6 results on '"Robert Zachariae"'
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2. Experimental manipulations of pain catastrophizing influence pain levels in patients with chronic pain and healthy volunteers
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Robert Zachariae, Helge Kasch, Lene Vase, Peter Svensson, Troels S. Jensen, and Heidi Kjøgx
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Adult ,Male ,Pain Threshold ,medicine.medical_specialty ,Adolescent ,medicine.drug_class ,Severity of Illness Index ,Hypnotic ,Spontaneous pain ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,030202 anesthesiology ,Surveys and Questionnaires ,Adaptation, Psychological ,Healthy volunteers ,Severity of illness ,medicine ,Humans ,In patient ,Young adult ,Pain Measurement ,business.industry ,Catastrophization ,Chronic pain ,Pain Perception ,medicine.disease ,Healthy Volunteers ,Anesthesiology and Pain Medicine ,Neurology ,Physical therapy ,Female ,Pain catastrophizing ,Neurology (clinical) ,Chronic Pain ,business ,030217 neurology & neurosurgery - Abstract
Pain catastrophizing (PC) has been related to pain levels in both patients experiencing acute or chronic pain and in healthy volunteers exposed to experimental pain. Still, it is unclear whether high levels of pain catastrophizing lead to high levels of pain or vice versa. We therefore tested whether levels of pain catastrophizing could be increased and decreased in the same participant through hypnotic suggestions and whether the altered level of situation-specific pain catastrophizing was related to increased and decreased pain levels, respectively. Using the spontaneous pain of 22 patients with chronic tension-type headache and experimentally induced pain in 22 healthy volunteers, participants were tested in 3 randomized sessions where they received 3 types of hypnotic suggestions: Negative (based on the 13 items in the Pain Catastrophizing Scale), Positive (coping-oriented reversion of the Pain Catastrophizing Scale), and Neutral (neutral sentence) hypnotic suggestions. The hypnotic suggestions significantly increased and decreased situation-specific PC in both patients and healthy volunteers (P < 0.001). Also, the levels of pain intensity and pain unpleasantness were significantly altered in both patients and healthy volunteers (P < 0.001). Furthermore, regression analyses showed that changes in pain catastrophizing predicted changes in pain in patients (R = 0.204-0.304; P < 0.045) and in healthy volunteers (R = 0.328-0.252; P < 0.018). This is the first study to successfully manipulate PC in positive and negative directions in both patients with chronic pain and healthy volunteers and to show that these manipulations significantly influence pain levels. These findings may have important theoretical and clinical implications.
- Published
- 2016
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3. Specifying the nonspecific components of acupuncture analgesia
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Lene Vase, Hiroyoshi Yajima, Peter Svensson, Ted J. Kaptchuk, Robert Zachariae, Sara Baram, Søren Schou, Nobuari Takakura, Troels S. Jensen, and Miho Takayama
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Male ,Blinding ,Lidocaine ,Visual analogue scale ,Placebo ,Article ,Double-Blind Method ,Acupuncture ,medicine ,Humans ,Pain Management ,Acupuncture Analgesia ,Anesthetics, Local ,Pain Measurement ,Retrospective Studies ,Analysis of Variance ,Pain, Postoperative ,business.industry ,Acupuncture analgesia ,Tooth, Impacted ,Retrospective cohort study ,Placebo Effect ,Anesthesiology and Pain Medicine ,Neurology ,Anesthesia ,Regression Analysis ,Female ,Neurology (clinical) ,Analysis of variance ,business ,Acupuncture Points ,medicine.drug - Abstract
It is well known that acupuncture has pain-relieving effects, but the contribution of specific and especially non-specific factors to acupuncture analgesia is less clear. One hundred and one patients who developed pain ≥ 3 on a visual analog scale (VAS, 0-10) following third molar surgery were randomized to receive active acupuncture, placebo acupuncture, or no treatment for 30 min with acupuncture needles with potential for double-blinding. Patients’ perception of the treatment (active or placebo), and expected pain levels (VAS) were assessed prior to and halfway through the treatment. Looking at actual treatment allocation, there was no specific effect of active acupuncture (P = 0.240), but a large and significant non-specific effect of placebo acupuncture (P < 0.001), which increased over time. Interestingly, however, looking at perceived treatment allocation, there was a significant effect of acupuncture (P < 0.001) indicating that patients who believed they received active acupuncture had significantly lower pain levels than those who believed they received placebo acupuncture. Expected pain levels accounted for significant and progressively larger amounts of the variance in pain ratings following both active and placebo acupuncture (up to 69.8%), This is the first study to show that under optimized blinding conditions non-specific factors such as patients’ perception of and expectations toward treatment are central to the efficacy of acupuncture analgesia and that these factors may contribute to self-reinforcing effects in acupuncture treatment To obtain an effect of acupuncture in clinical practice it may, therefore, be important to incorporate and optimize these factors.
