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10 results on '"Takefumi Mori"'

1. Association Between Ambulatory Blood Pressure and Risk of Home Hypertension in a Normotensive Population: The Ohasama Study

Author

Shingo Nakayama, Michihiro Satoh, Hirohito Metoki, Takahisa Murakami, Yukako Tatsumi, Kei Asayama, Azusa Hara, Takuo Hirose, Megumi Tsubota-Utsugi, Masahiro Kikuya, Takefumi Mori, Atsushi Hozawa, Yutaka Imai, and Takayoshi Ohkubo

Subjects
Internal Medicine
Abstract

BackgroundWe investigated the association between ambulatory blood pressure (BP) and the risk of home hypertension in a normotensive population and whether considering ambulatory BP improves the 10-year prediction model for home hypertension risk, which was developed in the previous Ohasama Study.MethodsIn this prospective study, we followed up with 410 participants (83.2% women; age, 53.6 years) without a home and ambulatory hypertension in the general population of Ohasama, Japan. The Cox model was used to assess the hazard ratios (HRs) for home hypertension (home BP ≥ 135/≥85 mmHg or the initiation of antihypertensive treatment) and model improvement.ResultsDuring a mean 14.2-year follow-up, 225 home hypertension incidences occurred. The HR (95% confidence interval) for home hypertension incidence per 1-SD higher (=6.76 mmHg) 24-hour systolic BP (SBP) was 1.59 (1.33 to 1.90), after adjustments for possible confounding factors, including baseline home SBP. Harrell’s C-statistics increased from 0.72 to 0.73 (P = 0.11) when 24-hour SBP was added to the basic 10-year home hypertension prediction model, which includes sex, age, body mass index, smoking status, office SBP, and baseline home SBP. Continuous net reclassification improvement (0.53, P ConclusionsA total of 24-hour SBP could be an independent predictor of future home hypertension. Home BP and 24-hour BP can longitudinally influence each other in the long term.

Published
2022

2. (Pro)renin receptor and insulin signalling regulate cell proliferation in MCF-7 breast cancer cells

Author

Shigemitsu Sato, Takuo Hirose, Koji Ohba, Fumihiko Watanabe, Tomoki Watanabe, Kazuya Minato, Akari Endo, Hiroki Ito, Takefumi Mori, and Kazuhiro Takahashi

Subjects
Cell Line, Tumor, Renin, MCF-7 Cells, Humans, Insulin, Female, Breast Neoplasms, General Medicine, Phosphorylation, Proto-Oncogene Proteins c-akt, Molecular Biology, Biochemistry, Cell Proliferation
Abstract

(Pro)renin receptor [(P)RR] is related to both the renin-angiotensin system and V-ATPase with various functions including stimulation of cell proliferation. (P)RR is implicated in the pathophysiology of diabetes mellitus and cancer. Hyperinsulinemia is observed in obesity-related breast cancer. However, the relationship between (P)RR and insulin has not been clarified. We have therefore studied the effect of insulin on (P)RR expression, cell viability and AKT phosphorylation under the conditions with and without (P)RR knockdown. Effects of insulin were studied in a human breast cancer cell line, MCF-7. Cell proliferation assay was performed by WST-8 assay. (P)RR expression was suppressed by (P)RR-specific siRNAs. The treated cells were analysed by western blotting and reverse transcriptase-quantitative polymerase chain reaction analysis. Insulin stimulated proliferation of MCF-7 cells and increased (P)RR protein expression, but not (P)RR mRNA levels. Moreover, autophagy flux was suppressed by insulin. Suppression of (P)RR expression reduced cell number of MCF-7 cells and AKT phosphorylation significantly in both the presence and the absence of insulin, indicating that (P)RR is important for cell viability and AKT phosphorylation. In conclusion, insulin upregulates the level of (P)RR protein, which is important for cell viability, proliferation, AKT phosphorylation and autophagy in breast cancer cells.

