1. Outcomes in Critically Ill Patients with Cancer-Related Complications
- Author
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Fernando A. Bozza, Eliezer Silva, Ederlon Rezende, Viviane B. L. Torres, André Peretti Torelly, José Mario Meira Teles, Marcio Soares, Nelson Spector, Juliana Vassalo, Luciano Cesar Pontes Azevedo, Ulysses V. A. Silva, Jorge I. F. Salluh, M Knibel, José J. Netto, Pedro Caruso, and Claudio Piras
- Subjects
Male ,Pediatrics ,Pulmonology ,Gastrointestinal Diseases ,medicine.medical_treatment ,Cancer Treatment ,lcsh:Medicine ,Hematologic Cancers and Related Disorders ,0302 clinical medicine ,Neoplasms ,Odds Ratio ,Medicine and Health Sciences ,Medicine ,Hospital Mortality ,Prospective Studies ,Prospective cohort study ,lcsh:Science ,Multidisciplinary ,Mortality rate ,Venous Thromboembolism ,Hematology ,Middle Aged ,Prognosis ,Hospitals ,Intensive Care Units ,Oncology ,030220 oncology & carcinogenesis ,Female ,Respiratory Insufficiency ,Research Article ,Clinical Oncology ,medicine.medical_specialty ,Death Rates ,Critical Illness ,Radiation Therapy ,Antineoplastic Agents ,03 medical and health sciences ,Population Metrics ,Respiratory Failure ,Renal Dialysis ,Intensive care ,Internal medicine ,Humans ,Dialysis ,Aged ,Neoplasm Staging ,Demography ,Performance status ,Population Biology ,business.industry ,lcsh:R ,Biology and Life Sciences ,Cancers and Neoplasms ,030208 emergency & critical care medicine ,Odds ratio ,Hematologic Diseases ,Respiration, Artificial ,Health Care ,Logistic Models ,Respiratory failure ,Health Care Facilities ,People and Places ,lcsh:Q ,Clinical Medicine ,business ,Complication - Abstract
Introduction Cancer patients are at risk for severe complications related to the underlying malignancy or its treatment and, therefore, usually require admission to intensive care units (ICU). Here, we evaluated the clinical characteristics and outcomes in this subgroup of patients. Materials and Methods Secondary analysis of two prospective cohorts of cancer patients admitted to ICUs. We used multivariable logistic regression to identify variables associated with hospital mortality. Results Out of 2,028 patients, 456 (23%) had cancer-related complications. Compared to those without cancer-related complications, they more frequently had worse performance status (PS) (57% vs 36% with PS≥2), active malignancy (95% vs 58%), need for vasopressors (45% vs 34%), mechanical ventilation (70% vs 51%) and dialysis (12% vs 8%) (P
- Published
- 2016