19 results on '"John W. Siebert"'
Search Results
2. Discussion: Soft-Tissue Reconstruction in Progressive Hemifacial Atrophy: Current Evidence and Future Directions
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Sarah M. Lyon and John W. Siebert
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Surgery - Published
- 2022
3. 3. Making Headway in Surgical Education at Home and Abroad: Use of an Inexpensive Novel 3-D Learning Model for Plastic Surgery Education
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Ellen C. Shaffrey, Ava G. Grotting, Brett F. Michelotti, John W. Siebert, Jeffrey D. Larson, and Michael L. Bentz
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Surgery - Published
- 2022
4. A 26-Year Experience with Microsurgical Reconstruction of Hemifacial Atrophy and Linear Scleroderma
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Jenny T. Chen, John W. Siebert, Jacqueline S. Israel, and Daniel B. Schmid
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Adult ,Microsurgery ,medicine.medical_specialty ,Adolescent ,Esthetics ,Treatment outcome ,Free Tissue Flaps ,Scleroderma ,Scleroderma, Localized ,Young Adult ,030207 dermatology & venereal diseases ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Atrophy ,Facial Hemiatrophy ,Preoperative Care ,medicine ,Humans ,Linear Scleroderma ,Child ,Aged ,business.industry ,Gold standard ,Skin Transplantation ,Middle Aged ,medicine.disease ,Dermatology ,Lip ,Hemifacial atrophy ,stomatognathic diseases ,Burning out ,Treatment Outcome ,Facial Asymmetry ,Child, Preschool ,Female ,Surgery ,business ,Parry-romberg disease ,030217 neurology & neurosurgery - Abstract
Parry Romberg disease (hemifacial atrophy) and linear scleroderma (coup de sabre) are progressive, usually unilateral facial atrophies of unknown cause. The gold standard treatment for these patients has been microsurgical reconstruction following the "burning out" of the facial atrophy and stable contour for 2 years.The authors report their experience treating patients with hemifacial atrophy and linear scleroderma with free tissue transfers between 1989 and 2016. A modified parascapular flap based on the circumflex scapular artery was most commonly used.A total of 177 patients were included. The most common complication was hematoma, occurring in 12 patients (7 percent). Follow-up ranged from 1 to 26 years. All patients subjectively experienced improved facial symmetry and aesthetics. No disease process has recurred to date, even in cases of severe, progressive disease.In the authors' experience, patients treated early in their disease course have immediate and sustained correction of their deformity, with slowing or in most cases cessation of the disease process following free tissue transfer. The authors now advocate for immediate reconstruction for active disease, especially in young children.Therapeutic, IV.
- Published
- 2018
5. Abstract 181
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John W. Siebert, Rebecca L Farmer, Samuel O. Poore, Sandra Splinter BonDurant, Sarah M. Lyon, Jacqueline S. Israel, Katherine M. Gast, and Kirsten A. Gunderson
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medicine.medical_specialty ,business.industry ,medicine ,Surgery ,Medical physics ,business - Published
- 2020
6. Challenging Traditional Thinking
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Jenny T. Chen, Daniel B. Schmid, and John W. Siebert
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Surgery - Published
- 2014
7. Achieving Aesthetic Results in Facial Reconstructive Microsurgery
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Pierre B. Saadeh, John W. Siebert, and Nicholas T. Haddock
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Adult ,Blepharoplasty ,Male ,Reoperation ,Microsurgery ,medicine.medical_specialty ,Adolescent ,Esthetics ,Adipose Tissue, White ,Treatment outcome ,Free Tissue Flaps ,Young Adult ,Lipectomy ,Reconstructive microsurgery ,Humans ,Medicine ,Medical physics ,Facial Injuries ,business.industry ,Plastic Surgery Procedures ,Rhinoplasty ,Tissue transfer ,Surgery ,Treatment Outcome ,Face surgery ,Patient Satisfaction ,Face ,Rhytidoplasty ,Female ,business - Abstract
Free tissue transfer to improve bulk and contour in facial deformities has been proven useful, yet refinements that turn an acceptable result into an excellent result are essential to reconstruction. The authors reviewed their experience and described these refinements.The charts of 371 free tissue transfer cases (1989 to 2010) performed by the senior author (J.W.S.) were reviewed. Free tissue transfer of a circumflex scapular variant flap or superficial inferior epigastric was performed to treat deformities arising from hemifacial atrophy (n = 126), hemifacial microsomia (n = 89), radiation therapy (n = 40), bilateral malformations including lupus and polymyositis (n = 50), other congenital anomalies (n = 25), facial palsy (n = 17), and burns and trauma (n = 24).Revision surgery planning began at initial flap operation where the flap was stretched maximally and interdigitated with recipient tissue. More tissue was required in the malar region. Revision refinement was indicated in all cases (after 6 months). Flap revision involved liposuction, debulking, reelevation, and release of tethering, followed by tissue rearrangement by means of advancement, rotation, transposition, and/or turnover flaps of subcutaneous tissues from the previous free flap. The jawline frequently required more debulking. Periorbital reconstruction was combined with lower lid support with or without canthal repositioning. Conventional face-lift techniques with the flap as superficial musculoaponeurotic system augmented the result. Autologous fat injection to the alar rim, medial canthus, upper eyelid, and lip was a useful adjunct. Severe lip deficiencies were addressed with local flaps.The keys to improving results were continual critical reassessment, open-mindedness to new approaches, and maintaining high expectations.Therapeutic, V.