Published
2022

3. MO491ASSOCIATION BETWEEN SERUM URIC ACID LEVEL AND CHRONIC KIDNEY DISEASE INCIDENCE STRATIFIED BY SEX IN MIDDLE-AGED ADULTS

Author

Takayoshi Ohkubo, Hirohito Metoki, Takahisa Murakami, Takuo Hirose, Tomoko Muroya, Yukako Tatsumi, Michihiro Satoh, Shingo Nakayama, Takefumi Mori, and Atsushi Hozawa

Subjects
Transplantation, Kidney, medicine.medical_specialty, Proteinuria, business.industry, Incidence (epidemiology), medicine.disease, Gastroenterology, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Nephrology, Internal medicine, medicine, Serum uric acid level, Uric acid, Hyperuricemia, medicine.symptom, business, Kidney disease
Abstract

Background and Aims While previous studies have reported the association between serum uric acid (SUA) and chronic kidney disease (CKD) incidence, the sex differences in this association remain controversial. Therefore, we examined the association between SUA levels and CKD incidence in middle-aged adults stratified by sex using data from a large-scale health check-up. Method We analyzed information from the JMDC database, which included the annual health check-up data of Japanese employees and their dependents aged Results The mean participant age was 44.1 years, and 29.6% were women. The mean SUA levels were 5.9 mg/dL and 4.1 mg/dL in men and women, respectively. During the mean follow-up period of 4.68 years, 12,589 participants developed CKD. The age-standardized incidence rates for CKD were 17.88/17.80 per 1000 person-years in men/women with SUA concentrations of 4.0–4.9 mg/dL, 209.76 per 1000 person-years in men with SUA ≥11.0 mg/dL, and 73.38 per 1000 person-years in women with SUA ≥ 9.0 mg/dL. The fully adjusted HRs (95% confidence interval [CI], P value) for CKD incidence in the groups with SUA concentrations of Conclusion The results of the present study demonstrated an increased risk of CKD in men with SUA concentrations of

Published
2021

4. Urinary Angiotensinogen Excretion Level Is Associated With Elevated Blood Pressure in the Normotensive General Population

Author

Wataru Hida, Sadayoshi Ito, Emiko Sato, Hiroshi Sato, Takefumi Mori, Yoko Nishikiori, Ikuko Oba-Yabana, Michihiro Satoh, Mai Yoshida, and An Yi Wang

Subjects
Male, medicine.medical_specialty, Urinary system, Population, Angiotensinogen, 030232 urology & nephrology, Blood Pressure, 030204 cardiovascular system & hematology, Kidney, medicine.disease_cause, Protein Carbonylation, Renin-Angiotensin System, Excretion, 03 medical and health sciences, 0302 clinical medicine, Japan, Risk Factors, Internal medicine, Renin–angiotensin system, Internal Medicine, medicine, Humans, education, Antihypertensive Agents, Aged, Aged, 80 and over, education.field_of_study, business.industry, Kidney metabolism, Middle Aged, Up-Regulation, Renal Elimination, Cross-Sectional Studies, Endocrinology, Blood pressure, Case-Control Studies, Hypertension, Female, business, Biomarkers, Oxidative stress
Abstract

Background Inflammation, intrarenal renin-angiotensin system (RAS) activation, oxidative stress, and carbonyl stress have been postulated to play a fundamental role in controlling blood pressure. However, little is known about the association among renal RAS activation, carbonyl stress, and blood pressure elevation. Methods We evaluated the relationship between blood pressure elevation and either renal RAS activity or carbonyl stress in the general population (N = 355) in Japan. To minimize the effect of antihypertensive drug therapy, we divided participants into 3 groups (normotensive, hypertensive-with-non-medication, and hypertensive-with-medication). Intrarenal RAS activity and carbonyl stress were indicated by the urinary angiotensinogen (AGT) and carbonyl compound excretion levels, respectively. Results The urinary AGT and carbonyl compound excretion levels were significantly associated with blood pressure. Using a stepwise multiple regression analysis, we found that the urinary AGT excretion levels were strongly associated with blood pressure elevation, compared with inflammation, oxidative stress, and carbonyl stress markers, in all groups. Urinary carbonyl compound excretion was significantly associated with blood pressure in only the hypertensive-without-medication group. Furthermore, blood pressure was significantly increased in these participants, and both the urinary AGT and carbonyl compound levels were high. The urinary AGT excretion levels were strongly associated with elevated blood pressure in normotensive people, and inappropriate renal RAS activity and carbonyl stress independently contributed to the development of hypertension. Conclusions These findings suggest that RAS activation, particularly renal RAS activation exert a fundamental role in the pathogenesis of hypertension in the general population.

