1. Abp1p and cortactin, new 'hand-holds' for actin
- Author
-
Laura M. Machesky and Isabel M. Olazabal
- Subjects
Saccharomyces cerevisiae Proteins ,Reviews ,Arp2/3 complex ,macromolecular substances ,Models, Biological ,Fungal Proteins ,Actin-binding protein ,Mini-Reviews ,biology ,Microfilament Proteins ,Actin remodeling ,Cell Biology ,Actin cytoskeleton ,Actins ,Endocytosis ,Cell biology ,Actin Cytoskeleton ,Cytoskeletal Proteins ,Actin-Related Protein 3 ,Formins ,Actin-Related Protein 2 ,biology.protein ,MDia1 ,Lamellipodium ,Cortactin ,Protein Binding ,Signal Transduction - Abstract
Recently, two new ligands of the Arp2/3 complex have been described that may shed light on the way cells organize complex networks of actin in response to signals. Abp1p, a yeast protein involved in endocytosis, and cortactin, a mammalian src substrate, both enhance the ability of the Arp2/3 complex to assemble branched actin filament networks.
- Published
- 2001