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- 2012
8. Microvascular Reconstruction of the Pediatric Mandible
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Michael T. Longaker, Stephen M. Warren, Lawrence E. Brecht, Loren J. Borud, and John W. Siebert
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Male ,Microsurgery ,medicine.medical_specialty ,Adolescent ,Mandible ,Surgical Flaps ,Condyle ,stomatognathic system ,Occlusion ,medicine ,Humans ,Mandibular Diseases ,Fibula ,Child ,Retrospective Studies ,business.industry ,Microcirculation ,Fibrous dysplasia ,Soft tissue ,Plastic Surgery Procedures ,medicine.disease ,Hypoplasia ,Surgery ,Hemifacial microsomia ,stomatognathic diseases ,Female ,business - Abstract
Background: Free tissue transfer for adult mandibular reconstruction is a well-established technique; however, there are few reports of pediatric microvascular lower jaw reconstruction. Methods: This retrospective study was undertaken to review the range of indications, choices, safety, and efficacy of pediatric free tissue transfer to the lower jaw. All patients underwent a parascapular, scapular, or fibula free tissue transfer. Flap choice was based on preoperative clinical examination, radiographic findings, need for linear or multiplanar mandibular reconstruction, need for dental restoration, severity of soft-tissue deficit, and peroneal artery anatomy. Results: Over a 10-year period (1989 to 1999), we performed eightfree tissue transfers to reconstruct the mandibles of seven children, aged 6 to 17 years. Indications included radiation-induced hypoplasia (n = 1), postsurgical resection of fibrous dysplasia (n = 1), hemifacial microsomia (n = 3), Robin sequence with severe micrognathia (n = 1), and osteomyelitis (n = 1). The authors transferred four parascapular osseocutaneous, two scapular osseocutaneous, one fibular osseocutaneous, and one fibular osseous flap to reconstruct five ramus, four condyle, and two subtotal mandibular defects. All bony defects were successfully bridged and all osseous flaps successfully integrated. Postoperatively, mandibular symmetry and Angle class I occlusion were restored in all patients throughout the 10.5-year follow-up period (range, 9 to 14 years). Two patients received osseointegrated dental implants. Our only complication was the partial loss of a skin paddle. Conclusion: Microvascular reconstruction of the pediatric mandible, in selected patients, is a safe, reliable procedure that provides the bone stock and soft tissue necessary to restore normal maxillomandibular growth and dental rehabilitation.