Published
2018

5. Association of Aldosterone-to-Renin Ratio With Hypertension Differs by Sodium Intake: The Ohasama Study

Author

Takayoshi Ohkubo, Hirohito Metoki, Takuo Hirose, Kazuhito Totsune, Masahiro Kikuya, Miki Hosaka, Yutaka Imai, Nariyasu Mano, Taku Obara, Ryusuke Inoue, Kei Asayama, Azusa Hara, Megumi Tsubota-Utsugi, Michihiro Satoh, Takefumi Mori, and Haruhisa Hoshi

Subjects
Male, medicine.medical_specialty, Population, Gastroenterology, Plasma renin activity, chemistry.chemical_compound, Japan, Internal medicine, Renin, Renin–angiotensin system, Internal Medicine, medicine, Humans, Longitudinal Studies, Prospective Studies, Salt intake, education, Aldosterone, Aged, Proportional Hazards Models, education.field_of_study, Aldosterone-to-renin ratio, business.industry, Incidence, Hazard ratio, Sodium, Dietary, Middle Aged, Blood pressure, Endocrinology, chemistry, Hypertension, Female, business
Abstract

In cross-sectional studies, the aldosterone-to-renin ratio (ARR) has been reported to be associated with hypertension under conditions of higher sodium intake. The objective of this prospective study was to investigate the association between ARR and the development of hypertension in community residents stratified by dietary sodium intake.From the general population of Ohasama, we obtained plasma renin activity (PRA) and plasma aldosterone concentrations (PACs) for 608 participants (mean age = 57.6 years; 71.4% women) without hypertension at baseline. Using the Cox model, we computed the adjusted hazard ratio (HR) of natural log-transformed ARR (lnARR) for the development of hypertension, defined as blood pressure ≥140/90mm Hg or start of treatment with antihypertensive drugs during follow-up.During a mean follow-up of 6.8 years, 298 participants developed hypertension. The median PRA, PAC, and ARR were 1.2ng/ml/hour, 6.6ng/dl, and 5.5ng/dl per ng/ml/hour, respectively. Each 1 SD increase in lnARR was associated with an increased risk for the development of hypertension in participants overall (HR = 1.18; P = 0.007). In participants with higher sodium intake (median ≥4,102mg/day), a significant association of lnARR with hypertension remained (HR = 1.25; P = 0.009), whereas no significant association was observed in participants with lower sodium intake (P = 0.18). Participants who developed hypertension had significantly lower PRA than those who did not (P = 0.003), despite no differences in PAC (P = 0.91).These results raise the hypothesis that relative aldosterone excess may have a deleterious effect on the development of hypertension by contributing to salt/volume-related hypertension.

Published
2014

6. Aldosterone-to-Renin Ratio as a Predictor of Stroke Under Conditions of High Sodium Intake: The Ohasama Study

Author

Haruhisa Hoshi, Hirohito Metoki, Megumi Utsugi, Michihiro Satoh, Takanao Hashimoto, Takayoshi Ohkubo, Kazuhito Totsune, Taku Obara, Masahiro Kikuya, Atsuhiro Kanno, Takuo Hirose, Azusa Hara, Kei Asayama, Ryusuke Inoue, Hiroshi Satoh, Yutaka Imai, and Takefumi Mori

Subjects
Adult, Male, medicine.medical_specialty, Population, Plasma renin activity, chemistry.chemical_compound, Japan, Risk Factors, Internal medicine, Renin, Internal Medicine, medicine, Humans, Prospective Studies, Sodium Chloride, Dietary, education, Aldosterone, Stroke, Aged, education.field_of_study, Aldosterone-to-renin ratio, business.industry, Incidence, Hazard ratio, Middle Aged, medicine.disease, Endocrinology, Blood pressure, chemistry, Hypertension, Female, business, Low sodium
Abstract

