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Your search keyword '"Lee, Todd C"' showing total 1 results
Start Over Author "Lee, Todd C" Topic mortality Topic randomized controlled trials Publisher oxford university press / usa
1 results on '"Lee, Todd C"'

1. How Generalizable Are Randomized Controlled Trials (RCTs) in Staphylococcus aureus Bacteremia? A Description of the Mortality Gap Between RCTs and Observational Studies.

Author

Bai, Anthony D, Lo, Carson K L, Komorowski, Adam S, Suresh, Mallika, Guo, Kevin, Garg, Akhil, Tandon, Pranav, Senecal, Julien, Corpo, Olivier Del, Stefanova, Isabella, Fogarty, Clare, Butler-Laporte, Guillaume, McDonald, Emily G, Cheng, Matthew P, Morris, Andrew M, Loeb, Mark, and Lee, Todd C

Subjects
BACTEREMIA, MEDICAL databases, SCIENTIFIC observation, MEDICAL information storage & retrieval systems, SYSTEMATIC reviews, STAPHYLOCOCCAL diseases, RANDOMIZED controlled trials, STAPHYLOCOCCUS aureus, ELIGIBILITY (Social aspects), DEATH, MEDLINE
Abstract

In Staphylococcus aureus bacteremia, mortality rates in randomized controlled trials (RCTs) are consistently lower than observational studies. Stringent eligibility criteria and omission of early deaths in RCTs contribute to this mortality gap. Clinicians should acknowledge the possibility of a lower treatment effect when applying RCT results to bedside care. [ABSTRACT FROM AUTHOR]

Published
2022
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