1. Antibody response to SARS-CoV-2 infection is not associated with Post-COVID-19 Syndrome in healthcare workers
- Author
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Pereira, Christopher, Harris, Benjamin H L, Di Giovannantonio, Matteo, Rosadas, Carolina, Short, Charlotte-Eve, Quinlan, Rachael, Sureda-Vives, Macià, Fernandez, Natalia, Day-Weber, Isaac, Khan, Maryam, Marchesin, Federica, Katsanovskaja, Ksenia, Parker, Eleanor, Taylor, Graham P, Tedder, Richard S, McClure, Myra O, Dani, Melanie, and Fertleman, Michael
- Subjects
Adult ,Male ,Post–COVID-19 Syndrome ,Anosmia ,Health Personnel ,Respiratory Tract Diseases ,Antibodies, Viral ,Microbiology ,Cohort Studies ,Imperial Hybrid DABA ,Young Adult ,Nasopharynx ,Surveys and Questionnaires ,Humans ,Healthcare workers ,Longitudinal Studies ,Post-COVID-19 Syndrome ,multidisciplinary team ,Fatigue ,11 Medical and Health Sciences ,Aged ,multi-disciplinary team ,SARS-CoV-2 ,Brief Report ,Headache ,COVID-19 ,Syndrome ,Long-COVID ,Middle Aged ,06 Biological Sciences ,United Kingdom ,humanities ,AcademicSubjects/MED00290 ,Female - Abstract
It is currently unknown how post-COVID-19 syndrome (PCS) may affect those infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This longitudinal study includes healthcare staff who tested positive for SARS-CoV-2 between March and April 2020, with follow-up of their antibody titers and symptoms. More than half (21 of 38) had PCS after 7-8 months. There was no statistically significant difference between initial reverse-transcription polymerase chain reaction titers or serial antibody levels between those who did and those who did not develop PCS. This study highlights the relative commonality of PCS in healthcare workers and this should be considered in vaccination scheduling and workforce planning to allow adequate frontline staffing numbers.
- Published
- 2021