BACKGROUND Aldosterone is thought to have deleterious effects on the cardiovascular system. The aldosterone-to-renin ratio (ARR) is more reproducible than aldosterone levels alone and could be an index for inappropriate aldosterone secretion or activity. We previously reported the apparent relation between ARR and hypertension in subjects with high sodium intake. This prospective study investigated the risk of ARR for a first stroke in a general population stratified by sodium intake. METHODS We obtained plasma renin activity (PRA) and plasma aldosterone concentrations (PAC) for 883 participants aged ≥ 35 years not receiving antihypertensive treatment in the general population of Ohasama (mean age: 59.0 ± 11.3 years; 65.6% women). RESULTS Over a mean of 10.9 follow-up years, 45 strokes occurred. The median PRA, PAC, and ARR were 1.2 ng/ml/h, 6.4 ng/dl, and 5.3 ng/dl per ng/ml/h, respectively. Using Cox regression, we computed hazard ratios adjusted for sex, age, body mass index (BMI), and systolic blood pressure. No association between logARR and stroke was observed in subjects overall. However, in subjects with high sodium intake (≥ median of 4,058 mg/day (salt equivalent, 10.5 g/day)), each 1 s.d. increase in logARR was associated with an increased hazard ratio for stroke (hazard ratio: 1.49, P = 0.04). No significant association was observed in subjects with low sodium intake (P = 0.7). When we repeated all the analyses using logPRA or logPAC, no significant associations were found. CONCLUSION These results suggest that high ARR, that is, relative aldosterone excess, is a predictor for stroke under conditions of high sodium intake.

Published
2012

7. Impaired vasopressin suppression and enhanced atrial natriuretic hormone release following an acute water load in primary aldosteronism

Author

Ken Omata, Takefumi Mori, Takayuki Sahata, Takeharu Funyu, Masahiro Ohta, Tokihisa Kimura, Keishi Abe, Kozo Ota, Tadasu Yamamoto, and Masaru Shoji

Subjects
Adenoma, Adult, Male, Vasopressin, medicine.medical_specialty, Time Factors, Vasopressins, Endocrinology, Diabetes and Metabolism, Urinary system, Adrenal Gland Neoplasms, Drinking, Natriuresis, Diuresis, Urine, Peptide hormone, Endocrinology, Primary aldosteronism, Atrial natriuretic peptide, Internal medicine, Hyperaldosteronism, medicine, Humans, Postoperative Period, Aged, Chemistry, Osmolar Concentration, Adrenalectomy, General Medicine, Middle Aged, medicine.disease, Arginine Vasopressin, Plasma osmolality, Blood, Renal physiology, Potassium, Female, Atrial Natriuretic Factor, hormones, hormone substitutes, and hormone antagonists
Abstract

The release of arginine vasopressin (AVP) and atrial natriuretic hormone (ANH) and their involvement in renal water and electrolyte metabolism in primary aldosteronism in humans were studied. An oral acute water load (20 ml/kg body weight) was given to each of 12 patients before and after surgical removal of their aldosterone-producing adenoma(s). Plasma AVP and ANH were measured simultaneously, and renal water and electrolyte metabolism and tubular functions were determined. The same water load was given to seven normal subjects and the same parameters were determined. In the presence of mineralocorticoid excess before the operation, plasma AVP was relatively low compared with plasma osmolality (Posm), but was not suppressed in response to decreases in Posm after the water load. Baseline plasma ANH was high and increased further after the water load; urinary dilution and diuresis both remained normal. After the operation, baseline plasma AVP was normal and decreased in response to the decrease in Posm after the water load, with normal urinary dilution and diuresis. Baseline plasma ANH was normal, and did not increase after the water load. The ratio of urinary K and Na clearances and distal tubular reabsorption of Na increased before the operation. These results suggest that there are perturbations of AVP and ANH release in primary aldosteronism, despite the normal urinary dilution after a water load.

