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The article analyzes the recent data concerning the new trends in the treatment of acne vulgaris of moderate severity using tetracyclines. Low-dose regimen of doxycycline is highly effective against inflammatory and noninflammatory lesions in patients with moderate acne on the face with a minority of side effects.

The article describes the results of a study conducted in 1994-2005 by the immune-enzyme assay method. The study involved 1,014 subjects aged 14-64 and randomly selected from the population of Novosibirsk and rural regions of Tyva and Mountain Altai based on determination of G-class antibodies to HSV-1 and HSV-2 by the IEA method. The prevalence rate for anti-HSV-1 antibodies did not differ in the study populations and was 99.4%. The general prevalence rate of anti-HSV-2 antibodies was higher in women vs. men and did not differ in different regions. The frequency of cases when HSV-2 was diagnosed was growing in proportion to the age from 1.0% in teenagers aged 14-17 up to 19.4-37.5% in subjects aged 55-64. The prevalence of HSV-2 in Siberia was found to be similar to that in the United States and Scandinavian countries. The sexual profile of subjects infected with HSV-2 in Russia did not differ from that in other population-based studies conducted in the world.