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13 results on '"Cerbo R"'

2. [Effect of phosphodiesterase inhibitors on neuroleptic-induced catalepsy and apomorphine-induced stereotypic movements in rats].

Author

Cerbo R, Carchedi F, Casacchia M, and Meco G

Subjects
Animals, Atropine pharmacology, Catalepsy drug therapy, Humans, Movement Disorders drug therapy, Papaverine administration & dosage, Phosphodiesterase Inhibitors administration & dosage, Rats, Apomorphine, Catalepsy chemically induced, Haloperidol, Movement Disorders chemically induced, Papaverine therapeutic use, Phosphodiesterase Inhibitors therapeutic use
Published
1978

5. [Animal stereotypy and transmethylation of cerebral amines].

Author

Meco G, Ruggieri S, Carolei A, Cerbo R, Zamponi A, and Agnoli A

Subjects
Amphetamine pharmacology, Animals, Apomorphine pharmacology, Levodopa pharmacology, Movement Disorders drug therapy, Piribedil pharmacology, Rats, Amines metabolism, Brain metabolism, Movement Disorders chemically induced, S-Adenosylmethionine therapeutic use
Published
1975

7. Naloxone-induced jumping activity in morphine-dependent mice: a pharmacological study on the role of DA2 receptors.

Author

Cerbo R, Boni B, De Lena C, Cesarino F, Meco G, Feliciani M, Formisano R, and Casacchia M

Subjects
Animals, Drug Tolerance, Haloperidol pharmacology, Lisuride pharmacology, Male, Mice, Tiapamil Hydrochloride pharmacology, Morphine pharmacology, Motor Activity drug effects, Naloxone pharmacology, Receptors, Dopamine metabolism
Abstract

The morphine withdrawal syndrome is strictly related to modifications on neurotransmittorial systems at central and peripheral levels. Dopamine seems to play an important role. Particularly in the experimental withdrawal syndrome the jumping activity seems to be related to a hypersensitivity of DA receptors. While the role of DA1 receptors has been extensively studied, using agonist and antagonist drugs, the role of DA2 receptors is still little known. In our study we evaluated the changes of the jumping response that was induced by substances active on DA2 receptors (lisuride, tiapride) in mice made acutely dependent on morphine, in which we induced a withdrawal syndrome with naloxone. Haloperidol (DA1-DA2 blocker) did not provoke significant changes. Either tiapride or lisuride determined a sharp increase of jumping.

Published
1984

8. [Usefulness of gamma-glutamyltransferase in alcoholic hepatotoxicity].

Author

Casacchia M, Meco G, Carchedi F, Paris L, Avoli M, and Cerbo R

Subjects
Adult, Alanine Transaminase metabolism, Alkaline Phosphatase metabolism, Aspartate Aminotransferases metabolism, Humans, Middle Aged, Liver Cirrhosis, Alcoholic enzymology, gamma-Glutamyltransferase metabolism
Published
1978

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