Published
1997

8. Diabetes mellitus - clinical studies - 1

Author

Hashem Awad, Winfried März, Agung Pranoto, Saraladevi Naicker, Guimian Zou, Sydney S.C. Tang, Qinghua Liu, Antonio Lacquaniti, Branislav Bohus, Quoc C. Van, Ligia Petrica, Mohammad Mohammadi, Silvia Regina Moreira, Jolanta Malyszko, Gabriel Papakakis, Hanna Bachorzewska-Gajewska, Lucia Vesa, Vijaykumar Lingegowda, Dimitris Xydakis, Valentina Galchinskaya, Urmila Anandh, Frank B. Hu, Susumu Ogawa, Sonja Dzikova, Nikolay Goncharov, Pratik Das, Kuntoro, June Fabian, Mohammad Afkhami-Ardekani, Ulrike Raff, Michele Buemi, Richard J. Johnson, Yunhua Liao, Miroslav Mydlik, Harbir Singh Kohli, Dimitrios Athanasopoulos, Weiying Chen, Hui Min Jin, P. S. Semenovykh, Jayakumar Edathedathe Krishnan, Youssef Kadry, Neamatollah Ataei, Thomas M. Beaver, Meraj Tavakkoli, Carmina Muresan, Valentina Donato, Emmanouil Menegakis, Gheorghe Gluhovschi, Weiguo Sui, Maja Milovanceva-Popovska, Yalan Xu, Marina Shestakova, Marc Bauwens, Gary Curhan, Ekaterini Garopoulou, Puneet Sood, Karine R. Sahakyan, Nadereh Rashtchizadeh, Mohamed Hassan Aly, Jacek S. Malyszko, Kwok Wah Chan, Kamal Sud, Haiping Mao, Monica Ahuja, Simohamed Belmouaz, Baranak Safaian, Indro Handojo, Ping Fu, Martin Ritt, Zulkhair Ali, Fatemeh Ataei, Hassan Argani, Boguslaw Poniatowski, Maria Rosaria Fazio, Flaviu Bob, Vera Krane, Sara Moghadasimousavi, Gianna Mastroianni-Kirsztajn, Abbas Madani, Sreelatha Melemadathil, Julie Lin, Shoji Nogae, Florica Gadalean, Wei Chen, Inna Klefortova, Roxana Marian, Yihong Jiang, Javid Safa, Aleksandar Sikole, Cristina Gluhovschi, Guy Touchard, Maria Majdan, Keisuke Nakayama, Virginia Trandafirescu, Tarunveer S. Ahluwalia, Francois Venter, Dorota Suszek, Magdalena Dryglewska, Markus P. Schlaich, Gheorghe Bozdog, Mohamed Ibrahim, Maher Maghrabi, Ott Christian, Kar Neng Lai, Slawomir Dobrzycki, Anil Bhansali, Niveen Shokry, Christos S. Mantzoros, Maria Goretti Polito, Maria Sfakianaki, Salem Ali El-Deeb, Silvia Velciov, Soetjipto, Elvina Tugeeva, Xueqing Yu, Giuseppe Coppolino, Minara Shamkhalova, Caterina Bono, Hang Li, Ivan Topchii, Xuewang Li, Apostolos Papadogiannakis, Eleni Chelioti, Nader Nouri-Majalan, Ilma Modanez, Christiane Drechsler, Frank Bridoux, Yu Pan, Julie Teynie, Kristine E. Lee, Amy Shan Cheng, Vlado Nikolov, Victor Dumitrascu, Bhagwan Dass, Takefumi Mori, Konstantinos Kostakis, Tsuneo Ishizuka, Eberhard Ritz, Konstantinos Papachristoforou, Dimitrios Kolokythas, Sorin Giju, Calina Ianculescu, Katarina Derzsiova, Tanqi Lou, Seyed Taher Esfahani, Davide Bolignano, Samy Hadjaj, Nariman Nezami, Maxim Petrica, Catalin Jianu, Jian Chen, Despoina Dimitriadou, Sadayoshi Ito, Christoph Wanner, Adrian Vlad, Michiko Shimada, Hequn Zou, A. Ahsan Ejaz, Roland E. Schmieder, Mohammad Yogiantoro, Natalia Trubitsyna, Kazuhiro Nako, Vesna Ristovska, Amir Ghorbanihaghjo, Wenti Che, Masaaki Nakayama, Mamoru Satoh, Jinli Zhang, Joseph Leung, Ury Buziashvili, Sorin Ursoniu, Barbara E.K. Klein, Yubing Wen, Loretta Y.Y. Chan, Madhu Khullar, Tessei Yamao, Ronald Klein, Markus P. Schneider, Prokopis Papazafeiris, Osama El-Nabarawy, and Hui Y. Lan

