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required a small increase in core temperature to 33.6*0.15”C. Meperidine and buspirone did not cause respiratory depression or other complications. Patients with shivering were younger (54 * 10 years vs. 59 * 12 years. p=O.O4), and received a higher total bolus dose of meperidine than those without shivering (156 f 66mg vs. 120 f 66mg, p=O.Ol). Mean patient weight and body surface area were similar in bath groups and no other demographic, clinical or hemodynamlc predictors of shivering were identified. Conclusion: Our results indicate that combination treatment with surface warming, buspirone and meperidine is safe and effective in patients with AMI, and provides a novel method for counteracting thermoregulatory defenses to systemic hypothermia during endovascular cooling. SES to control bare stents (CS), 462 pts (44%) had single vessel LAD treatment. In this cohort, reference vessel size was 2.74mm and lesion length was 14.0 mm. Results: Clinical (@ 9 months) and angiographic (@ 8 months) outcomes were compared in the SES and CS LAD subgroups (see table). Conclusions: The SIRIUS LAD substudy indicates striking improvement after SES in all clinical and angiographic efficacy parameters compared with CS. These SES results are equivalent to those reported after LIMA surgery, and thus, SES should be considered the new standard of care for stngle vessel LAD therapy.