Author: "Japour A" / Publisher: ovid technologies (wolters kluwer health) - Searchworks@Jio Institute Digital Library Search Results

14 results on '"Japour A"'

1. Icosapent Ethyl Reduces Ischemic Events in Patients With a History of Previous Coronary Artery Bypass Grafting: REDUCE-IT CABG

Author: Subodh Verma, Deepak L. Bhatt, Ph. Gabriel Steg, Michael Miller, Eliot A. Brinton, Terry A. Jacobson, Nitish K. Dhingra, Steven B. Ketchum, Rebecca A. Juliano, Lixia Jiao, Ralph T. Doyle, Craig Granowitz, C. Michael Gibson, Duane Pinto, Robert P. Giugliano, Matthew J. Budoff, R. Preston Mason, Jean-Claude Tardif, Christie M. Ballantyne, Fabrice M.A.C. Martens, Astrid Schut, Brian Olshansky, Mina Chung, Al Hallstrom, Lesly Pearce, Cyrus Mehta, Rajat Mukherjee, Anjan K. Chakrabarti, Eli V. Gelfand, Megan Carroll Leary, Duane S. Pinto, Yuri B. Pride, Steven Ketchum, Ramakrishna Bhavanthula, Gertrude Chester, Christina Copland, Katelyn Diffin, Ralph Doyle, Kurt Erz, Alex Giaquinto, Paula Glanton, Angela Granger, Richard H. Iroudayassamy, Rebecca Juliano, James Jin, Dimitry Klevak, Hardik Panchal, Robert Wang, Shin-Ru Wang, Gerard Abate, Peggy J. Berry, Rene Braeckman, Declan Doogan, Anne Elson, Amy HauptmannBaker, Isabel Lamela, Catherine Lubeck, Mehar Manku, Sabina Murphy, Monica Sanford, William Stirtan, Paresh Soni, Arnaud Bastien, Demetria Foster, Evangelito Gascon, Judith Johnson, Lasbert Latona, Gang Liu, Sandra Palleja, Nelly Sanjuan, Jimmy Shi, William Stager, Mukund Venkatakrishnan, Ahmed Youssef-Agha, Julie Zhu, Leela Aertker, Suresh Ankolekar, Lisa Goldberg, Natasa Rajicic, Jianfen Shu, Heng Zou, Magdy Mikhail, Gamil Dawood, N. Mathew Koshy, Sandip K. Mukherjee, Rafik Abadier, Andrea L. Lawless, William P. McGuinn, Howard Weintraub, Kathryn Rohr, Edmund Claxton, Robert J. Weiss, Terry D. Klein, Mani Nallasivan, Stephen Crowley, Marilyn King, Anthony D. Alfieri, David Fitz-Patrick, Irving Loh, Nolan J. Mayer, Rakesh Prashad, Samuel Lederman, Debra Weinstein, Harold E. Bays, Keith Chu, Alireza Maghsoudi, Paul D. Thompson, Jeff Carstens, Anna Chang, Kenneth R. Cohen, Julius Dean, Howard S. Ellison, Bernard Erickson, Enrique A. Flores, Daniel W. Gottlieb, Paul Grena, John R. Guyton, Peter H. Jones, John M. Joseph, Norman E. Lepor, Sam Lerman, Robert D. Matheney, Theodore R. Pacheco, Michael B. Russo, John Rubino, Edward S. Pereira, Albert A. Seals, Eduardo Viera, Alan D. Steljes, Jason Thompson, Shaival Kapadia, Michael McIvor, Jorge E. Salazar, Jose O. Santiago, Ralph Vicari, Martin R. Berk, William A. Kaye, Marcus McKenzie, David Podlecki, Brian D. Snyder, Stephen Nash, David M. Herrington, Wallace Johnson, Joseph R. Lee, Ronald Blonder, Alpa M. Patel, Ramon Castello, Susan Greco, Dean J. Kereiakes, Venkatesh K. Nadar, Mark Nathan, Ranganatha P. Potu, Robert Sangrigoli, Richard Smalling, Mitchell Davis, Robert Braastad, James McCriskin, Kunal Bodiwala, Joe L. Hargrove, Mark W. Graves, George Emlein, Raegan W. Durant, James W. Clower, Rohit Arora, Narendra Singh, Lisa Warsinger Martin, W Herbert Haught, Marc P. Litt, Michael D. Klein, Peter Hoagland, Michael Goldstein, Marco S. Mazzella, Daniel H. Dunker, Brian H. Kahn, Carlos S. Ince, Frank A. McGrew, Jay Lee, David Pan, Salman A. Khan, Uri Elkayam, Wasim Deeb, Anne C. Goldberg, Christopher S. Brown, Wayne N. Leimbach, Thomas S. Backer, David R. Sutton, Joel Gellman, Anu R. George, Alan S. Hoffman, Mark Kates, Kishlay Anand, Robert Bear, Brendan J. Cavanaugh, Ramon G. Reyes, Rodolfo Sotolongo, Kenneth Sabatino, Kevin Gallagher, Ehab Sorial, Chris Geohas, Kathleen E. Magness, Bernard P. Grunstra, Frederik A. Martin, William S. Knapp, Mel E. Lucas, John J. Champlin, Jason Demattia, Patrick H. Peters, Judith Kirstein, William J. Randall, Cezar S. Staniloae, Jennifer G. Robinson, Alexander Adler, Christopher Case, Andrew J. Kaplan, Gregory F. Lakin, Krishan K. Goyle, Michael J. DiGiovanna, Chester L. Fisher, Michael Lillestol, Michael Robinson, Robert G. Perry, Lawrence S. Levinson, Brian G. Everhart, Robert D. Madder, Earl F. Martin, Earl E. Martin, Imtiaz Alam, Jose Mari L. Elacion, Robina Poonawala, Taddese T. Desta, Jerome A. Robinson, Gilbert J. Martinez, Jakkidi S. Reddy, Jeffrey D. Wayne, Samuel Mujica Trenche, Westbrook I. Kaplan, Rubin H. Saavedra, Michael D. DiGregorio, Barry D. Bertolet, Neil J. Fraser, Terence T. Hart, Ronald J. Graf, David A. Jasper, Michael Dunn, Dan A. Streja, David J. Strobl, Nan Jiang, Vicki Kalen, Richard Mascolo, Mercedes B. Samson, Michael Stephens, Bret M. Bellard, Mario Juarez, Patrick J. McCarthy, John B. Checton, Michael Stillabower, Edward Goldenberg, Amin H. Karim, Naseem Jaffrani, Robert C. Touchon, Erich R. Fruehling, Clayton J. Friesen, Pradipta Chaudhuri, Frank H. Morris, Robert E. Broker, Rajesh J. Patel, Susan Hole, Randall P. Miller, Francisco G. Miranda, Sadia Dar, Shawn N. Gentry, Paul Hermany, Charles B. Treasure, Miguel E. Trevino, Raimundo Acosta, Anthony Japour, Samuel J. Durr, Thomas Wang, Om P. Ganda, Perry Krichmar, James L. Arter, Douglas Jacoby, Michael A. Schwartz, Amer Al-Karadsheh, Nelson E. Gencheff, John A. Pasquini, Richard Dunbar, Sarah Kohnstamm, Hector F. Lozano, Francine K. Welty, Thomas L. Pitts, Brian Zehnder, Salah El Hafi, Mark A. King, Arnold Ghitis, Marwan M. Bahu, Hooman Ranjbaran Jahromi, Ronald P. Caputo, Robert S. Busch, Michael D. Shapiro, Suhail Zavaro, Munib Daudjee, Shahram Jacobs, Vipul B. Shah, Frank Rubalcava, Mohsin T. Alhaddad, Henry Lui, Raj T. Rajan, Fadi E. Saba, Mahendra Pai N Gunapooti, Tshiswaka B. Kayembe, Timothy Jennings, Robert A. Strzinek, Michael H. Shanik, Pradeep K. Singh, Alastair C. Kennedy, Howard Rubenstein, Ramin Manshadi, Joanne Ladner, Lily Kakish, Ashley Kakish, Amy L. Little, Jaime Gerber, Nancy J. Hinchion, Janet Guarino, Denise Raychok, Susan Budzinski, Kathleen Kelley-Garvin, April Beckord, Jessica Schlinder, Arthur Schwartzbard, Stanley Cobos, Deborah Freeman, David Abisalih, Dervilla McCann, Kylie Guy, Jennifer Chase, Stacey Samuelson, Madeline Cassidy, Marissa Tardif, Jaime Smith, Brenna Sprout, Nanette Riedeman, Julie Goza, Lori Johnson, Chad Kraske, Sheila Hastings, Chris Dutka, Stephanie Smith, Toni McCabe, Kathleen Maloney, Paul Alfieri, Vinay Hosemane, Chanhsamone Syravanh, Cindy Pau, April Limcoiloc, Tabitha Carreira, Taryn S. Kurosawa, Razmig Krumian, Krista Preston, Ashraf Nashed, Daria Schneidman-Fernandez, Jack Patterson, John Tsakonas, Jennifer Esaki, Lynn Sprafka, Porous Patel, Brian Mitchell, Erin M. Ross, Donna Miller, Akash Prashad, Kristina M. Feyler, Natasha Juarbe, Sandra Herrera, Sarah M. Keiran, Becky Whitehead, Whitney Asher, Coury Hobbs, Abbey Elie, Jean Brooks, Amanda L. Zaleski, Brenda Foxen, Barb Lapke, Philippa Wright, Bristol Pavol, Gwen Carangi, Marla Turner, Katharine W. Sanders, Rikita S. Delamar, Virginia L. Wilson, Sarah M. Harvel, Alison M. Cartledge, Kaitlyn R. Bailey, Kathleen Mahon, Timothy Schuchard, Jen Humbert, Mark C. Hanson, Michael P. Cecil, James S. Abraham, Lorie Benedict, Claudia Slayton, Curtis S. Burnett, Rachel W. Ono-Lim, Sharon Budzinski, Shubi A. Khan, Sharon Goss, Terry Techmanski, Farida Valliani, Rimla Joseph, Edith Flores, Laurn Contreras, Ana Aguillon, Carrie-Ann Silvia, Maria Martin, Edmund K. Kerut, Leslie W. Levenson, Louis B. Glade, Brian J. Cospolich, Maureen W. Stein, Stephen P. LaGuardia, Thelma L. Sonza, Tracy M. Fife, Melissa Forschler, Jasmyne Watts, Judy Fritsch, Emese Futchko, Sarah Utech, Scott B. Baker, Miguel F. Roura, Scott A. Segel, James S. Magee, Cathy Jackson, Rebecca F. Goldfaden, Liudmila