Subjects
Transplantation, medicine.medical_specialty, Nephrology, business.industry, Internal medicine, Diabetes mellitus, medicine, business, medicine.disease
Published
2009

9. Diabetes mellitus - clinical studies - 2

Author

A. Sattar, István Wittmann, Domenico Corradi, M. Haapio, Bernhard M.W. Schmidt, Susumu Ogawa, Ruth Mitchell, Carlos Alberto Mayora Aita, Colin J. Meyer, Peter-Rene Mertens, Esztella Mikolás, P. Miarka, Tatjana Cvetkovic, Ling Li, Georgios Hadjigeorgiou, J.A. Kellum, JoséMauro Vieira, Pál Brasnyó, Vuddhidej Ophascharoensuk, Hiroshi Sato, Eszter Fehér, Mártóon Mohás, Julia B. Lewis, Yusuke Osaki, Ulrike Raff, Tuneo Ishizuka, Mirela Liana Gliga, Sadayoshi Ito, Maximilian von Eynatten, Augusto Vaglio, Spyridon Arampatzis, Ramesh Chandra Vyasam, F. Nurhan Ozdemir, Jutalai Tanterdtham, M. Walus-Miarka, Marcus Baumann, Laura Pavone, Ausilia Maione, Carlos Kornhauser, Weiqian Sun, Renate Koppensteiner, Myrto Giannopoulou, Grigore Aloiziu Dogaru, Nestor Schor, August Heidland, Srilatha Vadlamudi, C. Argyropoulos, Peter Boor, Somkiat Vasuvattakul, L. Weissfeld, Alessandra Palmisano, Gloria Barbosa-Sabaner, M. Stompor, Jae Sung Lee, Demet Yavuz, Vladimir Arandjelovic, Ioanna Chronopoulou, Paisal Parichatikanond, Maria Goretti Polito, Takashi Nakamichi, Masanori Ito, Denise H.M.P. Diniz, Katarína Šebeková, T. Grodzicki, Bi-Cheng Liu, Toshio Mochizuki, Federico Alberici, Roberto Zatz, Jamille Godoy Mendes, Pingyan Shen, M. de Cal, Qi Long, Tadayuki Okumoto, M. Unruh, Nan Chen, Kraiwiporn Kiattisunthorn, Predrag Vlahovic, Gerit-Holger Schernthaner, Carlo Salvarani, Ilma Modanez, Per M. Humpert, Stacey Ruiz, Peggy Gao, Boonyarit Cheunsuchon, M. Batur Canoz, Lei Yan, Guntram Schernthaner, Dietmar Zdunek, Maria Dardioti, Claudio Ronco, Simeone Andrulli, Silvia M. Titan, Hans-Henrik Parving, Mohammed Bashir, Roland E. Schmieder, Florian Hoellerl, Hideyuki Inoue, Kristína Klenovicsová, Daniel Cruz, W. Sulowicz, Norman K. Hollenberg, Antonio Nicolucci, Ioannis Stefanidis, Donal O'Shea, Paulo C. Fortes, Vladislav Stefanovic, Seiji Hashimoto, Edmund J. Lewis, Ines Casazza, F. Nalesso, Wattana B. Watanapa, Rosario Foti, Sasa Milenkovic, Sherwyn Schwartz, Gianna Mastroianni-Kirsztajn, Takayuki Yamada, Judit Cseh, Athakorn Kirakul, M. Krzanowski, Johannes Mann, Efthymios Dardiotis, Jeffrey G. Supko, T J Cawood, Angelika Bierhaus, Chiara Grasselli, Cornelia Zumpe, E. Chowaniec, Wen Zhang, Hyeong Cheon Park, Takuma Hosoya, Mihai Gliga, Frederik Persson, Pablo Pergola, Erika Oliveira da Silva, Jicheng Lv, Chien-Te Lee, Tasuku Nagasawa, Noemi Gutierrez-Romero, Alberto Pesci, Karsten Kreuer, Sung Jin Moon, Douglas Denham, Roberto Pecoits-Filho, Hong Zhang, Kriengsak Vareesangthip, B. Ciepiela, Miguel C. Riella, A.A. House, Ke-Dan Cai, Terry Ting-Yu Chiou, Silvia Regina Moreira, Ravi Raju Tatapudi, Craig A. Hurwitz, Davide Martorana, Peter P. Nawroth, Giovanni F.M. Strippoli, István András Szijártó, Jung Eun Lee, Inés Birlouez-Aragon, Takao Koike, Hong Ren, kos Mérei, Ampica Mangklabruk, Gabriella Moroni, Hai-yan Wang, Veronika Somoza, Thomas K. Schwarz, Johanna Brix, Branka Mitic, Zi-Lin Sun, Saori Nishio, Sufang Shi, Sung Kyu Ha, Xiaoxia Pan, Ravi Shankar Subramaniam, Georg Hess, P. Lentini, Prasad Gullipalli, Siren Sezer, Sankar D. Navaneethan, Soung Rok Sim, Marcel Roos, Rui Toledo Barros, Uwe Heemann, Jennifer Brady, Kazuhiro Nako, Markus P. Schneider, Barbara Murray, Tibor Vas, M. Dubiel, Giselle Saavedra, Carlo Buzio, Vidojko Djordjevic, Rue-Tsuan Liu, Daisuke Ito, Vassilios Liakopoulos, T. Stompor, Suchai Sritippayawan, Carmen Caldararu, and Takefumi Mori

