Search

Your search keyword '"Ming-Chia Lin"' showing total 4 results
Start Over Author "Ming-Chia Lin" Publisher public library of science (plos)
4 results on '"Ming-Chia Lin"'

1. Risk of Nephrotic Syndrome following Enteroviral Infection in Children: A Nationwide Retrospective Cohort Study.

Author

Jiun-Nong Lin, Cheng-Li Lin, Chi-Hui Yang, Ming-Chia Lin, Chung-Hsu Lai, Hsi-Hsun Lin, and Chia-Hung Kao

Subjects
Medicine, Science
Abstract

Nephrotic syndrome is a common chronic illness encountered during childhood. Infections have been identified as a cause of nephrotic syndrome. The aim of this study was to evaluate the association between enteroviral infection and nephrotic syndrome.A nationwide retrospective cohort study was conducted by analyzing data from the National Health Insurance Research Database in Taiwan. Children aged

Published
2016
Full Text
View/download PDF

2. A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study.

Author

Wen-Yuan Lee, Li-Min Sun, Ming-Chia Lin, Ji-An Liang, Shih-Ni Chang, Fung-Chang Sung, Chih-Hsin Muo, and Chia-Hung Kao

Subjects
Medicine, Science
Abstract

BACKGROUND: Controversy still exists regarding whether alendronate (ALN) use increases the risk of esophageal cancer or breast cancer. METHODS: This paper explores the possible association between the use of oral ALN in osteoporosis patients and subsequent cancer risk using the National Health Insurance (NHI) system database of Taiwan with a Cox proportional-hazard regression analysis. The exposure cohort contained 5,624 osteoporosis patients used ALN and randomly frequency-matched by age and gender of 3 osteoporosis patients without any kind of anti-osteoporosis drugs in the same period. RESULTS: For a dose ≥ 1.0 g/year, the risk of developing overall cancer was significantly higher (hazard ratio: 1.69, 95% confidence ratio: 1.39-2.04) than in osteoporosis patients without any anti-osteoporosis drugs. The risks for developing liver, lung, and prostate cancers and lymphoma were also significantly higher than in the control group. CONCLUSIONS: This population-based retrospective cohort study did not find a relationship between ALN use and either esophageal or breast cancer, but unexpectedly discovered that use of ALN with dose ≥ 1.0 g/year significantly increased risks of overall cancer incidence, as well as liver, lung, and prostate cancers and lymphoma. Further large population-based unbiased studies to enforce our findings are required before any confirmatory conclusion can be made.

Published
2012
Full Text
View/download PDF

3. Risk of Nephrotic Syndrome following Enteroviral Infection in Children: A Nationwide Retrospective Cohort Study

Author

Chi-Hui Yang, Chia-Hung Kao, Cheng-Li Lin, Chung-Hsu Lai, Ming-Chia Lin, Hsi-Hsun Lin, and Jiun-Nong Lin

Subjects
0301 basic medicine, Male, RNA viruses, Pediatrics, Viral Diseases, Nephrotic Syndrome, Pulmonology, Prevalence, Eczema, lcsh:Medicine, Atopic Dermatitis, Comorbidity, Kaplan-Meier Estimate, Pathology and Laboratory Medicine, Enteroviruses, Cohort Studies, Families, 0302 clinical medicine, Allergies, Medicine and Health Sciences, 030212 general & internal medicine, Child, lcsh:Science, Children, Rhinitis, Multidisciplinary, Allergic Diseases, Incidence (epidemiology), virus diseases, Atopic dermatitis, Coxsackieviruses, Infectious Diseases, Medical Microbiology, Child, Preschool, Viral Pathogens, Viruses, Female, Pathogens, Pediatric Infections, Cohort study, Research Article, Allergic Rhinitis, medicine.medical_specialty, Immunology, Taiwan, Dermatology, Rhinovirus Infection, Microbiology, 03 medical and health sciences, medicine, Enterovirus Infections, Humans, Intensive care medicine, Microbial Pathogens, Proportional Hazards Models, Retrospective Studies, Biology and life sciences, business.industry, Proportional hazards model, lcsh:R, Organisms, Infant, Retrospective cohort study, Rhinology, medicine.disease, 030104 developmental biology, Enterovirus Infection, Socioeconomic Factors, Otorhinolaryngology, Age Groups, People and Places, Respiratory Infections, Nasal Diseases, Population Groupings, Clinical Immunology, lcsh:Q, Clinical Medicine, business, Nephrotic syndrome
Abstract

Purpose Nephrotic syndrome is a common chronic illness encountered during childhood. Infections have been identified as a cause of nephrotic syndrome. The aim of this study was to evaluate the association between enteroviral infection and nephrotic syndrome. Methods A nationwide retrospective cohort study was conducted by analyzing data from the National Health Insurance Research Database in Taiwan. Children aged

Published
2016

4. A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study

Author

Chia-Hung Kao, Shih Ni Chang, Chih Hsin Muo, Wen-Yuan Lee, Fung-Chang Sung, Li-Min Sun, Ming Chia Lin, and Ji An Liang

Subjects
Male, Oncology, Databases, Factual, Esophageal Neoplasms, Epidemiology, Osteopenia and Osteoporosis, lcsh:Medicine, Cohort Studies, Prostate cancer, Neoplasms, Breast Tumors, lcsh:Science, Aged, 80 and over, education.field_of_study, Multidisciplinary, Alendronate, Bone Density Conservation Agents, Incidence, Hazard ratio, Obstetrics and Gynecology, Middle Aged, Cohort, Medicine, Female, Research Article, Cohort study, Adult, Risk, Drugs and Devices, medicine.medical_specialty, Esophageal Cancer, Clinical Research Design, Population, Taiwan, Breast Neoplasms, Breast cancer, Internal medicine, Breast Cancer, Gastrointestinal Tumors, medicine, Humans, education, Biology, Aged, Retrospective Studies, Gynecology, Population Biology, business.industry, Pharmacoepidemiology, lcsh:R, Cancers and Neoplasms, Cancer, Retrospective cohort study, medicine.disease, Women's Health, Osteoporosis, lcsh:Q, business
Abstract

Background Controversy still exists regarding whether alendronate (ALN) use increases the risk of esophageal cancer or breast cancer. Methods This paper explores the possible association between the use of oral ALN in osteoporosis patients and subsequent cancer risk using the National Health Insurance (NHI) system database of Taiwan with a Cox proportional-hazard regression analysis. The exposure cohort contained 5,624 osteoporosis patients used ALN and randomly frequency-matched by age and gender of 3 osteoporosis patients without any kind of anti-osteoporosis drugs in the same period. Results For a dose ≥1.0 g/year, the risk of developing overall cancer was significantly higher (hazard ratio: 1.69, 95% confidence ratio: 1.39–2.04) than in osteoporosis patients without any anti-osteoporosis drugs. The risks for developing liver, lung, and prostate cancers and lymphoma were also significantly higher than in the control group. Conclusions This population-based retrospective cohort study did not find a relationship between ALN use and either esophageal or breast cancer, but unexpectedly discovered that use of ALN with dose ≥1.0 g/year significantly increased risks of overall cancer incidence, as well as liver, lung, and prostate cancers and lymphoma. Further large population-based unbiased studies to enforce our findings are required before any confirmatory conclusion can be made.

Published
2012

Catalog

Books, media, physical & digital resources
See catalog results