Quas, Elizabeth C. Ortiz, Michael Simpson, Robert Foster, Christopher Brian, James Trimm, Michael Bailey, Brian Snoddy, Van Reeder, Rachel Wilkinson, Harold Settle, Cynthia Massey, Angela Maiola, Michele Hall, Shelly Hall, Wanda Hall, Mark Xenakis, Janet Barrett, Giovanni Campanile, David Anthou, Susan F. Neill, Steven Karas, Enrique Polanco, Norberto Schechtman, Grace Tischner, Kay Warren, Cynthia St Cyr, Menna Kuczinski, Latrina Alexander, Maricruz Ibarra, Barry S. Horowitz, Jaime Steinsapir, Jeanette Mangual-Coughlin, Brittany Mooney, Precilia Vasquez, Kathleen Rodkey, Alexandria Biberstein, Christine Ignacio, Irina Robinson, Marcia Hibberd, Lisa B. Hoffman, Daniel J. Murak, Raghupathy Varavenkataraman, Theresa M. Ohlson Elliott, Linda A. Cunningham, Heather L. Palmerton, Sheri Poole, Jeannine Moore, Helene Wallace, Ted Chandler, Robert Riley, Farah Dawood, Amir Azeem, Michael Cammarata, Ashleigh Owen, Shivani Aggarwal, Waqas Qureshi, Mohamed Almahmoud, Abdullahi Oseni, Adam Leigh, Erin Barnes, Adam Pflum, Amer Aladin, Karen Blinson, Vickie Wayne, Lynda Doomy, Michele Wall, Valerie Bitterman, Cindi Young, Rachel Grice, Lioubov Poliakova, Jorge Davalos, David Rosenbaum, Mark Boulware, Heather Mazzola, J. Russell Strader, Russell Linsky, David Schwartz, Elizabeth Graf, Alicia Gneiting, Melissa Palmblad, Ashley Donlin, Emily Ensminger, Hillary Garcia, Dawn Robinson, Carolyn Tran, Jeffrey Jacqmein, Darlene Bartilucci, Michael Koren, Barbara Maluchnik, Melissa Parks, Jennifer Miller, Cynthia DeFosse, Albert B. Knouse, Amy Delancey, Stephanie Chin, Thomas Stephens, Mag Sohal, Juana Ingram, Swarooparani Kumar, Heather Foley, Nina Smith, Vera McKinney, Linda Schwarz, Judith Moore, Hildreth Vernon Anderson, Stefano Sdringola-Maranga, Ali Denktas, Elizabeth Turrentine, Rhonda Patterson, John Marshall, Terri Tolar, Donna Patrick, Pamela Schwartzkopf, Anthony M. Fletcher, Frances R. Harris, Sherry Clements, Tiffany Brown, William Smith, Stacey J. Baehl, Robin Fluty, Daniel VanHamersveld, Dennis Breen, Nancy Bender, Beverly Stafford, Tamika Washington, Margaret N. Pike, Mark A. Stich, Evyan Jawad, Amin Nadeem, Jill Nyland, Rhonda Hamer, Kendra Calhoun, Charlotte Mall, Samuel Cadogan, Kati Raynes, Richard Katz, Lorraine Marshall, Rashida Abbas, Jay L. Dinerman, John T. Hartley, Beth Lamb, Lisa Eskridge, Donna Raymond, Kristy Clemmer, Denise M. Fine, Paula Beardsley, Janet Werner, Bette Mahan, Courtney VanTol, Robert Herman, Christine Raiser-Vignola, Felicia McShan, Stefanie A. Neill, David R. Blick, Michael J. Liston, Denetta K. Nelson, Sandra K. Dorrell, Patricia Wyman, Ambereen Quraishi, Fernando Ferro, Frank Morris, Vicki J. Coombs, Autumn M. Mains, Austin A. Campbell, Jeanne Phelps, Cheryl A. Geary, Ellen G. Sheridan, Jean M. Downing, Arie Swatkowski, Tish Redden, Brian Dragutsky, Susan Thomas, Candace Mitchell, Diana Barker, Elanie Turcotte, Deborah Segerson, Jill Guy, Karena De La Mora, Jennifer Hong, Dennis Do, Rose Norris, Faisal Khan, Hector Montero, Stacy Kelly-White, Alan Cleland, Rosalyn Alcalde-Crawford, Melissa Morgan, Brijmohan Sarabu, Megan Minor, Shweta Kamat, Stephanie M. Estes, Nancee Harless, Alicia Disney, Jodi L. Pagano, Chad M. Alford, Noel W. Bedwell, Warren D. Hardy, Kevin DeAndrade, Jessica G. Elmore, Eric Auerbach, Anthony W. Haney, Miriam H. Brooks, Jose Torres, Lois Roper, Terry Backer, Katie Backer, John G. Evans, Ricardo A. Silva, Lorraine H. Dajani, Veronica Yousif, Tammy Ross, Sion K. Roy, Ronald Oudiz, Sajad Hamal, Ferdinand Flores, Amor Leahy, Debra Ayer, Swapna George, Chrisi Carine Stewart, Elvira Orellana, Cristina Boccalandro, Mary Rangel, Suzanne Hennings, Carl Vanselow, Teri Victor, Darlene Birdwell, Paul Haas, Anthony Sandoval, Gina Ciavarella, Caroline Saglam, Amy Bird, Keith Beck, Brian Poliquin, David Dominguez, Brittany Tenorio, Harvonya Perkins, Esther San Roman, Paris Bransford, Christy Lowrance, Marcy Broussard, Mary Ellis, Bobbi Skiles, Jessica Hamilton, Kathryn Hall, Diego Olvera, Julee A. Hartwell, Nevien Sorial, Mary Rickman, Kevin Berman, Nirav Mehta, Annie Laborin, Rodger Rothenberger, Sarah Beauvilliers, Kathy Morrell, Michael P. Schachter, Cindy L. Perkins, Elizabeth A. Gordon, Jennifer Lauer, Kim Bichsel, Kelly Oliver, Leslie J. Mellor, Candice Demattia, Jennifer Schomburg, Yenniffer Moreno, Eduardo Mansur-Garza, Lena Rippstein, Lorie Chacon, Andrea Pena, Michelle King, Susan Richardson, Annette Jessop, Nicole Tucker, Whitney Royer, Gilbert Templeton, Ann Moell, Christine Weller, Melissa J. Botts, Gretel Hollon, Elsa Homberg-Pinassi, Paula Forest, Aref Bin Abhulhak, Devona Chun-Furlong, Deborah Harrington, Emily Harlynn, Marjorie Schmitt, Constance Shelsky, Patricia Feldick, Mary Cherrico, Courtney Jagle, Nicholas Warnecke, Debra Myer, Deanna J. Ruder, Albina Underwood, Alan Rauba, George Carr, Barbara Oberhaus, Jessica Vanderfeltz, Mary Jo Stucky-Heil, Dale R. Gibson, Vonnie Fuentes, Kimberly L. Talbot, William C. Simon, Katlyn J. Grimes, Christina R. Wheeler, Cassaundra Shultz, Rhonda A. Metcalf, Jennifer L. Hill, Michelle R. Oliver, Basharat Ahmad, Fouzal Azeem, Abdul Rahim, George H. Freeman, Dawn Bloch, Heather Freeman, Jamie Brown, Sarah Rosbach, Pamela Melander, Nick Taralson, Alex Liu, Katlyn Harms, Mahfouz Michale, Jose Lopez, Maria Revoredo, Shari Edevane, Sarah Shawley, Timothy L. Jackson, Michael J. Oliver, Dina DeSalle, Patricia J. Matlock, Ionna M. Beraun, Heather Hendrix, Garrett Bromley, Ashley Niemerski, Gabby Teran, Sonia Guerrero, Murtaza Marvi, Zehra Palanpurwala, Andrea Torres, Patty Gloyd, Michelle Conger, Aziz Laurent, Olia Nayor, Catalina S. Villanueva, Munira Khambati, Tabetha J. Mumford, Melanie J. Castillo, Taddese Desta, Jerome Robinson, La Shawn Woods, Anita Bahri, Nancy Herrera, Cecilia Casaclang, Jeffrey R. Unger, Geraldine Martinez, Mia K. Moon, Stephen M. Mohaupt, Larry Sandoval, Louisito Valenzuela, Victora Ramirez, Nelly Mata, Veronica Avila, Marisol Patino, Cynthia Montano-Pereira, Omar Barnett, William M. Webster, Lorraine M. Christensen, Leighna Bofman, Melanie Livingston, Stacey Adams, Joseph Hobbs, Leesa Koskela, Mia Katz, Samuel Mujica-Trenche, Franklin Cala, Noreen T. Rana, Jennifer Scarlett, Milagros Cala Anaya, Marsha R. Jones, Kelly D. Hollis, Debbie Roth, Kristin Eads, Tina Watts, Judy Perkins, Alice Arnold, Daniel C. Ginsberg, Denise Quinn, Nicole Cureton, David B. Fittingoff, Mohammed I. Iqbal, Stephen R. White, Edith Sisneros, Michelle Ducca, David Streja, Danny Campos, Jennifer L. Boak, Farzeen Amir, Felice Anderson, James J. Kmetzo, Mary O. Bongarzone, Dawn Scott, Mary Grace De Leon, Cynthia Buda, William Graettinger, Michelle Alex, Erika Hess, James Govoni, Melissa Bartel, Travis L. Monchamp, Julie S. Roach, Sara Gibson, Amy M. Allfrey, Kristen Timpy, Kathy Bott, Karin A. Soucy, Jean Willis, Cecilia A. Valerio, Anusha Chunduri, Rebecca Coker, Nicole Vidrine, Ellen A. Thompson, Mark A. Studeny, Melissa K. Marcum, Tammy S. Monway, Douglas L. Kosmicki, Melissa J. Kelley, Corey M. Godfrey, Susan L. Krenk, Randy R. Holcomb, Deb K. Baehr, Mary K. Trauernicht, David Rowland Lowry, Betty Bondy Herts, Jeanne E Phelps, Jean-Marie Downing, Carol Gamer Dignon, Elisabeth S. Cockrill, Pravinchandra G. Chapla, Diane Fera, Margaret Chang, Patricia Fredette, Tamie Ashby, Renee Bergin, Zebediah A. Stearns, David B. Ware, Rachael M. Boudreaux, Joanna Rodriguez, Robert McKenzie, Amanda Huber, Rebecca Sommers, Heather Rowe, Stacy McLallen, Michale Haynes, Ashley Adamson, Janice Henderson, Lori McClure, Beverly A. Harris, Laura Ference, Sue Meissner-Dengler, Lisa