1. Analysis of the role of Chest X-Ray in a large cohort of 1117 patients with SARS-CoV-2 infection: an Italian multicenter study
- Author
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Alice Scarabelli, Andrea Gori, Sandro Magnani, Sonia Ippolito, Matteo Agostino Orlandi, Chiara Villa, Massimo Galli, Maria Carmela Andrisani, Stefano Fusco, Andrea Antonio Ianiello, Letizia Di Meglio, Andrea Coppola, Guido Giovanni Plensich, Gianpaolo Carrafiello, Alberto Cazzulani, Giuliano Rizzardini, Antonio Pesenti, Valentina Vespro, Genti Xhepa, A. M. Ierardi, Stefano Aliberti, Francesco Blasi, Emanuele Catena, Luigia Scudeller, Barbara Pirrò, Elvira Stellato, Giacomo Grasselli, Mario Petrillo, Guglielmo Damiani, and Giuseppe Cipolla
- Subjects
medicine.medical_specialty ,Multicenter study ,business.industry ,Internal medicine ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,medicine ,business ,Large cohort - Abstract
Objective. To describe the radiographic key patterns on CXR in patients with SARS-CoV-2 infection, assessing the prevalence of radiographic signs of interstitial pneumonia. To evaluate pattern variation between a baseline and a follow-up CXR.Materials and methods. 1117 patients tested positive for SARS-CoV-2 infection were retrospectively enrolled from four centers in Lombardy region. All patients underwent a CXR at presentation. Follow-up CXR was performed when clinically indicated.Two radiologists in each center reviewed CXR images and classified them as suggestive or not for interstitial pneumonia, recording the presence of ground-glass opacity (GGO), reticular pattern or consolidation and their distribution.Pearson’s chi-square test for categorical variables and McNemar test (chi-square for paired data) were performed.Results. Patients mean age 63.3 years, 767 were males (65.5%). The main result is the large proportion of positive CXR in COVID-19 patients.Baseline CXR was positive in 940 patients (80.3%), with significant differences in age and sex distribution between patients with positive and negative CXR. 382 patients underwent a follow-up CXR. The most frequent pattern on baseline CXR was the GGO (66.1%), on follow-up was consolidation (53.4%). The most common distributions were peripheral and middle-lower lung zone.Conclusions. We described key-patterns and their distribution on CXR in a large cohort of COVID-19 patients: GGO was the most frequent finding on baseline CXR, while we found an increase in the proportion of lung consolidation on follow-up CXR. CXR proved to be a reliable tool in our cohort obtaining positive results in 80.3% of the baseline cases.
- Published
- 2020