1. Age-adapted Variation in Screening Interval of Fecal Immunochemical Test May Improve its Participation and Colonoscopy Acceptance
- Author
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Joung Il Lee, Jung Won Jeon, Jin Young Yoon, Kwang Ro Joo, Hyun Phil Shin, Min Seob Kwak, and Jae Myung Cha
- Subjects
Male ,medicine.medical_specialty ,Time Factors ,Seoul ,Colorectal cancer ,Colonoscopy ,Gastroenterology ,Feces ,03 medical and health sciences ,0302 clinical medicine ,Predictive Value of Tests ,Internal medicine ,Biomarkers, Tumor ,Odds Ratio ,medicine ,Humans ,Early Detection of Cancer ,Aged ,Retrospective Studies ,Chi-Square Distribution ,medicine.diagnostic_test ,business.industry ,Age Factors ,Retrospective cohort study ,Odds ratio ,Middle Aged ,Patient Acceptance of Health Care ,medicine.disease ,Immunohistochemistry ,Confidence interval ,Annual Screening ,Logistic Models ,030220 oncology & carcinogenesis ,Predictive value of tests ,Female ,030211 gastroenterology & hepatology ,Colorectal Neoplasms ,business ,Chi-squared distribution ,Program Evaluation ,Demography - Abstract
GOALS We determined appropriate intervals for administering the fecal immunochemical test (FIT) and performance outcomes in an Asian national colorectal cancer (CRC) screening program. BACKGROUND The optimal interval for FIT in CRC screening is unclear, especially in Asian populations. STUDY Between January 2009 and December 2015, 13,480 individuals aged 50 years or older with an initial negative FIT result underwent 2 rounds of FIT screening at intervals of 1 (annual group, 5333), 2 (biennial group, 7363), or 3 years (triennial group, 784). Positive rates of FIT, colonoscopy acceptance, colonoscopy findings, and detection rates for CRC and advanced neoplasia were compared according to FIT intervals. RESULTS The overall positivity rate of FIT in the second screening round was significantly higher in men and in older subjects than in the entire sample. Younger subjects were less likely to undergo annual FIT (36.0% vs. 46.4%, P
- Published
- 2017