1. External Validation of the Timed Up and Go Test as Measure of Objective Functional Impairment in Patients With Lumbar Degenerative Disc Disease
- Author
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Michal Ziga, Astrid Weyerbrock, Nicolai Maldaner, Oliver Bozinov, Martin N. Stienen, Oliver Gautschi, Marketa Sosnova, Anna M Zeitlberger, and University of Zurich
- Subjects
Adult ,Male ,medicine.medical_specialty ,Spinal stenosis ,610 Medicine & health ,Neurogenic claudication ,Intervertebral Disc Degeneration ,Timed Up and Go test ,Severity of Illness Index ,Degenerative disc disease ,10180 Clinic for Neurosurgery ,03 medical and health sciences ,0302 clinical medicine ,Lumbar ,Outcome Assessment, Health Care ,Back pain ,medicine ,Humans ,Patient Reported Outcome Measures ,Prospective Studies ,030212 general & internal medicine ,Aged ,Pain Measurement ,Lumbar Vertebrae ,business.industry ,Lumbar spinal stenosis ,Middle Aged ,medicine.disease ,Time and Motion Studies ,Physical therapy ,Female ,Surgery ,Neurology (clinical) ,medicine.symptom ,business ,human activities ,030217 neurology & neurosurgery ,Lumbar disc disease - Abstract
BACKGROUND The Timed Up and Go (TUG) test is the most commonly applied objective measure of functional impairment in patients with lumbar degenerative disc disease (DDD). OBJECTIVE To demonstrate external content validity of the TUG test. METHODS Consecutive adult patients, scheduled for elective lumbar spine surgery, were screened for enrollment into a prospective observational study. Disease severity was estimated by patient-reported outcome measures (PROMs; Visual Analog Scales [VAS], Core Outcome Measures Index [COMI] back, Zurich Claudication Questionnaire [ZCQ]) and the TUG test. Pearson correlation coefficients (PCCs) were used to describe the relationship between logarithmic TUG test raw values and PROMs. RESULTS A total of 70 patients (mean age 55.9 ± 15.4 yr; 38.6% female; 27.1% previous spine surgery; 28.6% lower extremity motor deficits) with lumbar disc herniation (50%), lumbar spinal stenosis (34.3%), or instability requiring spinal fusion (15.7%) were included. The mean TUG test time was 10.8 ± 4.4 s; age- and sex-adjusted objective functional impairment (OFI) T-score was 134.2 ± 36.9. A total of 12 (17.1%) patients had mild, 14 (20%) moderate, and 9 (12.9%) severe OFI, while 35 (50%) had TUG test results within the normal population range (no OFI). PCCs between TUG test time and VAS back pain were r = 0.37 (P = .002), VAS leg pain r = 0.37 (P = .002), COMI back r = 0.50 (P
- Published
- 2020
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