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16 results on '"K. D. Buchanan"'

4. Non-Invasive Investigation of Diabetic Cardiomyopathy

Author

K. D. Buchanan, Patrick M. Bell, S. Vallely, I. C. Steele, D. P. Nicholls, A.-M. Nugent, A. Moore, N. P. S. Campbell, and Elisabeth R. Trimble

Subjects
medicine.medical_specialty, business.industry, Internal medicine, Diabetic cardiomyopathy, Non invasive, medicine, Cardiology, General Medicine, medicine.disease, business
Published
1994
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5. Effect of guar on second-meal glucose tolerance in normal man

Author

K. G. M. M. Alberti, M. F. Laker, T. R. Trinick, Desmond G. Johnston, K. D. Buchanan, and M.J. Keir

Subjects
Adult, Blood Glucose, Male, medicine.medical_specialty, Metabolic Clearance Rate, Diet therapy, Guar, Galactans, Glucagon, Mannans, Gastric inhibitory polypeptide, Internal medicine, Plant Gums, Humans, Insulin, Medicine, Pancreatic polypeptide, Meal, Glucose tolerance test, Guar gum, medicine.diagnostic_test, business.industry, General Medicine, Glucose Tolerance Test, Endocrinology, Lactates, business
Abstract

1. Whole body glucose turnover and absorption of a 50 g glucose drink was studied in six healthy volunteers on two occasions, 4 h after a ‘breakfast’ of 50 g of glucose, mixed on one occasion with 20 g of guar gum. 2. Plasma glucose concentrations were significantly reduced with guar gum compared with those obtained without guar gum (P < 0.0001). 3. Whole body glucose turnover studied by an intravenous primed dose constant infusion technique using d-[3-3H]glucose showed no significant difference between the two groups: 353 ± 15 mmol with guar and 350 ± 9 mmol without guar. 4. Total oral glucose absorption, followed with a D-[1-14C]glucose tracer, was significantly decreased by guar treatment, being 219 ± 3 mmol with guar and 239 ± 5 mmol without guar (P < 0.05). 5. Serum insulin levels were lowered by guar treatment (P 6. Blood lactate concentrations were raised in the guar treated group (P < 0.05) whereas pyruvate, alanine, glycerol and 3-hydroxybutyrate concentrations did not differ significantly. 7. These results support the suggestion that guar improves second-meal tolerance to glucose by decreasing absorption.

Published
1986
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13. Eating, Exercise and Pancreatic Poly Peptide in Obesity

Author

A. M. Cornell, M. M. T. O'Hare, W. J. Andrews, and K. D. Buchanan

Subjects
chemistry.chemical_classification, medicine.medical_specialty, Endocrinology, chemistry, business.industry, Internal medicine, medicine, Peptide, General Medicine, business, medicine.disease, Obesity
Published
1979
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15. Impaired Secretin Release in Coeliac Disease

Author

K. D. Buchanan, J. C. McLoughlin, and F. A. O'Connor

Subjects
medicine.medical_specialty, business.industry, Internal medicine, Medicine, General Medicine, business, medicine.disease, Gastroenterology, Coeliac disease, Secretin
Published
1977
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16. Gastrin and Duodenal Ulceration

Author

Joy Ardill, K. D. Buchanan, T.L. Kennedy, and J. R. Hayes

Subjects
Eating, medicine.medical_specialty, Duodenal ulceration, business.industry, Duodenal Ulcer, Internal medicine, Gastrins, medicine, Humans, General Medicine, business, Gastroenterology, Gastrin
Published
1973
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