Search

Your search keyword '"Glinka R"' showing total 15 results
Start Over Author "Glinka R" Publisher polski towarzystwo farmaceutyczne
15 results on '"Glinka R"'

1. Search for new non-nucleoside inhibitors of HIV-1 reverse transcriptase (HIV-1 RT).

Author

Brzezińska E and Glinka R

Subjects
HIV Reverse Transcriptase metabolism, Reverse Transcriptase Inhibitors chemistry, Reverse Transcriptase Inhibitors pharmacology, HIV Reverse Transcriptase antagonists & inhibitors, Reverse Transcriptase Inhibitors chemical synthesis
Abstract

The derivatives of dibenzoxazocinone, dibenzoxadiazocine, dibenzoxadiazonine, and benzodiazepine systems were synthesized as potential lead compounds for inhibitors of HIV-1 reverse transcriptase. The suggested structures were derived from analysis of the described spatial and physicochemical requirements for HIV-1 RT inhibitors. All of the evaluated compounds (apart from the oxadiazocine derivatives) showed a week inhibitory activity on recombinant HIV-1 RT from Escherichia coli.

Published
2002

3. [Synthesis and pharmacological properties of new 4-chlorophenoxyacetic acid derivatives].

Author

Szadowska A, Mazur M, Graczyk J, Kiełek MB, Guryn R, Mikołajewska H, Glinka R, and Kotełko B

Subjects
2,4-Dichlorophenoxyacetic Acid chemical synthesis, 2,4-Dichlorophenoxyacetic Acid pharmacology, Animals, Antihypertensive Agents, Blood Pressure drug effects, Body Temperature drug effects, Chemical Phenomena, Chemistry, Depression, Chemical, Guinea Pigs, Humans, Ileum drug effects, Mice, Mice, Inbred BALB C, Motor Activity drug effects, Muscle, Smooth drug effects, Rabbits, Rats, Rats, Inbred Strains, Sleep drug effects, Stereotyped Behavior drug effects, Tranquilizing Agents, 2,4-Dichlorophenoxyacetic Acid analogs & derivatives
Published
1982

6. [Synthesis and pharmacological studies of new 1,4,7-oxadiazonine and 1,5,6-oxadiazonine derivatives].

Author

Mikiciuk-Olasik E, Glinka R, Kotełko B, Szadowska A, and Kiełek MB

Subjects
Animals, Chemical Phenomena, Chemistry, Drug Evaluation, Preclinical, Female, Male, Mice, Mice, Inbred BALB C, Oxazines pharmacology, Rabbits, Rats, Rats, Inbred Strains, Tranquilizing Agents, Vasodilator Agents, Blood Pressure drug effects, Motor Activity drug effects, Oxadiazoles chemical synthesis, Oxazines chemical synthesis
Published
1984

8. [Synthesis of derivatives of perhydroazepine, perhydro-1,5-oxazocine, morpholine and piperazine containing 3-(isopropylamino)-propan-2-ol group--compounds with potential effect on the circulatory system and central nervous system].

Author

Kotełko B, Mikołajewska H, Glinka R, and Guryn R

Subjects
Azepines chemical synthesis, Humans, Morpholines chemical synthesis, Oxazocines chemical synthesis, Piperazine, Piperazines chemical synthesis, Azepines pharmacology, Blood Circulation drug effects, Central Nervous System drug effects, Morpholines pharmacology, Oxazocines pharmacology, Piperazines pharmacology
Published
1985

9. [Synthesis and the effect of new derivatives of perhydro-1,4,6-oxadiazocine on the central nervous system].

Author

Brzezińska E, Glinka R, Szadowska A, and Kiełek MB

Subjects
Animals, Antipsychotic Agents chemical synthesis, Chemical Phenomena, Chemistry, Female, Male, Mice, Motor Activity physiology, Oxazocines chemical synthesis, Rats, Stereotyped Behavior physiology, Antipsychotic Agents pharmacology, Motor Activity drug effects, Oxazocines pharmacology, Stereotyped Behavior drug effects
Published
1988

Catalog

Books, media, physical & digital resources
See catalog results