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Your search keyword '"Bhak, Jong"' showing total 17 results
Start Over Author "Bhak, Jong" Publisher oxford university press (oup)
17 results on '"Bhak, Jong"'

1. Korea4K: whole genome sequences of 4,157 Koreans with 107 phenotypes derived from extensive health check-ups

Author

Jeon, Sungwon, primary, Choi, Hansol, additional, Jeon, Yeonsu, additional, Choi, Whan-Hyuk, additional, Choi, Hyunjoo, additional, An, Kyungwhan, additional, Ryu, Hyojung, additional, Bhak, Jihun, additional, Lee, Hyeonjae, additional, Kwon, Yoonsung, additional, Ha, Sukyeon, additional, Kim, Yeo Jin, additional, Blazyte, Asta, additional, Kim, Changjae, additional, Kim, Yeonkyung, additional, Kang, Younghui, additional, Woo, Yeong Ju, additional, Lee, Chanyoung, additional, Seo, Jeongwoo, additional, Yoon, Changhan, additional, Bolser, Dan, additional, Biro, Orsolya, additional, Shin, Eun-Seok, additional, Kim, Byung Chul, additional, Kim, Seon-Young, additional, Park, Ji-Hwan, additional, Jeon, Jongbum, additional, Jung, Dooyoung, additional, Lee, Semin, additional, and Bhak, Jong, additional

Published
2024
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6. Comparative analysis of 7 short-read sequencing platforms using the Korean Reference Genome: MGI and Illumina sequencing benchmark for whole-genome sequencing

Author

Kim, Hak-Min, primary, Jeon, Sungwon, additional, Chung, Oksung, additional, Jun, Je Hoon, additional, Kim, Hui-Su, additional, Blazyte, Asta, additional, Lee, Hwang-Yeol, additional, Yu, Youngseok, additional, Cho, Yun Sung, additional, Bolser, Dan M, additional, and Bhak, Jong, additional

Published
2021
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7. Defining the mutation signatures of DNA polymerase θ in cancer genomes

Author

Hwang, Taejoo, primary, Reh, Shelley, additional, Dunbayev, Yerkin, additional, Zhong, Yi, additional, Takata, Yoko, additional, Shen, Jianjun, additional, McBride, Kevin M, additional, Murnane, John P, additional, Bhak, Jong, additional, Lee, Semin, additional, Wood, Richard D, additional, and Takata, Kei-ichi, additional

Published
2020
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8. Whole-genome, transcriptome, and methylome analyses provide insights into the evolution of platycoside biosynthesis in Platycodon grandiflorus, a medicinal plant

Author

Kim, Jungeun, primary, Kang, Sang-Ho, additional, Park, Sin-Gi, additional, Yang, Tae-Jin, additional, Lee, Yi, additional, Kim, Ok Tae, additional, Chung, Oksung, additional, Lee, Jungho, additional, Choi, Jae-Pil, additional, Kwon, Soo-Jin, additional, Lee, Keunpyo, additional, Ahn, Byoung-Ohg, additional, Lee, Dong Jin, additional, Yoo, Seung-il, additional, Shin, In-Gang, additional, Um, Yurry, additional, Lee, Dae Young, additional, Kim, Geum-Soog, additional, Hong, Chang Pyo, additional, Bhak, Jong, additional, and Kim, Chang-Kug, additional

Published
2020
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11. The Draft Genome of an Octocoral, Dendronephthya gigantea

Author

Jeon, Yeonsu, primary, Park, Seung Gu, additional, Lee, Nayun, additional, Weber, Jessica A, additional, Kim, Hui-Su, additional, Hwang, Sung-Jin, additional, Woo, Seonock, additional, Kim, Hak-Min, additional, Bhak, Youngjune, additional, Jeon, Sungwon, additional, Lee, Nayoung, additional, Jo, Yejin, additional, Blazyte, Asta, additional, Ryu, Taewoo, additional, Cho, Yun Sung, additional, Kim, Hyunho, additional, Lee, Jung-Hyun, additional, Yim, Hyung-Soon, additional, Bhak, Jong, additional, and Yum, Seungshic, additional

Published
2019
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12. MBRS-25. GENOMIC ANALYSES REVEALED RADIATION-INDUCED GLIOBLASTOMA IN A SUBSET OF RECURRENT MEDULLOBLASTOMAS

Author

Phi, Ji Hoon, primary, Park, Ae Kyung, additional, Lee, Semin, additional, Baek, In-Pyo, additional, Kim, Eun-Hye, additional, Park, Hee-Chul, additional, Kim, Byung Chul, additional, Bhak, Jong, additional, Park, Sung-Hye, additional, Lee, Ji Yeoun, additional, Wang, Kyu-Chang, additional, Kim, Dong-Seok, additional, Shim, Kyun Won, additional, Kim, Se Hoon, additional, Kim, Chae-Yong, additional, and Kim, Seung-Ki, additional

Published
2018
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13. iAnn: an event sharing platform for the life sciences