- Published
- 2007
9. Salvage of Silicone-Treated Facial Deformities Using Autogenous Free Tissue Transfer
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Sheel Sharma, John W. Siebert, and Ernest S. Chiu
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Adult ,Male ,Reoperation ,Microsurgery ,medicine.medical_specialty ,Time Factors ,Fistula ,Silicones ,Free flap ,Surgical Flaps ,chemistry.chemical_compound ,Hematoma ,Silicone ,Facial Hemiatrophy ,Dyschromia ,medicine ,Humans ,Inframammary fold ,Retrospective Studies ,Salvage Therapy ,Dysesthesia ,business.industry ,Suture Techniques ,Soft tissue ,Middle Aged ,Plastic Surgery Procedures ,medicine.disease ,Surgery ,Adipose Tissue ,chemistry ,Female ,medicine.symptom ,business ,Algorithms - Abstract
Background: Silicone, in the form of injectable liquid and prosthetic blocks, has been used to correct facial contour defects. However, silicone also has been associated with many complications including malposition, dyschromia, dysesthesia, contractures, infection, and fistula. Complications related to injectable-liquid and prosthetic-block silicone use in treatment of facial deformities pose a challenging surgical dilemma. Methods: Over a 15-year period, microvascular free flap technique has been used successfully as a surgical tool to correct severe soft-tissue complications of the face resulting from silicone treatment of facial contour deformities. Surgical treatment guidelines, methods, and results for treating this difficult problem with free tissue transfer are presented. Results: In 23 patients, 24 free tissue transfers (22 inframammary extended circumflex scapular free flaps and two superficial inferior epigastric free flaps) were performed. Flap survival was 100 percent. Both hematoma and skin necrosis were encountered in three of 24 cases (12.5 percent). Revisional surgery combined with aesthetic surgical procedures was required in 20 of 24 cases (83 percent). Conclusions: We recommend the following surgical treatment guidelines for this unique subset of patients: silicone excision with immediate microvascular free flap reconstructive procedure when the skin and soft tissue are mildly to moderately affected, or silicone excision with delayed reconstructive procedure when the skin and soft tissue are severely affected. Free tissue transfer is a useful surgical tool for salvaging severe facial skin and soft-tissue deformities caused by previous silicone treatment.
- Published
- 2005
10. Facial Flap Contouring Using a Sinus Microdebrider
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John W. Siebert, Jacqueline S. Israel, Thomas J. Sitzman, Samuel O. Poore, and Ashish Y. Mahajan
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medicine.medical_specialty ,Contouring ,business.industry ,Plastic Surgery Procedures ,Surgical Flaps ,Surgery ,medicine.anatomical_structure ,Debridement ,Face ,medicine ,Humans ,business ,Sinus (anatomy) - Published
- 2013
11. Abstract 17. Congenital Blepharoptosis Dynamic Reconstruction
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John W. Siebert, John Noon, Samuel O. Poore, Amanda Nelson, Gustavo Herdocia Baus, Ruston Sanchez, and Michael L. Bentz
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Nursing ,business.industry ,Global health ,Medicine ,Surgery ,Narrative ,AAPS 2017 Abstract Supplement ,business ,Congenital Blepharoptosis - Published
- 2017
12. Delayed in Utero Repair of Surgically Created Fetal Cleft Lip and Palate
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Harrison Mr, John W. Siebert, Michael T. Longaker, Henry E. Rice, William Y. Hoffman, Hedrick Mh, N S Adzick, and Vander Wall Kj
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medicine.medical_specialty ,Time Factors ,Cleft Lip ,medicine.medical_treatment ,Third trimester ,Facial Bones ,Cicatrix ,Fetus ,Animal model ,Pregnancy ,Animals ,Medicine ,Hysterotomy ,Wound Healing ,Sheep ,business.industry ,Anatomy ,Surgery ,Cleft Palate ,Disease Models, Animal ,In utero ,Incomplete regeneration ,Fetal lamb ,Female ,business ,Large animal - Abstract
To properly evaluate the potential benefits of in utero repair for cleft lip and palate, an animal model of cleft lip and palate formation is needed that simulates human cleft morphology. We have developed a fetal lamb model in which incisional or excisional unilateral cleft lips were created early in gestation and later repaired. Through a maternal celiotomy and hysterotomy, six excisional and six incisional clefts were created in early first trimester fetal lambs. Clefts were created by a novel space helmet technique and made completely through the lip and the alveolus. Two weeks later, the wound edges were freshened and repaired in all but one lamb in each group. In the early third trimester, the fetuses were harvested and studied. We found that the incisional clefts healed spontaneously with replacement of the native reticular collagen pattern and with regeneration of the skin appendages. However, the excisional clefts did not autorepair and, when repaired surgically, healed without a collagen scar but showed no regeneration of the skin appendages. This preliminary study is the first successful large animal model where cleft lips and palates were created, allowed to develop with the cleft, and later repaired in utero. Prior to repair, the edges of the excisional clefts epithelialize. When repaired early in the third trimester, excisional clefts heal without a dermal scar but exhibit incomplete regeneration of the skin appendages.