Treasure, Doreen Nicely, Timothy L. Light, Tracey A. Osborn, Kimberly J. Mai, Pablo Vivas, Jose Rios, Dunia Rodriguez, Roger DeRaad, James Walder, Oscar Bailon, Denice Hockett, Debbie Anderson, Kelli McIntosh, Amber Odegard, Andrew Shepherd, Mary Seifert, Laurence Kelley, Rajendra Shetty, Michael Castine, David Brill, Gregory Fisher, Nicole Richmond, Kathleen Gray, Patricia Miller, Charlene Coneys, Yarixa Chanza, Monica Sumoza, Victoria M. Caudill, Kelly D. Harris, Courtney A. Manion, Melody J. Lineberger-Moore, Julie J. Wolfe, Barbara J. Rosen, Patricia DiVito, Janet L. Moffat, Christina Michaelis, Prashant Koshy, Diana Perea, Ghaith Al Yacoub, Stephanie Sadeghi, Thomas D. LeGalley, Rudolph F. Evonich, William J. Jean, Gary M. Friesen, John M. Pap, David A. Pesola, Mark D. Cowan, Kristofer M. Dosh, Dianna Larson, Adele M. Price, Jodi A. Nease, Jane E. Anderson, Lori A. Piggott, Robert Iwaoka, Kevin Sharkey, Edward McMillan, Laurie Lowder, Latisha Morgan, Kyle Davis, Tara Caldwell, Erica Breglio, Jasmine Summers, Rachel Poulimas, Muhammad Zahid, Hamid Syed, Maria Escobar, Jacob Levy, Rahma Warsi, Carol Ma, Puxiao Cen, Kimberly A. Cawthon, Delores B. Barnes, Deanna G. Allen, Margaret L. Warrington, Carol R. Stastny, Robin J. Michaels, Mohamad Saleh, John Sorin, Sunny Rathod, Urakay Juett, Steven Spencer, Aziza Keval, Jill McBride, Shane Young, Catherine Baxter, Carol Rasmussen, Shari L. Coxe, Luis Campos, Shahin Tavackoli, Diana Beckham, Darlynee Sanchez, Karanjit Basrai, Dorian Helms, Erica Clinton, Kasie Smith, Henry Cusnir, Mary Klaus Clark, Madhavagopal V. Cherukuri, Ameta Scarfaru, Stephen D. Nash, Loretta C. Grimm, Anna Grace, Kylie McElheran, Dino Subasic, Zedrick Buhay, Janet Litvinoff, Deepak Shah, Shannon Cervantes, Freda Usher, Farra Yasser, Theodore Trusevich, Ronnie L. Garcia, Jamison Wyatt, Rahul Bose, Holllilyn Miska, Traci Spivey, Amy B. Wren, Katie E. Vance, Lani L. Holman, Pam Gibbons, Elaine Eby, Sandra Shepard, Soratree Charoenthongtrakul, Brett Snodgrass, Mohammed Nazem, Shelly Keteenburg, Prathima Murthy, Frederic Prater, Ashley Rumfelt, Christina Eizensmits, Lisa Iannuzzi, Pourus R. Patel, Clellia Bergamino, Elizabeth McFeaters, Botros Rizk, Emiljia Pflaum, Danny Kalish, Rex Ambatali, Mona Ameli, Delaina Sanguinetti, Rakesh Vaidya, Martinus A.W. Broeders, Dorman Henrikus, Adrianus F.M. Kuijper, Nadea Al-Windy, Michael Magro, Karim Hamraoui, Ismail Aksoy, Guy L.J. Vermeiren, H.W.O. Roeters van Lennep, Gerard Hoedemaker, Johannes Jacobus Remmen, Kjell Bogaard, Dirk van der Heijden, Nicole MJ Knufman, Joost Frederiks, Johannes Willem Louwerenburg, Piet van Rossum, Johannes Milhous, Peter van der Meer, Arno van der Weerdt, Rob Breedveld, Mitran Keijzers, Walter Hermans, Ruud van de Wal, Peter A.G. Zwart, Marc M.J.M. van der Linden, Gerardus Zwiers, Dirk J. Boswijk, Jan Geert Tans, Jacob van Eck, Maarten V. Hessen, Barnabas J.B. Hamer, Stieneke Zoet-Nugteren, Lucien Theunissen, E.A. van Beek, Remco Nijmeijer, Pieter R. Nierop, Gerard Linssen, H.P. Swart, Timo Lenderink, Gerard L. Bartels, Frank den Hartog, Brian J. Berg van den, Wouter van Kempen, Susanne Kentgens, Gloria M. Rojas Lingan, Martinus M. Peeters, Hilligje Keterberg, Melchior Nierman, Annemieke K. den Hollander, Jacqueline Hoogendijk, Christine Voors-Pette, Vicdan Kose, Peter Viergever, Larysa Yena, Viktor Syvolap, Mykola P. Kopytsya, Olga Barna, Svitlana S. Panina, Mykhailo I. Lutai, Oxana V. Shershnyova, Iryna Luzkiv, Larysa S. Bula, Sergii Zotov, Ivan Vyjhovaniuk, Olena Lysunets, Volodymyr I. Koshlia, Nataliya Sydor, Myroslava F. Vayda, Olexiy Ushakov, Mykola Rishko, Viktor P. Shcherbak, Yevgeniya Svyshchenko, Vira Tseluyko, Andriy Yagensky, Viktoriia I. Zolotaikina, Olga Godlevska, Larysa Ivanova, Olena Koval, Olena I. Mitchenko, Galyna Y. Kardash, Yurii S. Rudyk, Mykola Stanislavchuk, Volodymyr Ivanovych Volkov, Olena G. Karlinskaya, Susanna A. Tykhonova, Nikolay Vatutin, Ganna Smirnova, Volodymyr M. Kovalenko, Viktor Lizogub, Denys Sebov, Oleksandr Dyadyk, Svetlana Andrievskaya, Mykola P. Krasko, Alexander N. Parkhomenko, Lidiya Horbach, Iryna G. Kupnovytska, Tetyana Pertseva, Oleksandr Karpenko, Dmytro Reshotko, Svitlana V. Zhurba, Leonid Rudenko, Viktoriia Yu Zharinova, Valerii B. Shatylo, Yuriy I. Karpenko, Mariya A. Orynchak, Tatiana R. Kameneva, Elena Zherlitsina, Diana N. Alpenidze, Grigoriy P. Arutyunov, Elena Baranova, Boris Bart, Dmitriy I. Belenkiy, Svetlana A. Boldueva, Elena A. Demchenko, Vera V. Eltishcheva, Alexander M. Gofman, Boris M. Goloshchekin, Ivan Gennadyevich Gordeev, Nikolay Gratsianskiy, Gadel Kamalov, Niyaz R. Khasanov, Irina M. Kholina, Zhanna D. Kobalava, Elena V. Kobeleva, Alexandra O. Konradi, Victor A. Kostenko, Andrey Dmitrievich Kuimov, Polina Y. Ermakova, Sofia K. Malyutina, Alexey V. Panov, Natalia V. Polezhaeva, Olga Reshetko, Nataliya P. Shilkina, Sergey B. Shustov, Elena A. Smolyarchuk, Raisa I. Stryuk, Elena Yurievnar Solovieva, Andrey V. Susekov, Natalia Vezikova, Svetlana N. Ivanova, Alexander A. Petrov, Vladimir O. Konstantinov, Alina S. Agafina, Victor Gurevich, Konstantin N. Zrazhevskiy, Tatiana V. Supryadkina, Nikita B. Perepech, Vadim L. Arkhipovskiy, Dmitry Yu Butko, Irina A. Zobenko, Olga V. Orlikova, Viktor Mordovin, Olga L. Barbarash, Anastasiya Lebedeva, Vladimir Nosov, Oleg V. Averkov, Elena P. Pavlikova, Yuri B. Karpov, Marina Lvovna Giorgadze, Oleg A. Khrustalev, Mikhail Arkhipov, Tatiana A. Raskina, Julia V. Shilko, Yulia Samoilova, Elena D. Kosmacheva, Sergey V. Nedogoda, Kathleen Coetzee, Lesley J. Burgess, F.C.R. Theron, Iftikhar O. Ebrahim, Gerbrand A. Haasbroek, Maria Pretorius, Julien S. Trokis, Dorothea V. Urbach, Mark J. Abelson, Adrian R. Horak, Aysha E. Badat, Ellen M. Makotoko, Hendrik Du Toit Theron, Padaruth Ramlachan, Clive H. Corbett, Ismail H. Mitha, Hendrik F.M. Nortje, Dirkie J. Jansen van Rensburg, Peter J. Sebastian, F.C.J. Bester, Louis J. van Zyl, Brian L. Rayner, Elżbieta Błach, Magda Dąbrowska, Grzegorz Kania, Agata E. Kelm-Warchol, Leszek P. Kinasz, Janusz Korecki, Mariusz Kruk, Ewa Laskowska-Derlaga, Andrzej Madej, Krzysztof Saminski, Katarzyna Wasilewska, Katarzyna Szymkowiak, Małgorzata Wojciechowska, Natalia Piorowska, Andrzej Dyczek, Rajpal K. Abhaichand, Ramesh B. Byrapaneni, Basavanagowdappa Hattur, Malipeddi Bhaskara Rao, Nitin Ghaisas, Sujit Shankar Kadam, Jugal B. Gupta, Santhosh M. Jayadev, V.A. Kothiwale, Atul Mathur, Vijay Bhaskar, Ravi K. Aluri, Udaya P. Ponangi, Mukesh K. Sarna, Sunil Sathe, Manish K. Sharma, Jilendra Pal Singh Sawhney, Chakrabhavi B. Keshavamurthy, Arun Srinivas, Hemant P. Thacker, A. Sharda, Johny Joseph, Sunil Dwivedi, Viswanathan Mohan, Rajendra K. Premchand, Jacques Bedard, Jean Bergeron, Ronald Collette, David Crowley, Richard Dumas, Sam Henein, Geoff Moran, William F. O’Mahony, Michael O’Mahony, Sammy Chan, Mark H. Sherman, Graham C. Wong, Brian D. Carlson, Milan K. Gupta, David Borts, Sean R. Peterson, Martyn Chilvers, Allan J. Kelly, Jean C. Gregoire, Simon Kouz, Josep Rodés Cabau, Minodora Andor, Mircea Cinteza, Radu Ciudin, Radu I. Cojan, Roxana O. Darabont, Dan-Lucian Dumitrascu, Carmen Fierbinteanu-Braticievici, Ana Gabriela Fruntelata, Constantin Militaru, Bogdon E. Minescu, Doina Luminita Serban, Florin Mitu, Dorel Nastase Melicovici, Ovidiu Petrascu, Octavian M. Pirvu, Cristian Podoleanu, Calin Pop, Rodica-Valentina V. Stanescu-Cioranu, Adrian Tase, Cristina Voiculet, Constantine N. Aroney, Anthony M. Dart, Timothy Davis, Karam Kostner, David N. O’Neal, Peter W. Purnell, Bhuwanendu B. Singh, David R. Sullivan, Peter