1. Efficacy of erector spinae plane block versus thoracic paravertebral block for postoperative analgesia in modified radical mastectomy: a randomized controlled trial
- Author
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Domenico Pietro Santonastaso, Annabella Chiara, Roberto Righetti, Diego Marandola, Andrea Sica, Claude T. Bagaphou, Chiara Rosato, Andrea Tognù, Annalisa Curcio, Leonardo Lucchi, Emanuele Russo, and Vanni Agnoletti more...
- Abstract
Background Postoperative analgesia in breast surgery is difficult due to the extensive nature of the surgery and the complex innervation of the breast; general anesthesia can be associated with regional anesthesia techniques to control intra- and post-postoperative pain. This randomized controlled study aimed to compare the efficacy of the erector spinae plane block and the thoracic paravertebral block in radical mastectomy procedures with or without axillary emptying. Methods This prospective, randomized controlled trial included 82 adult females who were randomly divided into two groups using a computer-generated random number. Both groups received general anesthesia, Groups P and E (41 patients each) associated with a single-shot thoracic paravertebral block and a single-shot erector spinae plane block, respectively. Postoperative pain intensity (expressed as Numeric Rating Scale), patients who needed rescue analgesic, intra- and post-operative opioid consumption, post-operative nausea and vomiting, length of stay, adverse events, chronic pain at 6 months, andthe patient’s satisfaction were recorded. Results At 2 h (pConclusions: Both thoracic paravertebral block and erector spinae plane block can be effectively used in controlling post-mastectomy pain and reduce intra- and post-operative opioid consumption. Trial registration The study was prospectively registered on Clinicaltrials.com (trial identifier NCT04457115) (first registration 27/04/2020). more...
- Published
- 2023
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