Subjects
Transplantation, medicine.medical_specialty, Nephrology, business.industry, Internal medicine, Diabetes mellitus, medicine, business, medicine.disease
Published
2009

10. Experimental pathology - 1

Author

Sreenivas Reddy, Kerstin Benz, Flavia Gomes Machado, Takahiro Masuda, Andrea Hartner, Jingjing Chai, Giancarlo Viberti, Christian Hugo, Anil Bhanudas Gaikwad, Toshio Miyata, Sara Ramírez-Rubio, Atsuko Mizuno, Kyoko Takahashi, Holger Haegele, Takefumi Mori, Hitoshi Ando, Song Rong, Bernd Klanke, Antonio Dal Canton, Ram Sharma, Anthea Hayward, Roberto Zatz, Nada Cordasic, Hyung Eun Yim, Anne-Cécile Huby, Koji Hashimoto, Michael S. Goligorsky, Julia Lichtnekert, Luciana Maria Ferreira Carvalho, Giovanni Camussi, Taeko Hashimoto, Fujio Shimizu, Toshiro Fujita, Rui Alves, Miłosz Zarzecki, Takashi Oite, Benedetta Bussolati, Sarah Louise Verhardt, Honglan Piao, Makoto Uchiyama, Yoshitaka Iwazu, Li Ying, Jan U. Becker, Marie-Luise Gross, Ayako Sato, JunWu Dong, Shigeru Sato, Miguel Arévalo, Miroslava Kupraszewicz-Hutzler, Tomoko Okamoto, Katsuyuki Tanabe, Hirofumi Makino, Rainer Wachtveitl, Stefania Bruno, Pasquale Esposito, Zhangsuo Liu, Sachiko Yamada, Kazuhiro Shiizaki, Nadine Hainz, Reinhard E. Voll, Eberhard Ritz, Claudia R. Sena, Mari Tanaka, Masaaki Nameta, Juergen Floege, Kohei Miyake, Alessandra Dei Cas, Zhai Shaina, Hiroshi Sato, Hiroko Yamasaki, María Maiques, P. Santos, Daniele Canale, Hongrui Dong, Yutaka Harita, Takashi Ioka, Yukiko Nozawa, Jia Liyan, In Sun Bae, Tobias B. Huber, Elisa Gabanti, Toshifumi Aoyama, Ralf Weiskirchen, Jeffrey B. Kopp, Hideki Takano, Satoshi Kinugasa, Bernhard Nieswandt, Bernard Perbal, Makoto Higuchi, Kerstin Amann, Susanne Weber, P. Garrido, Wolfgang Rascher, Kathleen M. Caron, Björn Hartleben, Zoe Webster, Maria-Pia Rastaldi, Sufyan Ali Sayyed, Gi Dong Han, Yuki Oyama, Bernd Hohenstein, Antoni Wystrychowski, Nadia T. Yanakieva-Georgieva, Motoko Yanagita, Kouju Kamata, Nozomu Yamanaka, Seong Eun Kim, Kulbhushan Tikoo, Karen Price, Atsushi Fukatsu, Naoko Miyauchi, Shokichi Naito, Greg H. Tesch, Jose-Miguel López-Novoa, Virginia J. Savin, Kirstin Winkelmann, Jean-Claude Dussaule, Hermann Haller, Masaomi