Thompson, Gerald F. Watts, Adam F. Blenkhorn, John V. Amerena, Rafeeq Samie, Randall Hendriks, Joseph Proietto, Nikolai Petrovsky, Alan Whelan, David Colquhoun, Russell S. Scott, Simon C. Young, Tammy Pegg, Samuel JS Wilson, Andrew W. Hamer, Richard A. Luke, Hamish H. Hart, Gerard P. Devlin, Gerard T. Wilkins, Ian F. Ternouth, Samraj Nandra, Bruno S. Loeprich, Nicole McGrath, Stuart L. Tie, Rob J. Bos, Alexandra Wils, Tamara Jacobs, Erik A. Badings, Lillian A. Ebels-Tuinbeek, Mayke L. Scholten, Esther Bayraktar-Verver, Debby Zweers, Manoek Schiks, Carolien Kalkman, Tineke Tiemes, Jeanette Mulderij, Katarzyna Dabrowska, Wilma Wijnakker, Riny Van de Loo, Jeanne de Graauw, Giny Reijnierse, Mirjam van der Zeijst, Mariska Scholten, Henk R. Hofmeijer, Antoinette van Dijk-van der Zanden, Dineke J. van Belle, Jan Van Es, Gera Van Buchem, Wendy Zijda, Harald Verheij, Linnea Oldenhof-Janssen, Martina Bader, Marije Löwik, Sandra Stuij, Pascal Vantrimpont, Krista van Aken, Karen Hamilton, Han Blömer, Gabriela van Laerhoven, Raymond Tukkie, Maarten Janssen, Gerard Verdel, Jon Funke Küpper, Bob van Vlies, Caroline Kalkman, Joke Vooges, Marinella Vermaas, Rachel Langenberg, Niek Haenen, Frans Smeets, Arko Scheepmaker, Marcel Grosfeld, Ilvy Van Lieshout, Marleen van den Berg, Marian Wittekoek, Petra Mol, Antionette Stapel, Margaretha Sierevogel, Nancy van der Ven, Annemiek Berkelmans, Eric Viergever, Hanneke Kramer, Wilma Engelen, Karen V. Houwelingen, Thierry X. Wildbergh, Arend Mosterd, Coriet Hobé-Rap, Marjan van Doorn, Petra Bunschoten, Michel Freericks, Mireille Emans, Petra Den Boer-Penning, Els Verlek, Christine Freericks, Cornelis de Nooijer, Christina Welten, Ingrid Groenenberg, Claudia van der Horst, Esther Vonk, Geert Tjeerdsma, Gerard M. Jochemsen, Corinne van Daalen, Ingrid Y. Danse, Lucy Kuipers, Anke Pieterse, Antonius Oomen, Daan de Waard, Willem Jan Flu, Zusan Kromhout, Petra Van der Bij, Rob Feld, Brigitta Hessels-Linnemeijer, Rob Lardinois, Jan L. Posma, Zwanette R. Aukema-Wouda, Marjolijn Hendriks-van Woerden, Desiree van Wijk, Driek P. Beelen, Ingrid H. Hendriks, Jan J. Jonker, Stefanie Schipperen, Vicdan Köse, Gloria Rojas, Linda Goedhart, Hanneke van Meurs, Jacqueline Rijssemus, Lindy Swinkels-Diepenmaat, Marloes de Louw-Jansen, Dominique Bierens-Peters, Willem W. van Kempen, Marianne E. Wittekoek, Irmaina Agous, Geert Schenk, Janneke Wittekoek, Kevin Cox, Deborah F. Julia, Jan J.C. Jonker, Roel Janssen, Melchor Nierman, Hilligje Katerberg, Irene van der Haar, Willem W. Van Kempen, Taco van Mesdag, Leyda M. Alvarez Costa, Manon Schensema, Salomé Zweekhorst, Deborah Font Julia, Lauri Hanewinckel, Joyce Olsthoorn, Johan C. Berends, Arie C. van der Spek, Roy van der Berg, Rob J. Timmermann, Ingrid Boerema, Iryna Mudruk, Anna Khrystoforova, Serhii Kyselov, Yaroslava V. Hilova, Pavlo Logoida, Nataliia A. Sanina, Ilona P. Golikova, Olena O. Nemchyna, Ivan I. Isaichikov, Olga B. Potapova, Iurii V. Gura, Larysa Berestetska, Olena O. Kulianda, Oleksandr Tantsura, Oleksandr S. Kulbachuk, Volodymyr Petsentiy, Ihor Biskub, Tetyana Handych, Oleg Lagkuti, Alyna Gagarina, Taras Chendey, Oksana F. Bilonko, Olena Matova, Larysa Bezrodna, Olena Yarynkina, Tetiana Ovdiienko, Volodymyr Randchenko, Maryna Mospan, Olena Butko, Olga Romanenko, Mykhailo Pavelko, Iryna Sichkaruk, Svitlana O. Lazareva, Olena A. Kudryk, Inessa M. Koltsun, Tetiana Magdalits, Sergei Zadorozhniy, Kira Kompaniiets, Andrii Ivanov, Sergiy Romanenko, Pavlo Kaplan, Vadym Y. Romanov, Oksana P. Mykytyuk, Nataliia S. Zaitseva, Sergiy N. Pyvovar, Lyudmyla Burdeuna, Emerita Serdobinska, Tatiana I. Shevchenko, Igor I. Ivanytskyi, Olena V. Khyzhnyak, Nataliya Kalinkina, Olena Keting, Olena Sklyanna, Olga Kashanska, Anna Shevelok, Marina Khristichenko, Ievgenii Y. Titov, Danilenko O. Oleksander, Nataliia S. Polenova, Nataliia Altunina, Viktoriia Kororaieva, Stanislav Zborovskiy, Leonid Kholopov, Iurii Suliman, Lanna Lukashenko, Stanislav Shvaykin, Olexandr M. Glavatskiy, Roman O. Sychov, Roman L. Kulynych, Oleksandr A. Skarzhevskyi, Nataliia V. Dovgan, Marta Horbach, Olga Cherkasova, Iryna Tyshchenko, Liudmyla Todoriuk, Svitlana Kizim, Nataliia Brodi, Oleksandr Ivanko, Olga Garbarchuk, Liudmyla Alieksieieva, Tetiana L. Shandra, Olena Beregova, Larisa An Bodretska, Svitlana S. Naskalova, Ivanna A. Antoniuk-Shcheglova, Olena V. Bondarenko, Natalia G. Andreeva, Iryna I. Vakalyuk, Olha S. Chovganyuk, Nataliya R. Artemenko, Kiril A. Maltsev, Natalia Kalishevich, Natalia G. Kondratyeva, Svetlana A. Nikitina, Maria V. Martjanova, Anna V. Sokolova, Dmitrii O. Dragunov, Olga Kolesnik, Vera Larina, Oxana V. Tsygankova, Maria Ivanova, Illia A. Karpov, Elena M. Aronova, Ekaterina S. Vedernikova, Ekaterina I. Lubinskaya, Taras Y. Burak, Sergey I. Skichko, Farhad Rasulev, Ekaterina B. Soldatova, Alexander L. Fenin, Ilya I. Laptev, Elena E. Luchinkina, Alexandr Akatov, Natalia V. Polenova, Natalia N. Slavina, Irina N. Korovnika, Marina Yu Prochorova, Regina Shakirova, Elena N. Andreicheva, Olga A. Krasnova, Tinatin V. Lobzhanidze, Tatiana B. Dmitrova, Viktoriya V. Stakhiv, Maria I. Pechatnikova, Alexandra V. Panova, Maria Y. Tipikina, Oxana P. Rotar, Nikolay A. Bokovin, Saule K. Karabalieva, Farid Y. Tumarov, Elena V. Vasileva, Natalya Gennadevna Lozhkina, Ekaterina V. Filippova, Alisa I. Sharkaeva, Ekanerina V. Filippova Deilik, Natalia Yu Tolkacheva, Elena N. Domracheva, Andrey N. Ryabikov, Inga T. Abesadze, Marianna Z. Alugishvili, Elena P. Nikolaeva, Nadezda V. Smirnova, Valentina I. Rodionova, Polina V. Dolovstaya, Igor E. Yunonin, Sergey V. Kadin, Tatyana S. Sveklina, Anna V. Bushmanova, Elena L. Barkova, Irina S. Gomova, Yana V. Brytkova, Tatiana B. Ivanova, Marina Y. Zubareva, Inga Skopets, Lybov A. Galashevskaya, Emilia D. Butinskaya, Olga G. Gusarova, Natalia B. Kalishevich, Yana R. Pavlova, Marianna P Serebrenitskaya, Vitalina F. Grygorieva, Gulnara R. Kuchaeva, Inna A. Vasileva, Gulnara I. Ospanova, Yulia V. Vahrusheva, Irina A. Semenova, Irina E.E. Mikhailova, Olga O. Kvasova, Valeria D. Shurygina, Alexey E. Rivin, Alexey O. Savelyev, Alexey A. Savelyev, Olesya O. Milyaeva, Nadezhda N. Lapshina, Ninel A. Lantsova, Pavel V. Alexandrov, Evgeniy A. Orlikov, Alla Falkovskaya, Tatiana Ripp, Sergei Triss, Stanislav Pekarskiy, Sitkova Ekaterina, Evgeniya N. Zhuravleva, Olga Perova, Galina Kovaleva, Liubov Koroleva, Lydia Mishchenko, Boris P. Garshin, Svetlana A. Kutuzova, Lyudmila I. Provotorova, Igor P. Zadvorny, Olga V. Okhapkina, Anatoly O. Khrustalev, Tatiana Suvorova, Elena S. Shaf, Varvara A. Vershinina, Andrey A. Kozulin, Oxana A. Oleynik, Irina Y. Martynova, Natalia V. Kizhvatova, Alla S. Salasyuk, Vera V. Tsoma, Alla A. Ledyaeva, Elena V. Chumachek, S.C. Blignaut, Tersia Y. Alexander, Chano Du Plessis, Thirumani Govender, Samatha M. Du Toit, Leya Motala, Areesh Gassiep, Christina Naude (Smit), Marli Terblanche, Marlien Snoer (Kruger), Berenice Pillay, De Vries Basson, Marisa E. Theron, Bianca Fouche, Mareli E. Coetzee, Pieter Odendall, Frederik H. Van Wijk, Anna-Mari Conradie, Trudie Van der Westhuizen, Carine Tredoux, Mohamed S. Mookdam, Andie J. Van der Merwe, Karin Snyman, Gerda Smal, Yvonne De Jager, Thomas A. Mabin, Annusca King, Lindy L. Henley, Brenda M. Zwane, Jane Robinson, Marinda Karsten, Andonia M. Page, Valerie Nsabiyumva, Charmaine Krahenbuhl, Jaiprakash D. Patel, Yunus E. Motala, Ayesha Dawood, Nondumiso B. Koza, Lenore M.S. Peters, Shavashni Ramlachan, Wilhelm J. Bodenstein, Pierre Roux, Lizelle Fouche, Cecilia M. Boshoff, Haroon M. Mitha, Fathima Khan, Henry