1. Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand.
- Author
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Maude RR, Vatcharapreechasakul T, Ariyaprasert P, Maude RJ, Hongsuwan M, Yuentrakul P, Limmathurotsakul D, Koh GC, Chaowagul W, Day NP, and Peacock SJ
- Subjects
- Abdominal Abscess diagnostic imaging, Abdominal Abscess etiology, Abdominal Pain diagnostic imaging, Abdominal Pain etiology, Adult, Anti-Bacterial Agents administration & dosage, Female, Humans, Liver Diseases diagnostic imaging, Liver Diseases etiology, Male, Melioidosis complications, Melioidosis diagnostic imaging, Middle Aged, Prospective Studies, Splenic Diseases diagnostic imaging, Splenic Diseases etiology, Survival Rate, Thailand epidemiology, Ultrasonography, Abdominal Abscess epidemiology, Abdominal Pain epidemiology, Burkholderia pseudomallei pathogenicity, Liver Diseases epidemiology, Melioidosis epidemiology, Splenic Diseases epidemiology
- Abstract
Retrospective case series from Thailand have reported the presence of intra-abdominal abscesses in around half of patients with melioidosis, a much higher rate than our clinical experience would suggest. We performed a prospective, observational study of 230 adult patients with culture-confirmed melioidosis in which all patients underwent abdominal ultrasound. One or more abscesses were detected in the liver and/or spleen in 77 (33%) cases. These were often multiple (70%, 31/44 in hepatic abscesses and 88%, 50/57 in splenic abscesses) and clinically silent (27% of cases with abscesses presenting with abdominal pain). The mortality rate at 4 weeks post-discharge was lower in patients who were abscess-positive vs abscess-negative (10%, 8/77 vs 20%, 31/153)., (Copyright © 2012 Royal Society of Tropical Medicine and Hygiene. All rights reserved.)
- Published
- 2012
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