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1. Use of a redox probe for an electrochemical RNA-ligand binding assay in microliter droplets.

Author

Guyon H, Mavré F, Catala M, Turcaud S, Brachet F, Limoges B, Tisné C, and Micouin L

Subjects
Binding Sites, Ligands, Oxidation-Reduction, Particle Size, Surface Properties, Aptamers, Nucleotide chemistry, Electrochemical Techniques, RNA chemistry, Small Molecule Libraries chemistry
Abstract

In this work, we report an affordable, sensitive, fast and user-friendly electroanalytical method for monitoring the binding between unlabeled RNA and small compounds in microliter-size droplets using a redox-probe and disposable miniaturized screen-printed electrochemical cells.

Published
2017
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