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Objective:To investigate the clinical characteristics and risk factors between different age patients with coronary artery disease (CAD).Methoda:Using retrospective study,480 CAD patients underwent coronary angiogram and interventional therapy in our hospital from 2010 to 2014 were selected,including 320 cases of elder patients(A group) and 160 cases of young and middle age patients (B group).Clinical data,stenosis of coronary artery,disease types and incidence rate of adverse events were analyzed in two groups,compared the laboratory indexes in two groups,and then multiple linear regression analysis was conducted on factors with statistical significance in single factor analysis to explore the risk factors of CAD.Results:(1)The sex ratio and hypertension between the A group and B group showed statistically significance difference (P＜0.05).(2)The incidence of single and triple vessel disease in the A group was significantly higher than that of B group (P＜0.05).The adverse events in the A group were more than those in the B group,including bleeding,arrhythmia and cardiogenic shock(all P＜0.05).(3)The creatinine (Cr),plasma prothrombin time (PT),fibrinogen (FIB) in the A group were significantly higher than B group,but gamma-glutamyltransferase (GGT),tdacylglycerol (TG),homocysteine (Hcy) and platelet count (PLT) were significantly lower than the B group (P＜0.05).(4)Multiple factor regression analysis showed that Hcy and FIB were risk factors of CAD (P＜0.05).Conclusion:There were significant difference between different age patients with CAD in the clinical characteristics,besides the Hey and FIB were the risk factors of CAD.It suggests that the treatment should be different for CAD between the elderly and the young,middle-aged patients with CAD. [ABSTRACT FROM AUTHOR]

Objective: To investigate the relationship between serum parathyroid hormone(PTH) level and nutritional status in patients with chronic renal failure(CTo explore the influencing factors on prognosis of patients with cardiopulmonary resuscitation return of spontaneous circulation(ROSC), and to provide reference for clinical disease guidance. Methods: Collected the medical records of 148 patients with sudden cardiac arrest who were underwent cardiopulmonary resuscitation and ROSC in our hospital from January 2012 to January 2015, analyzed the prognosis of patients, and used logistic regression equation to analyze its influencing factors. Results: There were 48 cases(32.43%) of patients with good prognosis,and 100 cases(67.57%) of patients with poor prognosis.Time from sudden cardiac arrest to resuscitation start, time from resuscitation start to ROSC, 72 h body temperature after resuscitation, myoclonus or smoke after resuscitation, D-dimer(D-D) levels after resuscitation, blood p H value after resuscitation, acute physiology and chronic health evaluation(APACHEII) score 3d after resuscitation were risk factors for the prognosis of patients with cardiopulmonary resuscitation and ROSC(P<0.05). Conclusion: There are many factors that affect the prognosis of patients with cardiopulmonary resuscitation and ROSC, when rescuing patients with sudden cardiac arrest, cardiopulmonary resuscitation should be shortened as far as possible,and follow the principle of rescue in 10 min, it may help improving prognosis. [ABSTRACT FROM AUTHOR]