22 results on '"Stevens MF"'
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2. Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway.
3. Investigations on the biological properties of the lipophilic DHFR-inhibitory benzoprims reveal non-folate modes of action and opportunities for anti-cancer drug design.
4. Antitumour imidazotetrazines. Part 37. Conjugation of the DNA major-groove alkylating imidazotetrazine mitozolomide to peptide motifs recognizing the minor groove.
5. Antitumour polycyclic acridines. Part 4. Physico-chemical studies on the interactions between DNA and novel tetracyclic acridine derivatives.
6. Antitumour polycyclic acridines. Part 2. Physicochemical studies on the interactions between DNA and novel polycyclic acridine derivatives.
7. Structural studies on bioactive compounds. Part 26. Hydrogen bonding in the crystal structure of the N-methylformamide solvate of the immunomodulatory agent 2-amino-5-bromo-6-phenylpyrimidin-4-one (bropirimine): implications for the design of novel anti-tumour strategies.
8. Structural studies on bioactive compounds. Part 27. Chemistry of the immunomodulatory agent bropirimine.
9. Structural studies on bio-active compounds. Part 21. Acid-promoted debenzylations in antitumour 2,4-diamino-5-[4-(N-alkylbenzylamino)-3-nitrophenyl]-6-ethylp yrimidines.
10. Structural studies on bio-active compounds. Part XIV. Molecular modelling of the interactions between pentamidine and DNA.
11. Structural studies on bio-active compounds. Part 16. Synthesis and properties of sterically-constrained analogues of methylbenzoprim, a new dihydrofolate reductase inhibitor.
12. Anti-tumour imidazotetrazines. Part XXI. Mitozolomide and temozolomide: probes for the major groove of DNA.
13. Photodegradation of solutions of the antitumour drug DTIC [proceedings].
14. The aromatic azido group in anti-cancer drug design: application in the development of novel lipophilic dihydrofolate reductase inhibitors.
15. A new light on the photo-decomposition of the antitumour drug DTIC.
16. alpha-Hydroxylated triazenes: potential active metabolites of anti-tumour dimethyltriazenes [proceedings].
17. The biological and chemical properties of 4-azidobenzenesulphonamide ('azidosulphanilamide') [proceedings].
18. Search for drug interactions between the antitumour agent DTIC and other cytotoxic agents [proceedings].
19. Structural studies on bio-active compounds. Part 9. 2,4-Diamino-6-azidoquinazoline hydrochloride.
20. Proceedings: Inhibition of cholinesterase activity by two methylacridinium compounds.
21. Chemical oxidation and in vitro metabolism of 1-(4-chlorophenylazo) piperidine and its heteroalicyclic analogues [proceeding].
22. Photolysis of a methaqualone metabolite.
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