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- 2013
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4. Effects of an Intervention Aimed at Improving Nurse-Patient Communication in an Oncology Outpatient Clinic
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Robert Zachariae, Mette Trøllund Rask, Jørn Andersen, and Mette Lund Jensen
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Questionnaires ,Adult ,Program evaluation ,Oncology ,medicine.medical_specialty ,Attitude of Health Personnel ,Denmark ,education ,Nursing Staff, Hospital ,Job Satisfaction ,law.invention ,Education, Nursing, Continuing ,Patient satisfaction ,Randomized controlled trial ,law ,Neoplasms ,Surveys and Questionnaires ,Internal medicine ,Ambulatory Care ,medicine ,business.product_line ,Humans ,Outpatient clinic ,Burnout, Professional ,Self-efficacy ,Oncology (nursing) ,business.industry ,Communication ,Oncology Nursing ,Oncologic Nursing ,Training effect ,Communication skills training ,Self Efficacy ,Nursing Education Research ,Mood ,Patient Satisfaction ,Physical therapy ,Female ,Clinical Competence ,Nurse-Patient Relations ,business ,Program Evaluation ,Total Quality Management - Abstract
In an ever more burdened healthcare system, there is an urgent need to investigate whether patients benefit from the resources allocated to nurses' communication skills training in terms of improved patient outcomes. This study aimed to evaluate a standardized two 2-day (33 hours) communication skills training program in nursing cancer care. Twenty-four nurses in an oncology outpatient clinic participated and were randomly assigned to the intervention program or a control group. A total of 413 patients treated in the clinic during 2 recruitment periods (before and after the communication skills training) completed a questionnaire package assessing the nurse-patient relationship, psychological well-being, and cancer-related self-efficacy. Nurse group differences in change scores between time points (baseline, 1 week, and 3 months after the communication skills training) on measures related to communication and work-related stress were all nonsignificant. Time-by-group analyses of patient data showed no training effect on patient perception of nurse empathy and attentiveness, and we found no training effect on patients' anxious/depressed, angry, or positive mood, as well as no effect on cancer-related self-efficacy. The results were unable to support the hypotheses that nurse communication skills training would be associated with improved nurse and patient outcomes.
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- 2009
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5. Personality Traits as Predictors of Quality of Life and Body Image after Breast Reconstruction
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Soren Christensen, Maja O'Connor, Alexander Andersen Juhl, Robert Zachariae, and Tine Engberg Damsgaard
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medicine.medical_specialty ,business.industry ,media_common.quotation_subject ,030230 surgery ,Neuroticism ,03 medical and health sciences ,0302 clinical medicine ,Quality of life ,030220 oncology & carcinogenesis ,Bayesian multivariate linear regression ,Physical therapy ,Medicine ,Personality ,Original Article ,Surgery ,Big Five personality traits ,business ,Prospective cohort study ,Breast reconstruction ,Body mass index ,media_common - Abstract
Background: It has been suggested that personality traits may influence patient-reported outcomes of breast reconstruction, but the research is limited. We investigated, in a prospective study, whether personality traits predict the achieved body image and quality of life (QoL) after breast reconstruction. Methods: Patients planning to undergo breast reconstruction at a University Hospital were consecutively recruited from January 2014 to January 2016. Participants completed validated measures of personality, body image, and QoL, before and 6 months after breast reconstruction. The influence of personality traits on achieved body image and QoL was explored with multivariate linear regression modelling, adjusting for baseline scores, demographics, and clinical variables. Results: Of 247 eligible patients, 208 (84%) participated. Twelve patients (6%) were excluded due to failed reconstruction. Of the remaining 196 patients, 180 (92%) completed the follow-up questionnaire. When adjusted for baseline QoL scores, higher trait Neuroticism, higher trait Openness, and higher body mass index measured at baseline showed to be independent and statistically significant predictors of deteriorating QoL scores from baseline to 6-month follow-up (P < 0.001; R2 = 0.45). When adjusted for body image scores at baseline, higher trait Neuroticism and immediate reconstruction were found to be independent predictors of poorer body image from baseline to 6-months follow-up (P < 0.001; R2 = 0.36). Conclusions: The present study suggests personality traits, in particular Neuroticism, as independent predictors of the achieved body image and QoL after breast reconstruction. Weighing in the personality traits of the patients may be an important adjunct in improving patient-reported outcomes after breast reconstructions.
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- 2017
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6. Self-Hypnosis for Coping With Labor Pain
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Ellen A. Nohr, Niels Uldbjerg, G. Rosen, Robert Zachariae, and Anette Werner
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Coping (psychology) ,medicine.medical_specialty ,Randomized controlled trial ,business.industry ,law ,Self-hypnosis ,Physical therapy ,Medicine ,Labor pain ,business ,law.invention - Published
- 2014
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