Author

Jimenez, Rafael C., primary, Albar, Juan P., additional, Bhak, Jong, additional, Blatter, Marie-Claude, additional, Blicher, Thomas, additional, Brazas, Michelle D., additional, Brooksbank, Cath, additional, Budd, Aidan, additional, De Las Rivas, Javier, additional, Dreyer, Jacqueline, additional, van Driel, Marc A., additional, Dunn, Michael J., additional, Fernandes, Pedro L., additional, van Gelder, Celia W. G., additional, Hermjakob, Henning, additional, Ioannidis, Vassilios, additional, Judge, David P., additional, Kahlem, Pascal, additional, Korpelainen, Eija, additional, Kraus, Hans-Joachim, additional, Loveland, Jane, additional, Mayer, Christine, additional, McDowall, Jennifer, additional, Moran, Federico, additional, Mulder, Nicola, additional, Nyronen, Tommi, additional, Rother, Kristian, additional, Salazar, Gustavo A., additional, Schneider, Reinhard, additional, Via, Allegra, additional, Villaveces, Jose M., additional, Yu, Ping, additional, Schneider, Maria V., additional, Attwood, Teresa K., additional, and Corpas, Manuel, additional

Published
2013
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14. Automatic synchronization and distribution of biological databases and software over low-bandwidth networks among developing countries

Author

Sangket, Unitsa, primary, Phongdara, Amornrat, additional, Chotigeat, Wilaiwan, additional, Nathan, Darran, additional, Kim, Woo-Yeon, additional, Bhak, Jong, additional, Ngamphiw, Chumpol, additional, Tongsima, Sissades, additional, Khan, Asif M., additional, Lin, Honghuang, additional, and Tan, Tin Wee, additional

Published
2007
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16. Sequence-Level Analysis of the Diploidization Process in the TriplicatedFLOWERING LOCUS CRegion ofBrassica rapa

Author

Yang, Tae-Jin, primary, Kim, Jung Sun, additional, Kwon, Soo-Jin, additional, Lim, Ki-Byung, additional, Choi, Beom-Soon, additional, Kim, Jin-A, additional, Jin, Mina, additional, Park, Jee Young, additional, Lim, Myung-Ho, additional, Kim, Ho-Il, additional, Lim, Yong Pyo, additional, Kang, Jason Jongho, additional, Hong, Jin-Han, additional, Kim, Chang-Bae, additional, Bhak, Jong, additional, Bancroft, Ian, additional, and Park, Beom-Seok, additional

Published
2006
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17. Chromosome-scale assembly comparison of the Korean Reference Genome KOREF from PromethION and PacBio with Hi-C mapping information

Author

Semin Lee, Yun Sung Cho, Changjae Kim, Hui-Su Kim, Asta Blazyte, Sungwon Jeon, Jong Bhak, Jung-Eun Kim, Yeon Kyung Kim, Andrea Manica, Bhak, Jong [0000-0002-4228-1299], Apollo - University of Cambridge Repository, and Manica, Andrea [0000-0003-1895-450X]

Subjects
Cost-Benefit Analysis, 0206 medical engineering, PromethION, Sequence assembly, Health Informatics, 02 engineering and technology, Computational biology, Biology, Data Note, Genome, Structural variation, Korean reference genome, 03 medical and health sciences, Contig Mapping, KOREF, Hi-C, Databases, Genetic, Republic of Korea, Chromosomes, Human, Humans, 030304 developmental biology, 0303 health sciences, Contig, Whole Genome Sequencing, High-Throughput Nucleotide Sequencing, Single Molecule Imaging, Computer Science Applications, single-molecule sequencing, nanopore sequencing, Human genome, Nanopore sequencing, 020602 bioinformatics, Single molecule real time sequencing, Reference genome
Abstract

Background Long DNA reads produced by single-molecule and pore-based sequencers are more suitable for assembly and structural variation discovery than short-read DNA fragments. For de novo assembly, Pacific Biosciences (PacBio) and Oxford Nanopore Technologies (ONT) are the favorite options. However, PacBio's SMRT sequencing is expensive for a full human genome assembly and costs more than $40,000 US for 30× coverage as of 2019. ONT PromethION sequencing, on the other hand, is 1/12 the price of PacBio for the same coverage. This study aimed to compare the cost-effectiveness of ONT PromethION and PacBio's SMRT sequencing in relation to the quality. Findings We performed whole-genome de novo assemblies and comparison to construct an improved version of KOREF, the Korean reference genome, using sequencing data produced by PromethION and PacBio. With PromethION, an assembly using sequenced reads with 64× coverage (193 Gb, 3 flowcell sequencing) resulted in 3,725 contigs with N50s of 16.7 Mb and a total genome length of 2.8 Gb. It was comparable to a KOREF assembly constructed using PacBio at 62× coverage (188 Gb, 2,695 contigs, and N50s of 17.9 Mb). When we applied Hi-C–derived long-range mapping data, an even higher quality assembly for the 64× coverage was achieved, resulting in 3,179 scaffolds with an N50 of 56.4 Mb. Conclusion The pore-based PromethION approach provided a high-quality chromosome-scale human genome assembly at a low cost with long maximum contig and scaffold lengths and was more cost-effective than PacBio at comparable quality measurements.

Published
2020
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