1. Episodic Memory Impairments in Primary Brain Tumor Patients
- Author
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Flavie Bompaire, Damien Ricard, Hervé Taillia, Sabine Hoffmann, Dimitri Psimaras, Daniel Delgadillo, Isabelle Léger, Giulia Berzero, Virginie Jego, Thomas Durand, Marie Baruteau, Durand, T., Berzero, G., Bompaire, F., Hoffmann, S., Leger, I., Jego, V., Baruteau, M., Delgadillo, D., Taillia, H., Psimaras, D., Ricard, D., University of Paris Descartes, University of Pavia, Service de Santé des Armées, PRPHOM, SRBE, LEPID, Institut de Radioprotection et de Sûreté Nucléaire (IRSN), and American Hospital of Paris
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Adult ,Male ,050103 clinical psychology ,medicine.medical_specialty ,Memory, Episodic ,[SDV]Life Sciences [q-bio] ,Brain tumor ,Neuropsychological Tests ,Audiology ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Cognitive assessment ,Memory decay ,Encoding (memory) ,Neurotoxicity ,Humans ,Medicine ,Memory impairment ,0501 psychology and cognitive sciences ,Young adult ,Episodic memory ,Aged ,Retrospective Studies ,Aged, 80 and over ,Cued speech ,Memory Disorders ,Brain Neoplasms ,business.industry ,05 social sciences ,Neuropsychology ,Cognition ,General Medicine ,Middle Aged ,medicine.disease ,3. Good health ,Psychiatry and Mental health ,Clinical Psychology ,Neuropsychology and Physiological Psychology ,Brain neoplasms ,Regression Analysis ,Female ,business ,030217 neurology & neurosurgery - Abstract
International audience; Objective Cognitive investigations in brain tumor patients have mostly explored episodic memory without differentiating between encoding, storage, and retrieval deficits. The aim of this study is to offer insight into the memory sub-processes affected in primary brain tumor patients and propose an appropriate assessment method. Method We retrospectively reviewed the clinical and memory assessments of 158 patients with primary brain tumors who had presented to our departments with cognitive complaints and were investigated using the Free and Cued Selective Reminding Test. Results Retrieval was the process of episodic memory most frequently affected, with deficits in this domain detected in 92% of patients with episodic memory impairments. Storage and encoding deficits were less prevalent, with impairments, respectively, detected in 41% and 23% of memory-impaired patients. The pattern of episodic memory impairment was similar across different tumor histologies and treatment modalities. Conclusion Although all processes of episodic memory were found to be impaired, retrieval was by far the most widely affected function. A thorough assessment of all three components of episodic memory should be part of the regular neuropsychological evaluation in patients with primary brain tumors. © 2018 The Author(s) 2018. Published by Oxford University Press. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.
- Published
- 2017
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