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Objective: To compare the incidence of postoperative complications and long-term survival outcomes between laparoscopic radical hysterectomy (LRH) and open radical hysterectomy (ORH) in the treatment of early-stage of cervical cancer. Methods: Patients with stage IA2 to IIA cervical cancer who underwent ORH and LRH in Xinjiang Provincial Tumor Hospital from January 2008 to December 2012 were reviewed. Results: The intraoperative blood loss of ORH group was obviously higher than that of the LRH group [(431.15± 126.89)mL vs.(141.83± 53.12)mL, P< 0.001], while the number of cleared lymph, node was obviously lower[ (22.91± 8.38) vs. (26.41± 10.24), P< 0.001], No significant difference was found in the intraoperative and postoperative complication between two groups (P> 0.05). The 1,3, 5-year disease free survival (DFS) rate of ORH and LRH group were 95.08%, 87.23%,72.55% and 98.80%, 89.53%, 77.30% respectively, There was no statistically significant difference between the two groups in the DFS rate(P=0. 056), but the DFS rate of LRH group was higher than that of the ORH group when the tumor size≥ 4 cm (P=0.014 ). Conclusion: LRH was an oncologically safe alternative to ORH and was associated with fewer postoperative complication and earlier recovery, LRH might contribute to higher DFS rate of early-stage of cervical cancer patients whose of early-stage of cervical cancer. [ABSTRACT FROM AUTHOR]