P. Cyster, Helen Cyster, E. C. Wessels, Florence J. Jacobs, Melanie A. Sebastian, Deborah A. Sebastian, Nadia Mahomed, Ignatius P. Immink, Celia Cotzee, Tanja Cronje, Madele Roscher, Maria Le Roux, Yvonne A. Trinder, Renata Wnętrzak-Michalska, Magdalena Piszczek, Andrzej Piela, Ewa Czernecka, Dorota Knychas, Alina Walczak, Izabella Gładysz, Katarzyna Filas, Ewelina Kiluk, Krzysztof Świgło, Iwona Jędrzejczyk, Kamila Łuczyńska, Katarzyna Tymendorf, Wojciech Piesiewicz, Wojciech L. Kinasz, Stefan Samborski, Ilona Bartuś, Gramzyna Latocha Korecka, Ewa Gulaj, Jolanta Sopa, Bogusław Derlaga, Marcin Baisiak, Allicia Kowalisko, Edyta Stainszewska-Marasazlek, Bartosz Szafran, Malgorzata Swiatkiewicz, Artur Racewicz, Sławomir Grycel, Jerzy Supronik, Sylwia Walendziuk, Magdalena Tarantowicz, Agata Stasiak, Anna Sidorowicz-Białynicka, Marek Dwojak, Ewa Jaźwińska-Tarnawska, Katarzyna Kupczyk, Kamila Martowska, Kamila Kulon, Katarzyna Gajda, Bivin Wilson, Krithika Velusamy, Swaidha S. Sadhiq, Bhavani Siddeshi, M. Bhanukumar, Abhishek Srivatsav, Madhan Ramesh, Sri Harsha Chalasani, Mini Johnson, Prashanth Gopu, Jeesa George, Sowmya Reddy, Swetha Tessy Thara Eleena, Damodara Rao Kodem, Haritha N. Nakkella, Padma Kumari Mandula, Anjan Kumar Vuriya, Syamala Rajana, Aruna Kale, Tiwari Rajeev, Raina Jain, Vipin Jain, Srilakshmi Mandayam Adhyapak, Lumin Sheeba, Uma C R, Ramya R, Aditya V. Kulkarni, M.S. Ganachari, Ruma Sambrekar, Mohammad Bilal, Kalyan Chakravarthy, Ravi Badhavath, Sravan Kumar, Meenakshi Simhadri, Farooque Salamuddin, Venkat Prasad, Vivek Dwivedi, Sudha Sarna, Tilak Arora, Deepak Chawla, Archana Sathe, Chaware Gayatree, Ajeet Nanda, Ram Avtar, Jyoti Sharma, Vaibhavi P S, Sasirekha D, Deepthi Kobbajji, Ramya Ningappa, Shwetha Shree, Chandrashekar K, Nandini M R, Sowjanya S, Devika I G, Yashaswini N, Sonika G, Rathna L, Priyanka R, Rupal J. Shrimanker, Lakshmi Vinutha Reddy, K. Sumathi, Babitha Devi, Bina N. Naik, Rohini Manjunath, Rajeshwari Ashok, Tony V. Kunjumon, Jesline Thomas, Shaik Samdhani, Kasthuri Selvam, Poongothai Subramani, Nandakumar Parthasarathy, Nirmal K. Bohra, Anvesh K. Gatla, Cheryl Horbatuk, Julie Sills, E B. Davey, Liz Paramonczyk, Olga Racanelli, Sandy Strybosch, Andre Belanger, Jean Palardy, Alicia Schiffrin, Sylvie Gauthier, Norman Kalyniuk, Shawn D. Whatley, Heather Lappala, Grishma Patel, Matthew Reeve, Catherine Moran, Jody Everitt, Teresa Ferrari, Christine Bouffard, Jirir Frohlich, Gordon Francis, John Mancini, Gregory Bondy, Debbie DeAngelis, Patricia Fulton, David W. Blank, Angela Lombardo, Mylène Roy, Jackie Chow, Hyman Fox, William J. Grootendorst, Angela Hutchinson, Sharon M. Chan, Christie Fitzgerald, Lynn Wilkins, Rebecca L. Raymond, Arlene Reyes, Lavoie Marc André, Denis Fortin, Hélène Ouimet, Thanh-Thao Tôn-Nu, Martine Dussureault, Marie-Hélène Blain, Madeleine Roy, Nathalie Kopajko, Chantal Fleury, Karine Maheux, Gabriela Valentina Ciobotaru, Maria C. Constantinescu, Carmen-Lucia Gherghinescu, Ana-Maria Avram, Ioan Manitiu, Aura Sinpetrean, Lucian Pop, Delia Lupu, Radu Usvat, Ana Petrisor, Nicoleta Dumitru, Camelia Moruju, Adelina Gheorghita, Magda V. Mitu, Cosmin Macarie, Ana Maria Pop, Maria-Catalina Diaconu, Iulia Grancea, Mihaela Cosma, Mihaela Crisan, Elizabeth Herron, Paul Nestel, Sally B. Kay, Kaye S. Carter, Imran Badshah, Ashley Makepeace, Jocelyn Drinkwater, Michelle England, Azette Rafei, Kylie Patterson, Alicia Jenkins, Sybil McAuley, Sue M. Kent, Joy E. Vibert, Leonie Perrett, Thomas David, Samantha L. Kaye, Monika O’Connor, Nimalie J. Perera, Nicole T. Lai, Kerry A. Kearins, Christinia Dicamillo, Heather Anderson, Louise Ferguson, Sharon D. Radtke, Charles T. Thamarappillil, Janice M. Boys, Anita K. Long, Toni Shanahan, Michael Nyguyen, Nicole Forrest, Gill Tulloch, Della Greenwell, Sarah L. Price, Aye N. Tint, Priya K. Sumithran, Tamara L. Debreceni, Lisa Walker, Mary Caruana, Kira Edwards, Maria Stathopoulos, Cilla Haywood, Dimitar Sajkov, Sharen Pringle, Anne Tabner, Kathrina Bartolay, Chamindi Abeyratne, Kylie Bragg, Patrick Mulhern, Peter Purnell, Lyn Williams, Jane Hamlyn, Aurelia Connelly, Jan Hoffman, Samantha Bailey, Jane Kerr, Zarnia Morrison, Sarah Maeder, Roberta McEwan, Prasanna Kunasekera, Patrice McGregor, Jo Young, Sharon Berry, Rick Cutfield, Michelle Choe, Catherine McNamara, Narrinder K. Shergill, Petra Crone, Miles G. Williams, Keith Dyson, Diana H. Schmid, Audrey C. Doak, Melissa Spooner, Colin Edwards, Anne Turner, Grainne M. McAnnalley, Raewyn A. Fisher, Fraser B. Hamilton, Denis H. Friedlander, Melissa R. Kirk, Jayne E. Scales, Marguerite A. McLelland, Neelam A. Dalman, Cathy E. Vickers, Carolyn Jackson, Wendy Coleman, Phillip I. Garden, and Wendy F. Arnold
Subjects: Male, medicine.medical_specialty, Rate ratio, Double-Blind Method, Ischemia, Risk Factors, Physiology (medical), Internal medicine, medicine, Clinical endpoint, Humans, Myocardial infarction, Coronary Artery Bypass, Stroke, Aged, business.industry, Unstable angina, Hazard ratio, Absolute risk reduction, Middle Aged, medicine.disease, Eicosapentaenoic Acid, Number needed to treat, Cardiology, Female, Cardiology and Cardiovascular Medicine, business
Abstract: Background: Despite advances in surgery and pharmacotherapy, there remains significant residual ischemic risk after coronary artery bypass grafting surgery. Methods: In REDUCE-IT (Reduction of Cardiovascular Events With Icosapent Ethyl–Intervention Trial), a multicenter, placebo-controlled, double-blind trial, statin-treated patients with controlled low-density lipoprotein cholesterol and mild to moderate hypertriglyceridemia were randomized to 4 g daily of icosapent ethyl or placebo. They experienced a 25% reduction in risk of a primary efficacy end point (composite of cardiovascular death, myocardial infarction, stroke, coronary revascularization, or hospitalization for unstable angina) and a 26% reduction in risk of a key secondary efficacy end point (composite of cardiovascular death, myocardial infarction, or stroke) when compared with placebo. The current analysis reports on the subgroup of patients from the trial with a history of coronary artery bypass grafting. Results: Of the 8179 patients randomized in REDUCE-IT, a total of 1837 (22.5%) had a history of coronary artery bypass grafting, with 897 patients randomized to icosapent ethyl and 940 to placebo. Baseline characteristics were similar between treatment groups. Randomization to icosapent ethyl was associated with a significant reduction in the primary end point (hazard ratio [HR], 0.76 [95% CI, 0.63–0.92]; P =0.004), in the key secondary end point (HR, 0.69 [95% CI, 0.56–0.87]; P =0.001), and in total (first plus subsequent or recurrent) ischemic events (rate ratio, 0.64 [95% CI, 0.50–0.81]; P =0.0002) compared with placebo. This yielded an absolute risk reduction of 6.2% (95% CI, 2.3%–10.2%) in first events, with a number needed to treat of 16 (95% CI, 10–44) during a median follow-up time of 4.8 years. Safety findings were similar to the overall study: beyond an increased rate of atrial fibrillation/flutter requiring hospitalization for at least 24 hours (5.0% vs 3.1%; P =0.03) and a nonsignificant increase in bleeding, occurrences of adverse events were comparable between groups. Conclusions: In REDUCE-IT patients with a history of coronary artery bypass grafting, treatment with icosapent ethyl was associated with significant reductions in first and recurrent ischemic events. Registration: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT01492361.
Published: 2021

