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Dermatofibroma (benign fibrous histiocytoma) represents one of the most common skin tumors. We present the case of a 52 year old female patient with a highly pigmented nodular lesion, localized on the right thigh. Dermoscopy completed the clinical diagnosis, but could not exclude a malignant tumour . Ultrasound examination (Dermascan C sonograms 20 MHz, 2D ultrasound, Doppler ultrasound, contrast enhanced ultrasound, and elastography) evidenced a highly vascularized lesion (peripheral type of vascularization), and a sonographic depth index of 8.3 mm. The histopathological examination confirmed the diagnosis of a benign fibrous histiocytoma with the histological Breslow index of 8 mm. The particularity of the case consists of the complex non-invasive and in real time imaging examination which describes the "in vivo" histology of the benign tumor lesion. [ABSTRACT FROM AUTHOR]

Dermatofibroma (benign fibrous histiocytoma) represents one of the most common skin tumors. We present the case of a 52 year old female patient with a highly pigmented nodular lesion, localized on the right thigh. Dermoscopy completed the clinical diagnosis, but could not exclude a malignant tumour . Ultrasound examination (Dermascan C sonograms 20 MHz, 2D ultrasound, Doppler ultrasound, contrast enhanced ultrasound, and elastography) evidenced a highly vascularized lesion (peripheral type of vascularization), and a sonographic depth index of 8.3 mm. The histopathological examination confirmed the diagnosis of a benign fibrous histiocytoma with the histological Breslow index of 8 mm. The particularity of the case consists of the complex non-invasive and in real time imaging examination which describes the "in vivo" histology of the benign tumor lesion. [ABSTRACT FROM AUTHOR]