Nangaku, Julie R. Ingelfinger, Gi Young Jang, Yohei Maeshima, Won-Suk An, Hiroko Koike, Christoph Daniel, Ki Hyun Kim, Nosratola D. Vaziri, Joo Won Lee, Shinji Kitamura, Bianca Helena Ventura Fernandes, Michael Leitges, Jian Yao, Takashi Nakamichi, Oliver Smithies, Toru Kita, Erawan Borkham-Kamphorst, Mohamed R. Daha, Kee Hwan Yoo, Clarice Kazue Fujihara, Tadao Akizawa, Ellen T. McCarthy, Sven Klussmann, Liu Maodong, Claudia R.C. van Roeyen, Hiroshi Kawachi, Mario Schiffer, Michael Wiesener, Hyun-ju Kim, Young Sook Hong, Fadia A. Kamal, Akihiro Tojo, Tatsuyo Nasu, Takashi Ehara, Denise Maria Avancini Costa Malheiros, Francesco Frassoni, Selma Benito, Sadayoshi Ito, Tamaki Karasawa, Shigeaki Muto, Hiromi Tazaki, David J. Nikolic-Paterson, David A. Long, Chiara Teresa Balenzano, Onkar P. Kulkarni, Marcin Adamczak, Kirsten Neubert, F. Teixeira, Giovanni Piotti, Adrian S. Woolf, Elizabete P.B. Poppi, Karl F. Hilgers, Ken Lerea, Hitoshi Sugiyama, Luigi Gnudi, Hongliang Rui, B. Parada, Hidekazu Shigematsu, Mayumi Tomita, Hans-Joachim Anders, Li Ya, Trinidad Parra-Cid, Dirk Eulberg, Uta Kunter, F. Reis, Takanori Shibata, Peter Boor, Maristela L. Onozato, Giulia Bedino, Andrea Lüdke, Makoto Suzuki, Shi Yonghong, Fernando Pérez-Barriocanal, Tammo Ostendorf, Myriam Calvino-Fernández, Teresa Rampino, Zhang Yanling, Gabriel de Arriba, Daisuke Saito, Wang Baoxing, Julie Toubas, Reiko Inagi, Francesca Bosio, Mythily Sachchithananthan, Tetsuo Morioka, Dominique Chansel, Yuji Kamijo, Atsushi Hirano, Chiharu Ito, Cristina Grange, Giuseppe Paolo Segoloni, Masayuki Iyoda, Lyn Hurst, M. Teresa Grande, Eiji Kusano, Takahisa Kawakami, Sonja Hess, Togo Aoyama, Yoshiki Sakai, Yipu Chen, Yuko Watanabe, Rudy Bilous, Christos Chatziantoniou, Christos E. Chadjichristos, Mukut Sharma, Marilena Gregorini, SuLe Htay, Adalberto Ibatici, Toshinobu Sato, Camilla Fanelli, A. Almeida, Shinichi Okada, Kyu-Hyang Cho, Atsuko Y. Higashi, Susanne B. Thomas, Kathryn White, and Andrzej Wiecek

Subjects
Transplantation, Pathology, medicine.medical_specialty, Nephrology, business.industry, medicine, Experimental pathology, business
Published
2009

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