2. Icosapent Ethyl Reduces Ischemic Events in Patients With a History of Previous Coronary Artery Bypass Grafting: REDUCE-IT CABG

Author: Verma, Subodh, primary, Bhatt, Deepak L., additional, Steg, Ph. Gabriel, additional, Miller, Michael, additional, Brinton, Eliot A., additional, Jacobson, Terry A., additional, Dhingra, Nitish K., additional, Ketchum, Steven B., additional, Juliano, Rebecca A., additional, Jiao, Lixia, additional, Doyle, Ralph T., additional, Granowitz, Craig, additional, Gibson, C. Michael, additional, Pinto, Duane, additional, Giugliano, Robert P., additional, Budoff, Matthew J., additional, Mason, R. Preston, additional, Tardif, Jean-Claude, additional, Ballantyne, Christie M., additional, Martens, Fabrice M.A.C., additional, Schut, Astrid, additional, Olshansky, Brian, additional, Chung, Mina, additional, Hallstrom, Al, additional, Pearce, Lesly, additional, Mehta, Cyrus, additional, Mukherjee, Rajat, additional, Chakrabarti, Anjan K., additional, Gelfand, Eli V., additional, Leary, Megan Carroll, additional, Pinto, Duane S., additional, Pride, Yuri B., additional, Ketchum, Steven, additional, Bhavanthula, Ramakrishna, additional, Chester, Gertrude, additional, Copland, Christina, additional, Diffin, Katelyn, additional, Doyle, Ralph, additional, Erz, Kurt, additional, Giaquinto, Alex, additional, Glanton, Paula, additional, Granger, Angela, additional, Iroudayassamy, Richard H., additional, Juliano, Rebecca, additional, Jin, James, additional, Klevak, Dimitry, additional, Panchal, Hardik, additional, Wang, Robert, additional, Wang, Shin-Ru, additional, Abate, Gerard, additional, Berry, Peggy J., additional, Braeckman, Rene, additional, Doogan, Declan, additional, Elson, Anne, additional, HauptmannBaker, Amy, additional, Lamela, Isabel, additional, Lubeck, Catherine, additional, Manku, Mehar, additional, Murphy, Sabina, additional, Sanford, Monica, additional, Stirtan, William, additional, Soni, Paresh, additional, Bastien, Arnaud, additional, Foster, Demetria, additional, Gascon, Evangelito, additional, Johnson, Judith, additional, Latona, Lasbert, additional, Liu, Gang, additional, Palleja, Sandra, additional, Sanjuan, Nelly, additional, Shi, Jimmy, additional, Stager, William, additional, Venkatakrishnan, Mukund, additional, Youssef-Agha, Ahmed, additional, Zhu, Julie, additional, Aertker, Leela, additional, Ankolekar, Suresh, additional, Goldberg, Lisa, additional, Rajicic, Natasa, additional, Shu, Jianfen, additional, Zou, Heng, additional, Mikhail, Magdy, additional, Dawood, Gamil, additional, Koshy, N. Mathew, additional, Mukherjee, Sandip K., additional, Abadier, Rafik, additional, Lawless, Andrea L., additional, McGuinn, William P., additional, Weintraub, Howard, additional, Rohr, Kathryn, additional, Claxton, Edmund, additional, Weiss, Robert J., additional, Klein, Terry D., additional, Nallasivan, Mani, additional, Crowley, Stephen, additional, King, Marilyn, additional, Alfieri, Anthony D., additional, Fitz-Patrick, David, additional, Loh, Irving, additional, Mayer, Nolan J., additional, Prashad, Rakesh, additional, Lederman, Samuel, additional, Weinstein, Debra, additional, Bays, Harold E., additional, Chu, Keith, additional, Maghsoudi, Alireza, additional, Thompson, Paul D., additional, Carstens, Jeff, additional, Chang, Anna, additional, Cohen, Kenneth R., additional, Dean, Julius, additional, Ellison, Howard S., additional, Erickson, Bernard, additional, Flores, Enrique A., additional, Gottlieb, Daniel W., additional, Grena, Paul, additional, Guyton, John R., additional, Jones, Peter H., additional, Joseph, John M., additional, Lepor, Norman E., additional, Lerman, Sam, additional, Matheney, Robert D., additional, Pacheco, Theodore R., additional, Russo, Michael B., additional, Rubino, John, additional, Pereira, Edward S., additional, Seals, Albert A., additional, Viera, Eduardo, additional, Steljes, Alan D., additional, Thompson, Jason, additional, Kapadia, Shaival, additional, McIvor, Michael, additional, Salazar, Jorge E., additional, Santiago, Jose O., additional, Vicari, Ralph, additional, Berk, Martin R., additional, Kaye, William A., additional, McKenzie, Marcus, additional, Podlecki, David, additional, Snyder, Brian D., additional, Nash, Stephen, additional, Herrington, David M., additional, Johnson, Wallace, additional, Lee, Joseph R., additional, Blonder, Ronald, additional, Patel, Alpa M., additional, Castello, Ramon, additional, Greco, Susan, additional, Kereiakes, Dean J., additional, Nadar, Venkatesh K., additional, Nathan, Mark, additional, Potu, Ranganatha P., additional, Sangrigoli, Robert, additional, Smalling, Richard, additional, Davis, Mitchell, additional, Braastad, Robert, additional, McCriskin, James, additional, Bodiwala, Kunal, additional, Hargrove, Joe L., additional, Graves, Mark W., additional, Emlein, George, additional, Durant, Raegan W., additional, Clower, James W., additional, Arora, Rohit, additional, Singh, Narendra, additional, Warsinger Martin, Lisa, additional, Haught, W Herbert, additional, Litt, Marc P., additional, Klein, Michael D., additional, Hoagland, Peter, additional, Goldstein, Michael, additional, Mazzella, Marco S., additional, Dunker, Daniel H., additional, Kahn, Brian H., additional, Ince, Carlos S., additional, McGrew, Frank A., additional, Lee, Jay, additional, Pan, David, additional, Khan, Salman A., additional, Elkayam, Uri, additional, Deeb, Wasim, additional, Goldberg, Anne C., additional, Brown, Christopher S., additional, Leimbach, Wayne N., additional, Backer, Thomas S., additional, Sutton, David R., additional, Gellman, Joel, additional, George, Anu R., additional, Hoffman, Alan S., additional, Kates, Mark, additional, Anand, Kishlay, additional, Bear, Robert, additional, Cavanaugh, Brendan J., additional, Reyes, Ramon G., additional, Sotolongo, Rodolfo, additional, Sabatino, Kenneth, additional, Gallagher, Kevin, additional, Sorial, Ehab, additional, Geohas, Chris, additional, Magness, Kathleen E., additional, Grunstra, Bernard P., additional, Martin, Frederik A., additional, Knapp, William S., additional, Lucas, Mel E., additional, Champlin, John J., additional, Demattia, Jason, additional, Peters, Patrick H., additional, Kirstein, Judith, additional, Randall, William J., additional, Staniloae, Cezar S., additional, Robinson, Jennifer G., additional, Adler, Alexander, additional, Case, Christopher, additional, Kaplan, Andrew J., additional, Lakin, Gregory F., additional, Goyle, Krishan K., additional, DiGiovanna, Michael J., additional, Fisher, Chester L., additional, Lillestol, Michael, additional, Robinson, Michael, additional, Perry, Robert G., additional, Levinson, Lawrence S., additional, Everhart, Brian G., additional, Madder, Robert D., additional, Martin, Earl F., additional, Martin, Earl E., additional, Alam, Imtiaz, additional, Elacion, Jose Mari L., additional, Poonawala, Robina, additional, Desta, Taddese T., additional, Robinson, Jerome A., additional, Martinez, Gilbert J., additional, Reddy, Jakkidi S., additional, Wayne, Jeffrey D., additional, Mujica Trenche, Samuel, additional, Kaplan, Westbrook I., additional, Saavedra, Rubin H., additional, DiGregorio, Michael D., additional, Bertolet, Barry D., additional, Fraser, Neil J., additional, Hart, Terence T., additional, Graf, Ronald J., additional, Jasper, David A., additional, Dunn, Michael, additional, Streja, Dan A., additional, Strobl, David J., additional, Jiang, Nan, additional, Kalen, Vicki, additional, Mascolo, Richard, additional, Samson, Mercedes