1. Wheat grain immunofluorescent antibodies as an indication of gluten sensitivity?
- Author
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Kirsti Kalimo and Eeva Vainio
- Subjects
Adult ,Male ,Pathology ,medicine.medical_specialty ,Adolescent ,Glutens ,Dermatitis Herpetiformis ,Fluorescent Antibody Technique ,Wheat gluten ,Gluten sensitivity ,Dermatology ,Immunofluorescence ,Antibodies ,Dermatitis herpetiformis ,medicine ,Humans ,Child ,Triticum ,Aged ,Skin Tests ,Wheat grain ,biology ,medicine.diagnostic_test ,business.industry ,Circulating antibodies ,food and beverages ,Atopic dermatitis ,Middle Aged ,medicine.disease ,Immunoglobulin G ,Immunology ,biology.protein ,Female ,Antibody ,business ,Food Hypersensitivity - Abstract
SUMMARY An immunofluorescence method using whole sections of wheat grains as the substrate was applied to detect circulating antibodies to wheat gluten in dermatitis herpetiformis patients and in controls. Only IgG class antibodies were detected. From dermatitis herpetiformis patients 22% had these antibodies as had 22% of the atopic dermatitis group. Among the controls who had no skin problems 12% were faintly positive. It is evident that the test as such is non-specific and does not have diagnostic significance in dermatitis herpetiformis.
- Published
- 1980
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