1. Interferon-Gamma Release Assays and Pediatric Public Health Tuberculosis Screening: The San Francisco Program Experience 2005 to 2008
- Author
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Olivia Chang Tran, Shamim Islam, Jennifer Grinsdale, Christine S Ho, L. Masae Kawamura, and Julie Higashi
- Subjects
Male ,medicine.medical_specialty ,Pediatrics ,Tuberculosis ,Adolescent ,Concordance ,Tuberculin ,Article ,QuantiFERON ,03 medical and health sciences ,0302 clinical medicine ,030225 pediatrics ,Epidemiology ,medicine ,Humans ,Mass Screening ,030212 general & internal medicine ,Child ,Retrospective Studies ,Latent tuberculosis ,Tuberculin Test ,business.industry ,Public health ,Infant ,General Medicine ,bacterial infections and mycoses ,medicine.disease ,Vaccination ,Infectious Diseases ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Immunology ,Female ,San Francisco ,business ,Interferon-gamma Release Tests - Abstract
BACKGROUND. Interferon-gamma release assay utilization in pediatric tuberculosis (TB) screening is limited by a paucity of longitudinal experience, particularly in low-TB burden populations. METHODS. We conducted a retrospective review of QuantiFERON (QFT)-TB Gold results in San Francisco children from 2005 to 2008. Concordance with the tuberculin skin test (TST) was analyzed for a subset of children. Progression to active disease was determined through San Francisco and California TB registry matches. RESULTS. Of 1092 children
- Published
- 2014
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