1. What is the superior surgical strategy for bi-level cervical spondylosis-anterior cervical disc replacement or anterior cervical decompression and fusion?
- Author
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Xiang-Sheng Tang, Li-Jun Duan, He Zhao, Ding-Yan Zhao, Yongdong Yang, Yu-Shan Gao, Chuan-Hong Li, Yang Xiong, Xing Yu, and Zhen-Guo Hu
- Subjects
030222 orthopedics ,medicine.medical_specialty ,Visual analogue scale ,business.industry ,medicine.medical_treatment ,General Medicine ,Cochrane Library ,medicine.disease ,Surgery ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Patient satisfaction ,medicine.anatomical_structure ,Randomized controlled trial ,law ,Meta-analysis ,Spinal fusion ,medicine ,Cervical spondylosis ,business ,030217 neurology & neurosurgery ,Cervical vertebrae - Abstract
BACKGROUND Nowadays, anterior cervical artificial disc replacement (ACDR) has achieved favorable outcomes in treatment for patients with single-level cervical spondylosis. However, It is still controversial that whether or not it will become a potent therapeutic alternation in treating 2 contiguous levels cervical spondylosis compared with anterior cervical decompression and fusion (ACDF). Therefore, we conducted a systematic review and meta-analysis to compare the efficacy and safety of ACDR and ACDF in patients with 2 contiguous levels cervical spondylosis. METHODS According to the computer-based online search, PubMed, Embase, Web of Science, and Cochrane Library for articles published before July 1, 2017 were searched. The following outcome measures were extracted: neck disability index (NDI), visual analog scale (VAS) neck, VAS arm, Short Form (SF)-12 mental component summary (MCS), SF-12 physical component summary (PCS), overall clinical success (OCS), patient satisfaction (PS), device-related adverse event (DRAE), subsequent surgical intervention (SSI), neurological deterioration (ND), and adjacent segment degeneration (ASD). Methodological quality was evaluated independently by 2 reviewers using the Furlan for randomized controlled trial (RCT) and MINORS scale for clinical controlled trials (CCT). The chi-squared test and Higgin I test were used to evaluate the heterogeneity. A P
- Published
- 2018