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Objective: To explore application of thromboelastography(TEG) on clot formation evaluation of patients with Ovarian Hyperstimulation Syndrome(OHSS). Methods: A total of 35 patients with OHSS and 21 patients without OHSS after embryo transfer therapy were received TEG test and conventional coagulation parameters test, including prothrombin time(PT), activated partial thromboplastin time(APTT), fibrinogen(FIB), etc. The change of conventional coagulation parameters and TEG indicators were analyzed between OHSS and control groups, as well as before and after treatment in OHSS group. Results:(1) Comparing with control group, PT time was significantly higher, while FIB levels were significantly lower in OHSS group. However, no significant difference was found on APTT time(P=0.112).(2) TEG showed that the coagulation index(CI) of OHSS group was significantly higher than that of control group(3.6±0.7:0.8±0.5).(3) After treatment, the average CI of OHSS group was 2.8±0.9, which was significantly decreased than admission(P<0.01). Conclusion: TEG test might be used for the coagulation function evaluation in OHSS patients, and provided important evidence for prevention, judgment and treatment of thrombosis. [ABSTRACT FROM AUTHOR]