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The relationship between objectively measured physical activity and blood metal concentrations in patients with MoM hip replacements was investigated in two different cohort studies. The average number of steps per day of the patients in these studies was comparable to healthy subjects of the same age. This indicates a normal activity level of the patient population in this study. There was a wide variation in the cobalt concentrations of the patients. A significant correlation was found between cobalt concentrations and various parameters of daily physical activity (number of sit-to-stand transfers and high-intensity peaks). No statistically significant relationships were found between cobalt concentrations and daily time spent walking, total number of steps and total percentage of time physically active. It seems that quantitative general daily activities, such as normal walking, do not influence cobalt concentrations, or do so only slightly. Especially qualitative aspects of the activities (high intensity, fast walking, many sit-to-stand transfers) seem to influence cobalt concentrations. It also compared the activity found in patients with MoM prostheses with patients with conventional prostheses. The groups were similar in terms of gender, age at surgery, follow-up since surgery and BMI. Contrary to expectations, patients with an HRA were not found to be more physically active. Patients show similar physical activities independent of the type of implant. These patients were also asked to complete questionnaires (PROMs), asking about their physical activity. It turned out that these questionnaires hardly correspond to the objectively measured physical activity. Using the Dutch National Register of Orthopaedic Implants (LROI), there was an investigation as to whether the replacement (revision) of a MoM prosthesis was comparable to the revision of a non-MoM prosthesis in terms of outcomes. Revision surgery for failed MoM hip replacements has a high risk of rev

The relationship between objectively measured physical activity and blood metal concentrations in patients with MoM hip replacements was investigated in two different cohort studies. The average number of steps per day of the patients in these studies was comparable to healthy subjects of the same age. This indicates a normal activity level of the patient population in this study. There was a wide variation in the cobalt concentrations of the patients. A significant correlation was found between cobalt concentrations and various parameters of daily physical activity (number of sit-to-stand transfers and high-intensity peaks). No statistically significant relationships were found between cobalt concentrations and daily time spent walking, total number of steps and total percentage of time physically active. It seems that quantitative general daily activities, such as normal walking, do not influence cobalt concentrations, or do so only slightly. Especially qualitative aspects of the activities (high intensity, fast walking, many sit-to-stand transfers) seem to influence cobalt concentrations. It also compared the activity found in patients with MoM prostheses with patients with conventional prostheses. The groups were similar in terms of gender, age at surgery, follow-up since surgery and BMI. Contrary to expectations, patients with an HRA were not found to be more physically active. Patients show similar physical activities independent of the type of implant. These patients were also asked to complete questionnaires (PROMs), asking about their physical activity. It turned out that these questionnaires hardly correspond to the objectively measured physical activity. Using the Dutch National Register of Orthopaedic Implants (LROI), there was an investigation as to whether the replacement (revision) of a MoM prosthesis was comparable to the revision of a non-MoM prosthesis in terms of outcomes. Revision surgery for failed MoM hip replacements has a high risk of rev