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The Middle East (ME) spans the transition between a temperate Mediterranean climate in the Levant to hyper-arid sub-tropical deserts in the southern part of the Arabian Peninsula (AP), with the complex alpine topography in the northeast feeding the Euphrates and Tigris rivers which support life in the Southeastern Fertile Crescent (FC). Climate projections predict severe drying in several parts of the ME in response to global warming, making it important to understand the controls of hydro-climate perturbations in the region. Here we discuss 23 ME speleothem stable oxygen isotope (δ18Occ) records from 16 sites from the SISAL_v1 database (Speleothem Isotope Synthesis and Analysis database), which provide a record of past hydro-climatic variability. Sub-millennial changes in ME δ18Occ values primarily indicate changes in past precipitation amounts the result of the main synoptic pattern in the region, specifically Mediterranean cyclones. This pattern is superimposed on change in vapor source δ18O composition. The coherency (or lack thereof) between regional records is reviewed from Pleistocene to present, covering the Last Glacial Maximum (~22 ka), prominent events during deglaciation, and the transition into the Holocene. The available δ18Occ time-series are investigated by binning and normalizing at 25-year and 200-year time windows over the Holocene. Important climatic oscillations in the Holocene are discussed, such as the 8.2 ka, 4.2 ka and 0.7 ka (the Little Ice Age) Before Present events. Common trends in the normalized anomalies are tested against different climate archives. Finally, recommendations for future speleothem-based research in the region are given along with comments on the utility and completeness of the SISAL database., Y.B. acknowledges support of FFB grant #3-323/4532211. B.M. acknowledges support from the CSIC Ramón y Cajal postdoctoral programme RYC-2013-14073. M.A.L. acknowledges support from the Ministry of Science and Technology (MOST), Taiwan (107-2119-M-002-051). M.D. acknowledges funding by the German Research Foundation (DFG) grant DE 2398/3-1.

Speleothem oxygen isotope records from the Caribbean, Central, and North America reveal climatic controls that include orbital variation, deglacial forcing related to ocean circulation and ice sheet retreat, and the influence of local and remote sea surface temperature variations. Here, we review these records and the global climate teleconnections they suggest following the recent publication of the Speleothem Isotopes Synthesis and Analysis (SISAL) database. We find that low-latitude records generally reflect changes in precipitation, whereas higher latitude records are sensitive to temperature and moisture source variability. Tropical records suggest precipitation variability is forced by orbital precession and North Atlantic Ocean circulation driven changes in atmospheric convection on long timescales, and tropical sea surface temperature variations on short timescales. On millennial timescales, precipitation seasonality in southwestern North America is related to North Atlantic climate variability. Great Basin speleothem records are closely linked with changes in Northern Hemisphere summer insolation. Although speleothems have revealed these critical global climate teleconnections, the paucity of continuous records precludes our ability to investigate climate drivers from the whole of Central and North America for the Pleistocene through modern. This underscores the need to improve spatial and temporal coverage of speleothem records across this climatically variable region.