1. Evaluation of Biochemical and Clinical Parameters of Hypertension with Type 2 Diabetes Mellitus
- Author
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Elena Ardeleanu, Daniela Gurgus, Liliana Strat, Mihaela Boanca, Carmen Gadau, Roxana Folescu, Roxana Darabont, Andreea Varga, Alexandra Simona Zamfir, Maria Dorobantu, Ioan Tilea, Teim Baaj, and Patricia Nicola
- Subjects
medicine.medical_specialty ,Process equipment ,business.industry ,Materials Science (miscellaneous) ,Process Chemistry and Technology ,General Engineering ,Type 2 Diabetes Mellitus ,General Chemistry ,General Medicine ,010501 environmental sciences ,01 natural sciences ,General Biochemistry, Genetics and Molecular Biology ,03 medical and health sciences ,0302 clinical medicine ,Petrochemistry ,Materials Chemistry ,medicine ,030212 general & internal medicine ,General Pharmacology, Toxicology and Pharmaceutics ,Intensive care medicine ,business ,0105 earth and related environmental sciences - Abstract
The aim of this study was to assess the basic biochemical and clinical characteristics of patients with hypertension and type 2 diabetes mellitus (T2DM), office blood pressure (BP) and 24-h BP profile, their risk factors and associated comorbidities. Compared with non-diabetics, hypertensive patients with T2DM were older, with a longer duration of hypertension (5.9 vs. 4.7 years), greater office blood pressure and ambulatory BP values, increased incidence of multiple risk factors, target organ damage and cardiovascular disease. Biochemical data in hypertension with T2DM revealed significantly high levels of LDL cholesterol, triglycerides, creatinine, micro- and macro-albuminuria and a reduced estimated glomerular filtration rate. The presence of diabetes was associated with obesity, represented by a BMI ]30 kg/m2 (OR 2.08 [95% CI 1.26-3.45], p = 0.004), abdominal obesity (OR 1.85 [95% CI 1.11-3.04], p = 0.016), high LDL cholesterol (OR 2.02 [95% CI 1.22-3.35], p = 0.006) and high triglycerides (OR 1.86 [95% CI 1.11-3.11], p = 0.017).
- Published
- 2018
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