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- 1996
13. Scar Formation: The Spectral Nature of Fetal and Adult Wound Repair
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Mark W. J. Ferguson, David J. Whitby, John W. Siebert, Michael T. Longaker, Mamta Shah, and James R. Armstrong
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Adult ,Wound Healing ,medicine.medical_specialty ,Pathology ,Fetus ,business.industry ,Gestational Age ,Surgery ,Cicatrix ,Species Specificity ,Suture (anatomy) ,Organ Specificity ,Animals ,Humans ,Medicine ,Wound healing ,business - Published
- 1996
14. Microsurgical Correction of Facial Asymmetry in 60 Consecutive Cases
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Goesel Anson, John W. Siebert, and Michael T. Longaker
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Adult ,Male ,Microsurgery ,medicine.medical_specialty ,Adolescent ,medicine.medical_treatment ,Postoperative hematoma ,Free flap ,Surgical Flaps ,Postoperative Complications ,medicine.artery ,Humans ,Medicine ,Craniofacial ,Child ,Aged ,business.industry ,Middle Aged ,medicine.disease ,Superficial temporal artery ,Surgery ,Hemifacial microsomia ,Plastic surgery ,Facial Asymmetry ,Female ,business ,Facial symmetry - Abstract
Restoring soft-tissue contour in patients with facial asymmetry is a difficult problem for plastic surgeons. We report our experience with 57 consecutive patients who underwent 60 microvascular free flaps for the correction of facial asymmetry between July of 1989 and June of 1994. Etiologies of facial asymmetry included hemifacial microsomia, hemifacial atrophy, postradiation sequelae, burns and trauma, and selected congenital anomalies. Thirty-eight patients were reconstructed with a customized parascapular flap incorporating extensions of dorsal thoracic fascia. Other donor sites utilized were as follows: six superficial inferior epigastric flaps, three myocutaneous flaps, seven muscle flaps, and six fasciocutaneous flaps with bone. To correct facial asymmetry, the recipient site was dissected through a limited preauricular incision whenever feasible, and the superficial temporal artery and vein were used as recipient vessels. A monitoring skin paddle was rarely used. There were no flap losses in this series. Six patients experienced a postoperative hematoma, three of which were drained at the bedside. Limited skin slough occurred in three patients. No donor-site complications other than hypertrophic scarring were encountered. Flap revisions were performed in 22 of the 57 patients to maximize aesthetic results. Based on our experience, we feel that the operative approach presented here allows excellent and stable correction of facial asymmetry due to a variety of etiologies. Furthermore, this technique is applicable to other congenital craniofacial deformities such as Treacher-Collins syndrome and orbital-facial clefts.
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- 1996
15. Transient Postoperative Stenosis in Small-Vessel Anastomoses
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Barry J. Kanner, John W. Siebert, Martin J. Moskovitz, David A. Baron, Robert E. Tuchler, and Ling Zhang
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Male ,Microsurgery ,medicine.medical_specialty ,Vasodilator Agents ,Constriction, Pathologic ,Femoral artery ,Anastomosis ,Constriction ,Rats, Sprague-Dawley ,Surgical anastomosis ,Postoperative Complications ,Suture (anatomy) ,medicine.artery ,medicine ,Animals ,Papaverine ,business.industry ,Anastomosis, Surgical ,Suture Techniques ,medicine.disease ,Rats ,Surgery ,Femoral Artery ,Stenosis ,Ultrasonography, Doppler, Pulsed ,Microangiography ,Anesthesia ,Microscopy, Electron, Scanning ,business ,Blood Flow Velocity ,Platelet Aggregation Inhibitors ,medicine.drug - Abstract
Using a newly developed Doppler probe, we have found that a standard suture anastomosis in a rat femoral artery is accompanied by significant (30-60%) cross-sectional area stenosis, which dissipates to baseline levels within 24 hours. We hypothesized that spasm, deposition of coagulation products, or the suture technique itself was responsible. Topical vasodilators (papaverine, sodium nitroprusside, lidocaine) and intravenous thromboxane A2 synthetase inhibitor and receptor blocking agent (Ridogrel, 4 mg/ml), anticoagulants heparin and SC4992 (an experimental platelet inhibitor/arginine-glycine-aspartic acid analogue), were administered. No drug had any significant effect on preventing postoperative stenosis. Varied suture bites affected stenosis measurements. Scanning electron microscopy and light microscopy displayed "bunching" of vessel wall in the suture ties. This was confirmed with methyl methacrylate corrosion casts and microangiography. "Sham" anastomoses also produced stenosis, which was relieved when sutures were removed. We conclude that suture anastomosis of small vessels is accompanied by significant cross-sectional stenosis caused by the physical action of tensioned sutures. This effect dissipates over a 24-hour postoperative period. The mechanism behind these changes and the clinical importance of this effect are still under investigation.
