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Your search keyword '"Mirzoev T"' showing total 14 results
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14 results on '"Mirzoev T"'

12. Early Deсline in Rat Soleus Passive Tension with Hindlimb Unloading: Inactivation of Cross-bridges or Activation of Calpains?

Author

Petrova IO, Tyganov SA, Mirzoev TM, Tsaturyan AK, Kozlovskaya IB, and Shenkman BS

Subjects
Animals, Enzyme Activation, Male, Rats, Rats, Wistar, Time Factors, Calpain chemistry, Calpain metabolism, Hindlimb Suspension, Muscle, Skeletal physiology, Stress, Mechanical
Abstract

The study was aimed at testing the hypotheses about the role of cross-bridges and calpains in reduction of rat soleus passive tension under conditions of hindlimb unloading. For this purpose, we used an inhibitor of μ-calpain PD 150606 as well as a blocker of actomyosin interaction (blebbistatin). It was found for the first time that a decrease in passive tension of rat soleus after 3-day hindlimb unloading is associated with the activity of μ-calpain and does not depend on the processes of cross-bridges formation.

Published
2018
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13. Effect of MGF E-peptide on anabolic and proteolytic signaling pathways in rat m. gastrocnemius medialis.

Author

Mirzoev TM, Turtikova OV, Lomonosova YN, Nemirovskaya TL, Alekseev SM, Kovtun AL, Ushakov IB, and Shenkman BS

Subjects
Animals, Gene Expression Regulation drug effects, Male, Muscle Proteins metabolism, Muscle, Skeletal drug effects, Muscle, Skeletal physiology, Phosphorylation drug effects, Physical Conditioning, Animal, Protein Serine-Threonine Kinases metabolism, Rats, Rats, Wistar, SKP Cullin F-Box Protein Ligases metabolism, Ubiquitin-Protein Ligases metabolism, Insulin-Like Growth Factor I chemistry, Muscle, Skeletal cytology, Muscle, Skeletal metabolism, Peptide Fragments pharmacology, Proteolysis drug effects, Signal Transduction drug effects
Published
2014
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