B., additional, Stephens, Michael, additional, Bellard, Bret M., additional, Juarez, Mario, additional, McCarthy, Patrick J., additional, Checton, John B., additional, Stillabower, Michael, additional, Goldenberg, Edward, additional, Karim, Amin H., additional, Jaffrani, Naseem, additional, Touchon, Robert C., additional, Fruehling, Erich R., additional, Friesen, Clayton J., additional, Chaudhuri, Pradipta, additional, Morris, Frank H., additional, Broker, Robert E., additional, Patel, Rajesh J., additional, Hole, Susan, additional, Miller, Randall P., additional, Miranda, Francisco G., additional, Dar, Sadia, additional, Gentry, Shawn N., additional, Hermany, Paul, additional, Treasure, Charles B., additional, Trevino, Miguel E., additional, Acosta, Raimundo, additional, Japour, Anthony, additional, Durr, Samuel J., additional, Wang, Thomas, additional, Ganda, Om P., additional, Krichmar, Perry, additional, Arter, James L., additional, Jacoby, Douglas, additional, Schwartz, Michael A., additional, Al-Karadsheh, Amer, additional, Gencheff, Nelson E., additional, Pasquini, John A., additional, Dunbar, Richard, additional, Kohnstamm, Sarah, additional, Lozano, Hector F., additional, Welty, Francine K., additional, Pitts, Thomas L., additional, Zehnder, Brian, additional, El Hafi, Salah, additional, King, Mark A., additional, Ghitis, Arnold, additional, Bahu, Marwan M., additional, Ranjbaran Jahromi, Hooman, additional, Caputo, Ronald P., additional, Busch, Robert S., additional, Shapiro, Michael D., additional, Zavaro, Suhail, additional, Daudjee, Munib, additional, Jacobs, Shahram, additional, Shah, Vipul B., additional, Rubalcava, Frank, additional, Alhaddad, Mohsin T., additional, Lui, Henry, additional, Rajan, Raj T., additional, Saba, Fadi E., additional, Gunapooti, Mahendra Pai N, additional, Kayembe, Tshiswaka B., additional, Jennings, Timothy, additional, Strzinek, Robert A., additional, Shanik, Michael H., additional, Singh, Pradeep K., additional, Kennedy, Alastair C., additional, Rubenstein, Howard, additional, Manshadi, Ramin, additional, Ladner, Joanne, additional, Kakish, Lily, additional, Kakish, Ashley, additional, Little, Amy L., additional, Gerber, Jaime, additional, Hinchion, Nancy J., additional, Guarino, Janet, additional, Raychok, Denise, additional, Budzinski, Susan, additional, Kelley-Garvin, Kathleen, additional, Beckord, April, additional, Schlinder, Jessica, additional, Schwartzbard, Arthur, additional, Cobos, Stanley, additional, Freeman, Deborah, additional, Abisalih, David, additional, McCann, Dervilla, additional, Guy, Kylie, additional, Chase, Jennifer, additional, Samuelson, Stacey, additional, Cassidy, Madeline, additional, Tardif, Marissa, additional, Smith, Jaime, additional, Sprout, Brenna, additional, Riedeman, Nanette, additional, Goza, Julie, additional, Johnson, Lori, additional, Kraske, Chad, additional, Hastings, Sheila, additional, Dutka, Chris, additional, Smith, Stephanie, additional, McCabe, Toni, additional, Maloney, Kathleen, additional, Alfieri, Paul, additional, Hosemane, Vinay, additional, Syravanh, Chanhsamone, additional, Pau, Cindy, additional, Limcoiloc, April, additional, Carreira, Tabitha, additional, Kurosawa, Taryn S., additional, Krumian, Razmig, additional, Preston, Krista, additional, Nashed, Ashraf, additional, Schneidman-Fernandez, Daria, additional, Patterson, Jack, additional, Tsakonas, John, additional, Esaki, Jennifer, additional, Sprafka, Lynn, additional, Patel, Porous, additional, Mitchell, Brian, additional, Ross, Erin M., additional, Miller, Donna, additional, Prashad, Akash, additional, Feyler, Kristina M., additional, Juarbe, Natasha, additional, Herrera, Sandra, additional, Keiran, Sarah M., additional, Whitehead, Becky, additional, Asher, Whitney, additional, Hobbs, Coury, additional, Elie, Abbey, additional, Brooks, Jean, additional, Zaleski, Amanda L., additional, Foxen, Brenda, additional, Lapke, Barb, additional, Wright, Philippa, additional, Pavol, Bristol, additional, Carangi, Gwen, additional, Turner, Marla, additional, Sanders, Katharine W., additional, Delamar, Rikita S., additional, Wilson, Virginia L., additional, Harvel, Sarah M., additional, Cartledge, Alison M., additional, Bailey, Kaitlyn R., additional, Mahon, Kathleen, additional, Schuchard, Timothy, additional, Humbert, Jen, additional, Hanson, Mark C., additional, Cecil, Michael P., additional, Abraham, James S., additional, Benedict, Lorie, additional, Slayton, Claudia, additional, Burnett, Curtis S., additional, Ono-Lim, Rachel W., additional, Budzinski, Sharon, additional, Khan, Shubi A., additional, Goss, Sharon, additional, Techmanski, Terry, additional, Valliani, Farida, additional, Joseph, Rimla, additional, Flores, Edith, additional, Contreras, Laurn, additional, Aguillon, Ana, additional, Silvia, Carrie-Ann, additional, Martin, Maria, additional, Kerut, Edmund K., additional, Levenson, Leslie W., additional, Glade, Louis B., additional, Cospolich, Brian J., additional, Stein, Maureen W., additional, LaGuardia, Stephen P., additional, Sonza, Thelma L., additional, Fife, Tracy M., additional, Forschler, Melissa, additional, Watts, Jasmyne, additional, Fritsch, Judy, additional, Futchko, Emese, additional, Utech, Sarah, additional, Baker, Scott B., additional, Roura, Miguel F., additional, Segel, Scott A., additional, Magee, James S., additional, Jackson, Cathy, additional, Goldfaden, Rebecca F., additional, Quas, Liudmila, additional, Ortiz, Elizabeth C., additional, Simpson, Michael, additional, Foster, Robert, additional, Brian, Christopher, additional, Trimm, James, additional, Bailey, Michael, additional, Snoddy, Brian, additional, Reeder, Van, additional, Wilkinson, Rachel, additional, Settle, Harold, additional, Massey, Cynthia, additional, Maiola, Angela, additional, Hall, Michele, additional, Hall, Shelly, additional, Hall, Wanda, additional, Xenakis, Mark, additional, Barrett, Janet, additional, Campanile, Giovanni, additional, Anthou, David, additional, Neill, Susan F., additional, Karas, Steven, additional, Polanco, Enrique, additional, Schechtman, Norberto, additional, Tischner, Grace, additional, Warren, Kay, additional, St Cyr, Cynthia, additional, Kuczinski, Menna, additional, Alexander, Latrina, additional, Ibarra, Maricruz, additional, Horowitz, Barry S., additional, Steinsapir, Jaime, additional, Mangual-Coughlin, Jeanette, additional, Mooney, Brittany, additional, Vasquez, Precilia, additional, Rodkey, Kathleen, additional, Biberstein, Alexandria, additional, Ignacio, Christine, additional, Robinson, Irina, additional, Hibberd, Marcia, additional, Hoffman, Lisa B., additional, Murak, Daniel J., additional, Varavenkataraman, Raghupathy, additional, Ohlson Elliott, Theresa M., additional, Cunningham, Linda A., additional, Palmerton, Heather L., additional, Poole, Sheri, additional, Moore, Jeannine, additional, Wallace, Helene, additional, Chandler, Ted, additional, Riley, Robert, additional, Dawood, Farah, additional, Azeem, Amir, additional, Cammarata, Michael, additional, Owen, Ashleigh, additional, Aggarwal, Shivani, additional, Qureshi, Waqas, additional, Almahmoud, Mohamed, additional, Oseni, Abdullahi, additional, Leigh, Adam, additional, Barnes, Erin, additional, Pflum, Adam, additional, Aladin, Amer, additional, Blinson, Karen, additional, Wayne, Vickie, additional, Doomy, Lynda, additional, Wall, Michele, additional, Bitterman, Valerie, additional, Young, Cindi, additional, Grice, Rachel, additional, Poliakova, Lioubov, additional, Davalos, Jorge, additional, Rosenbaum, David, additional, Boulware, Mark, additional, Mazzola, Heather, additional, Strader, J. Russell, additional, Linsky, Russell, additional, Schwartz, David, additional, Graf, Elizabeth, additional, Gneiting, Alicia, additional, Palmblad, Melissa, additional, Donlin, Ashley, additional, Ensminger, Emily, additional, Garcia, Hillary, additional, Robinson, Dawn, additional, Tran, Carolyn, additional, Jacqmein, Jeffrey, additional, Bartilucci, Darlene, additional, Koren, Michael, additional, Maluchnik, Barbara, additional, Parks, Melissa, additional, Miller, Jennifer, additional, DeFosse, Cynthia, additional, Knouse, Albert