1. Association among presence of cancer pain, inadequate pain control, and psychotropic drug use
- Author
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María Paz-Zulueta, Ana Rosa Alconero-Camarero, Miguel Santibáñez, María Cristina Alonso-Blanco, Paloma Salvadores-Fuentes, Paula Parás-Bravo, and Universidad de Cantabria
- Subjects
Male ,Cross-sectional study ,Cancer Treatment ,lcsh:Medicine ,Hypnotic ,0302 clinical medicine ,Medicine and Health Sciences ,Odds Ratio ,Hypnotics and Sedatives ,Medicine ,030212 general & internal medicine ,lcsh:Science ,Analgesics ,Multidisciplinary ,Pharmaceutics ,Medical record ,Hormonal Therapy ,Drugs ,Antidepressants ,Cancer Pain ,Middle Aged ,Antidepressive Agents ,Psychotropic drug ,Oncology ,030220 oncology & carcinogenesis ,Anesthesia ,Antidepressant ,Female ,Research Article ,Antipsychotic Agents ,medicine.medical_specialty ,medicine.drug_class ,03 medical and health sciences ,Drug Therapy ,Adverse Reactions ,Internal medicine ,Pain Management ,Humans ,Aged ,Pharmacology ,Psychotropic Drugs ,business.industry ,lcsh:R ,Odds ratio ,Confidence interval ,Cross-Sectional Studies ,Logistic Models ,Anti-Anxiety Agents ,lcsh:Q ,business ,Cancer pain ,Anxiolytics - Abstract
Introduction Pain is a common symptom in cancer patients, and its control and management are complex. Despite the high concomitant use of psychotropic drugs among such patients, the association among pain, inadequate pain control, and psychotropic drug use has not been fully determined. This study examined the prevalence of cancer pain and inadequate pain control and the association with psychotropic drug use. Materials and methods In this cross-sectional study, we investigated 402 medical records obtained by simple random sampling of oncology patients at a hospital in northern Spain from July 2012 to July 2014. Adjusted odds ratios (ORs) were estimated together with their 95% confidence intervals (95% CIs) by unconditional logistic regression for each type of psychotropic drug (anxiolytics, hypnotics, and antidepressants). Results The mean patient age was 61.17 (standard deviation ± 13.14) years; 57.5% were women, 42.5% men. Pain was present in 18.4% of patients and inadequate pain control in 54.2%. We found a statistically significant association between the presence of cancer pain and anxiolytic use (adjusted OR, 3.15; 95% CI, 1.49–6.68) and hypnotic use (adjusted OR, 5.19; 95% CI, 1.77–15.25). Inadequate pain control was associated to a greater extent with the use of those drugs: adjusted OR for anxiolytic use, 4.74 (95% CI, 1.91–11.80); adjusted OR for hypnotic use, 6.09 (95% CI, 1.74–21.32). By contrast, no association was found between pain and antidepressant use (adjusted OR, 0.99). Conclusion The presence of pain and (to a greater extent) poor pain control were associated with increased use of certain psychotropic drugs, such as anxiolytics and hypnotics. There appeared to be no association between pain and antidepressant use.
- Published
- 2017