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1. Frequency of use and cost in Japan of first-line palliative chemotherapies for recurrent or metastatic squamous cell carcinoma of the head and neck.

2. Association of the modified Glasgow prognostic score and prognostic nutritional index with duration of oral anamorelin administration in patients with cancer cachexia: a retrospective cohort study.

3. α2-Antiplasmin is associated with macrophage activation and fibrin deposition in a macrophage activation syndrome mouse model.

5. Clinical response of pancreatic cancer bearing a germline BRCA2 p.I3169M fs*48 variant for platinum-based drug and PARP inhibitor.

6. Curcumin analog GO-Y030 inhibits tumor metastasis and glycolysis.

7. Associations of Diabetic Retinopathy Severity With High Ambulatory Blood Pressure and Suppressed Serum Renin Levels.

8. Crucial role of iron in epigenetic rewriting during adipocyte differentiation mediated by JMJD1A and TET2 activity.

9. Lymph-node metastasis from gastric adenocarcinoma in a patient bearing a germ line missense variant MSH2 c.1808A > T (Asp603Val) responds to the immune checkpoint inhibitor pembrolizumab.

10. A novel Lynch syndrome pedigree bearing germ-line MSH2 missense mutation c.1808A>T (Asp603Val).

11. Effectiveness of subcutaneous tocilizumab in refractory adult Still's disease: report of three cases and a review of the literature.

12. Structural insight and stability of TNFR-Fc fusion protein (Etanercept) produced by using transgenic silkworms.

13. Lung adenocarcinoma in a patient with Li-Fraumeni syndrome bearing a novel germ-line mutation, TP53R333Vfs*12.

14. PROPOSAL FOR LOCAL DIAGNOSTIC REFERENCE LEVELS IN GENERAL RADIOGRAPHY IN JAPAN.

15. l-Leucine influx through Slc7a5 regulates inflammatory responses of human B cells via mammalian target of rapamycin complex 1 signaling.

16. Ability of plant pathogenic fungi Gibberella fujikuroi and Fusarium commune to react with airborne methyl jasmonate.

17. Synonymous but Not Silent: A Synonymous VHL Variant in Exon 2 Confers Susceptibility to Familial Pheochromocytoma and von Hippel-Lindau Disease.

18. Single incision laparoscopic surgery (SILS) for Meckel's diverticulum.

20. Adaptor functions of the Ca 2+ -binding protein ALG-2 in protein transport from the endoplasmic reticulum.

21. Obesity as a Key Factor Underlying Idiopathic Hyperaldosteronism.

22. Clinical Characteristics and Postoperative Outcomes of Primary Aldosteronism in the Elderly.

23. Significance of Computed Tomography and Serum Potassium in Predicting Subtype Diagnosis of Primary Aldosteronism.

24. Large-vessel involvement in granulomatosis with polyangiitis successfully treated with rituximab: A case report and literature review.

25. Whole-pelvic radiotherapy with spot-scanning proton beams for uterine cervical cancer: a planning study.

26. The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline.

27. Use of bicarbonate buffer systems for dissolution characterization of enteric-coated proton pump inhibitor tablets.

28. Maternal dietary imbalance between omega-6 and omega-3 polyunsaturated fatty acids impairs neocortical development via epoxy metabolites.

29. Case Report: Nodule Development From Subcapsular Aldosterone-Producing Cell Clusters Causes Hyperaldosteronism.

30. Successful visualization of an indeterminate hepatic metastasis from thyroid carcinoma using contrast-enhanced CT and contrast-enhanced ultrasound.

31. Effects of heat-killed Lactobacillus pentosus S-PT84 on postprandial hypertriacylglycerolemia in rats.

32. VPS37 isoforms differentially modulate the ternary complex formation of ALIX, ALG-2, and ESCRT-I.

33. Mammalian ESCRT-III-related protein IST1 has a distinctive met-pro repeat sequence that is essential for interaction with ALG-2 in the presence of Ca2+.

34. Identification of phosphorylation sites in the C-terminal region of charged multivesicular body protein 1A (CHMP1A).

35. Effect of KCNJ5 mutations on gene expression in aldosterone-producing adenomas and adrenocortical cells.

36. Identification of the P-body component PATL1 as a novel ALG-2-interacting protein by in silico and far-Western screening of proline-rich proteins.

37. Crohn's disease risk alleles on the NOD2 locus have been maintained by natural selection on standing variation.

38. Mineralocorticoid receptor-associated hypertension and its organ damage: clinical relevance for resistant hypertension.

39. Calpain-7 binds to CHMP1B at its second α-helical region and forms a ternary complex with IST1.

40. Expression of aspartyl protease and C3HC4-type RING zinc finger genes are responsive to ascorbic acid in Arabidopsis thaliana.

41. Coactivation of SF-1-mediated transcription of steroidogenic enzymes by Ubc9 and PIAS1.

42. Expression analysis of the VTC2 and VTC5 genes encoding GDP-L-galactose phosphorylase, an enzyme involved in ascorbate biosynthesis, in Arabidopsis thaliana.

43. A non-NadB type L-aspartate dehydrogenase from Ralstonia eutropha strain JMP134: molecular characterization and physiological functions.

44. Determination of walnut protein in processed foods by enzyme-linked immunosorbent assay: interlaboratory study.

45. Adrenocortical zonation in humans under normal and pathological conditions.

46. Soystatin (VAWWMY), a novel bile acid-binding peptide, decreased micellar solubility and inhibited cholesterol absorption in rats.

47. The ALG-2 binding site in Sec31A influences the retention kinetics of Sec31A at the endoplasmic reticulum exit sites as revealed by live-cell time-lapse imaging.

48. Possible role of mitochondrial remodelling on cellular triacylglycerol accumulation.

49. Fast binding kinetics and conserved 3D structure underlie the antagonistic activity of mutant TNF: useful information for designing artificial proteo-antagonists.

50. Prediction of pulmonary function after lung lobectomy by subsegments counting, computed tomography, single photon emission computed tomography and computed tomography: a comparative study.

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