Search

Your search keyword '"Kang, Wenyuan"' showing total 1 results
Start Over Author "Kang, Wenyuan" Publisher royal society of chemistry

Refine your results

1 results on '"Kang, Wenyuan"'

1. Charge designable and tunable GFP as a target pH-responsive carrier for intracellular functional protein delivery and tracing.

Author

Hu, Shanfang, Chen, Xiaoye, Lei, Chunyang, Tang, Rui, Kang, Wenyuan, Deng, Honghua, Huang, Yan, Nie, Zhou, and Yao, Shouzhuo

Subjects
*GREEN fluorescent protein, *INTRACELLULAR tracking, *PH effect, *INHIBITION of cellular proliferation, *HELA cells
Abstract

A charge designable and tunable green fluorescent protein (GFP)-based protein delivery strategy was proposed. The acquired His29GFP selectively permeates the cell membrane at a target pH of 6.5 and escapes from the endosome efficiently. The delivered RNase A caused substantial mRNA degradation in HeLa cells, and proliferation inhibition in different cell lines and a 3D tumor model at pH 6.5. [ABSTRACT FROM AUTHOR]

Published
2018
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results