23 results on '"Kastelein, John J.P."'
Search Results
2. Can we afford not to screen for FH?
3. Selection of individuals for genetic testing for familial hypercholesterolaemia: development and external validation of a prediction model for the presence of a mutation causing familial hypercholesterolaemia
4. Safety and efficacy of LY3015014, a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 (PCSK9): a randomized, placebo-controlled Phase 2 study
5. ODYSSEY FH I and FH II: 78 week results with alirocumab treatment in 735 patients with heterozygous familial hypercholesterolaemia
6. Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype–phenotype relationship, and clinical outcome
7. Clinical implications of JUPITER in a contemporary European population: the EPIC-Norfolk prospective population study
8. Diagnosis and treatment of familial hypercholesterolaemia
9. C-reactive protein and cholesterol are equally strong predictors of cardiovascular risk and both are important for quality clinical care
10. Antisense oligonucleotides for the treatment of dyslipidaemia
11. Mipomersen, an apolipoprotein B synthesis inhibitor, lowers low-density lipoprotein cholesterol in high-risk statin-intolerant patients: a randomized, double-blind, placebo-controlled trial
12. Advances in genetics show the need for extending screening strategies for autosomal dominant hypercholesterolaemia
13. Cardiovascular risk in relation to functionality of sequence variants in the gene coding for the low-density lipoprotein receptor: a study among 29 365 individuals tested for 64 specific low-density lipoprotein-receptor sequence variants
14. Vascular effects and safety of dalcetrapib in patients with or at risk of coronary heart disease: the dal-VESSEL randomized clinical trial
15. Efficacy of apolipoprotein B synthesis inhibition in subjects with mild-to-moderate hyperlipidaemia
16. A frequent variant in the ABCA1 gene is associated with increased coronary heart disease risk and a better response to statin treatment in familial hypercholesterolemia patients
17. Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia
18. Gene-load score of the renin–angiotensin–aldosterone system is associated with coronary heart disease in familial hypercholesterolaemia
19. Paraoxonase genotype and carotid intima???media thickness in children with familial hypercholesterolemia
20. Functional interaction between −629C/A, −971G/A and −1337C/T polymorphisms in the CETP gene is a major determinant of promoter activity and plasma CETP concentration in the REGRESS Study
21. The realities of dyslipidaemia: what do the studies tell us?
22. Predictive value of mild, residual descending aortic narrowing for blood pressure and vascular damage in patients after repair of aortic coarctation
23. The apolipoprotein(a) kringle IV repeats which differ from the major repeat kringle are present in variably-sized isoforms
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