring that is configurationally optimized for hybridization with DNA.

Author

Kitamatsu M, Shigeyasu M, Okada T, and Sisido M

Subjects
DNA chemistry, Molecular Conformation, Nucleic Acids chemistry, Nucleic Acids metabolism, Peptide Fragments chemistry, Pyrrolidines chemistry, DNA metabolism, Hybridization, Genetic physiology, Peptide Fragments metabolism, Pyrrolidines metabolism
Abstract

Four stereoisomers of oxy-peptide nucleic acids containing ether linkages in the main chain and conformationally-restricted pyrrolidine rings (pyrrolidine-based oxy-PNA = POPNA) were newly synthesized and investigated for binding to DNA. cis-l-POPNA with 9 adenine bases formed the most stable hybrid with dT(9). The POPNA showed high sequence specificity similar to that of the Nielsen-type PNA and sharper melting behavior in hybridization with DNA than the Nielsen-type PNA.

Published
2004
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