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- 1995
16. Fetal Fibroblast Contraction of Collagen Matrices In Vitro
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John W. Siebert, Patrice Gregory, Michael R. Harrison, Sandra J. Piscatelli, Michael T. Longaker, Basil M. Michaels, and Russell W. Jennings
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medicine.medical_specialty ,Contraction (grammar) ,Gestational Age ,In Vitro Techniques ,Cicatrix ,Fetus ,Pregnancy ,Transforming Growth Factor beta ,Collagen matrices ,Epidermal growth factor ,Internal medicine ,medicine ,Animals ,Fibroblast ,Skin ,Wound Healing ,Sheep ,Epidermal Growth Factor ,integumentary system ,business.industry ,Fibroblasts ,In vitro ,medicine.anatomical_structure ,Endocrinology ,Prenatal Injuries ,Polyvinyl Alcohol ,Female ,Surgery ,Collagen ,Contracture ,medicine.symptom ,business ,Transforming growth factor - Abstract
Wound contraction is an important component of healing but, in the extreme, may lead to excessive scar formation and pathological wound contracture. Fetal rabbit wounds heal without contraction or scarring, whereas excisional fetal sheep wounds have been shown to contract, but no scarring or pathological wound contracture is noted. We used an in vitro model, the fibroblast-populated collagen lattice, to study the ability of fetal fibroblasts to coordinate contraction of a collagen matrix and the modulating effects of epidermal growth factor and transforming growth factor-beta 1 on this contraction. With increasing gestational age, fibroblasts increased the degree of collagen lattice contraction. Epidermal growth factor inhibited contraction by fetal fibroblasts, whereas transforming growth factor-beta 1 stimulated it. These findings suggest that while intrinsic differences between fetal and adult fibroblasts exist, polypeptide growth factors may operate at the site of tissue repair to alter cell phenotype. Further work is underway to delineate the role of soluble protein factors responsible for the absence of scarring and contracture seen in the fetal wound.
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- 1994
17. Fetal Wound Healing
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Andrew Burd, H P Ehrlich, John W. Siebert, J Weinzweig, and J G McCarthy
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Pathology ,medicine.medical_specialty ,Fetus ,business.industry ,Lumen (anatomy) ,Human skin ,Hydroxyproline ,chemistry.chemical_compound ,Hydroxylysine ,medicine.anatomical_structure ,chemistry ,Hyaluronic acid ,medicine ,Surgery ,Wound healing ,business ,Subcutaneous tissue - Abstract
Human fetal surgery is being successfully performed today in a small number of highly selected patients for conditions that may lead to irreversible damage to the fetus and threaten the viability of the newborn. Following surgical repair, fetal wounds heal without scarring. This study was initiated to characterize fetal wounds both histologically and biochemically. Gore-Tex tubing was implanted into the subcutaneous tissue of the back of fetal, newborn, and adult New Zealand white rabbits. Light microscopic examination of healed wounds revealed no evidence of scar formation. Electron microscopy demonstrated a striated fibrillar structure suggestive of collagen within the lumen of the Gore-Tex tubing implants. Amino acid analysis (sensitivity 40 pmol) confirmed the presence of hydroxylysine and hydroxyproline within the Gore-Tex wound chambers indicating the presence of collagen in fetal wounds. The small amount of collagen precluded the typing of the collagen using cyanogen bromide peptide analysis. The absence of scarring and the small amounts of detectable collagen suggest a high degree of reorganization of the connective tissues involved in repair. The fetal wound matrix is rich in hyaluronic acid. Topical hyaluronic acid has been associated experimentally with a reduced amount of scarring in postnatal wound healing. Hyaluronic acid extracted from human skin and scar tissue is associated with collagen and other proteins. We propose that a hyaluronic acid-collagen-protein complex may play a role in fetal wound healing.
- Published
- 1990
18. Fetal Wound Healing
- Author
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John W. Siebert, D. Andrew R. Burd, Joseph G. McCarthy, Jeffrey Weinzweig, and H. Paul Ehrlich
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Surgery - Published
- 1990
19. Fasciocutaneous Flaps
- Author
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Geoffrey G. Hallock and John W. Siebert
- Subjects
Surgery - Published
- 1994
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