B., additional, Delancey, Amy, additional, Chin, Stephanie, additional, Stephens, Thomas, additional, Sohal, Mag, additional, Ingram, Juana, additional, Kumar, Swarooparani, additional, Foley, Heather, additional, Smith, Nina, additional, McKinney, Vera, additional, Schwarz, Linda, additional, Moore, Judith, additional, Anderson, Hildreth Vernon, additional, Sdringola-Maranga, Stefano, additional, Denktas, Ali, additional, Turrentine, Elizabeth, additional, Patterson, Rhonda, additional, Marshall, John, additional, Tolar, Terri, additional, Patrick, Donna, additional, Schwartzkopf, Pamela, additional, Fletcher, Anthony M., additional, Harris, Frances R., additional, Clements, Sherry, additional, Brown, Tiffany, additional, Smith, William, additional, Baehl, Stacey J., additional, Fluty, Robin, additional, VanHamersveld, Daniel, additional, Breen, Dennis, additional, Bender, Nancy, additional, Stafford, Beverly, additional, Washington, Tamika, additional, Pike, Margaret N., additional, Stich, Mark A., additional, Jawad, Evyan, additional, Nadeem, Amin, additional, Nyland, Jill, additional, Hamer, Rhonda, additional, Calhoun, Kendra, additional, Mall, Charlotte, additional, Cadogan, Samuel, additional, Raynes, Kati, additional, Katz, Richard, additional, Marshall, Lorraine, additional, Abbas, Rashida, additional, Dinerman, Jay L., additional, Hartley, John T., additional, Lamb, Beth, additional, Eskridge, Lisa, additional, Raymond, Donna, additional, Clemmer, Kristy, additional, Fine, Denise M., additional, Beardsley, Paula, additional, Werner, Janet, additional, Mahan, Bette, additional, VanTol, Courtney, additional, Herman, Robert, additional, Raiser-Vignola, Christine, additional, McShan, Felicia, additional, Neill, Stefanie A., additional, Blick, David R., additional, Liston, Michael J., additional, Nelson, Denetta K., additional, Dorrell, Sandra K., additional, Wyman, Patricia, additional, Quraishi, Ambereen, additional, Ferro, Fernando, additional, Morris, Frank, additional, Coombs, Vicki J., additional, Mains, Autumn M., additional, Campbell, Austin A., additional, Phelps, Jeanne, additional, Geary, Cheryl A., additional, Sheridan, Ellen G., additional, Downing, Jean M., additional, Swatkowski, Arie, additional, Redden, Tish, additional, Dragutsky, Brian, additional, Thomas, Susan, additional, Mitchell, Candace, additional, Barker, Diana, additional, Turcotte, Elanie, additional, Segerson, Deborah, additional, Guy, Jill, additional, De La Mora, Karena, additional, Hong, Jennifer, additional, Do, Dennis, additional, Norris, Rose, additional, Khan, Faisal, additional, Montero, Hector, additional, Kelly-White, Stacy, additional, Cleland, Alan, additional, Alcalde-Crawford, Rosalyn, additional, Morgan, Melissa, additional, Sarabu, Brijmohan, additional, Minor, Megan, additional, Kamat, Shweta, additional, Estes, Stephanie M., additional, Harless, Nancee, additional, Disney, Alicia, additional, Pagano, Jodi L., additional, Alford, Chad M., additional, Bedwell, Noel W., additional, Hardy, Warren D., additional, DeAndrade, Kevin, additional, Elmore, Jessica G., additional, Auerbach, Eric, additional, Haney, Anthony W., additional, Brooks, Miriam H., additional, Torres, Jose, additional, Roper, Lois, additional, Backer, Terry, additional, Backer, Katie, additional, Evans, John G., additional, Silva, Ricardo A., additional, Dajani, Lorraine H., additional, Yousif, Veronica, additional, Ross, Tammy, additional, Roy, Sion K., additional, Oudiz, Ronald, additional, Hamal, Sajad, additional, Flores, Ferdinand, additional, Leahy, Amor, additional, Ayer, Debra, additional, George, Swapna, additional, Stewart, Chrisi Carine, additional, Orellana, Elvira, additional, Boccalandro, Cristina, additional, Rangel, Mary, additional, Hennings, Suzanne, additional, Vanselow, Carl, additional, Victor, Teri, additional, Birdwell, Darlene, additional, Haas, Paul, additional, Sandoval, Anthony, additional, Ciavarella, Gina, additional, Saglam, Caroline, additional, Bird, Amy, additional, Beck, Keith, additional, Poliquin, Brian, additional, Dominguez, David, additional, Tenorio, Brittany, additional, Perkins, Harvonya, additional, San Roman, Esther, additional, Bransford, Paris, additional, Lowrance, Christy, additional, Broussard, Marcy, additional, Ellis, Mary, additional, Skiles, Bobbi, additional, Hamilton, Jessica, additional, Hall, Kathryn, additional, Olvera, Diego, additional, Hartwell, Julee A., additional, Sorial, Nevien, additional, Rickman, Mary, additional, Berman, Kevin, additional, Mehta, Nirav, additional, Laborin, Annie, additional, Rothenberger, Rodger, additional, Beauvilliers, Sarah, additional, Morrell, Kathy, additional, Schachter, Michael P., additional, Perkins, Cindy L., additional, Gordon, Elizabeth A., additional, Lauer, Jennifer, additional, Bichsel, Kim, additional, Oliver, Kelly, additional, Mellor, Leslie J., additional, Demattia, Candice, additional, Schomburg, Jennifer, additional, Moreno, Yenniffer, additional, Mansur-Garza, Eduardo, additional, Rippstein, Lena, additional, Chacon, Lorie, additional, Pena, Andrea, additional, King, Michelle, additional, Richardson, Susan, additional, Jessop, Annette, additional, Tucker, Nicole, additional, Royer, Whitney, additional, Templeton, Gilbert, additional, Moell, Ann, additional, Weller, Christine, additional, Botts, Melissa J., additional, Hollon, Gretel, additional, Homberg-Pinassi, Elsa, additional, Forest, Paula, additional, Abhulhak, Aref Bin, additional, Chun-Furlong, Devona, additional, Harrington, Deborah, additional, Harlynn, Emily, additional, Schmitt, Marjorie, additional, Shelsky, Constance, additional, Feldick, Patricia, additional, Cherrico, Mary, additional, Jagle, Courtney, additional, Warnecke, Nicholas, additional, Myer, Debra, additional, Ruder, Deanna J., additional, Underwood, Albina, additional, Rauba, Alan, additional, Carr, George, additional, Oberhaus, Barbara, additional, Vanderfeltz, Jessica, additional, Stucky-Heil, Mary Jo, additional, Gibson, Dale R., additional, Fuentes, Vonnie, additional, Talbot, Kimberly L., additional, Simon, William C., additional, Grimes, Katlyn J., additional, Wheeler, Christina R., additional, Shultz, Cassaundra, additional, Metcalf, Rhonda A., additional, Hill, Jennifer L., additional, Oliver, Michelle R., additional, Ahmad, Basharat, additional, Azeem, Fouzal, additional, Rahim, Abdul, additional, Freeman, George H., additional, Bloch, Dawn, additional, Freeman, Heather, additional, Brown, Jamie, additional, Rosbach, Sarah, additional, Melander, Pamela, additional, Taralson, Nick, additional, Liu, Alex, additional, Harms, Katlyn, additional, Michale, Mahfouz, additional, Lopez, Jose, additional, Revoredo, Maria, additional, Edevane, Shari, additional, Shawley, Sarah, additional, Jackson, Timothy L., additional, Oliver, Michael J., additional, DeSalle, Dina, additional, Matlock, Patricia J., additional, Beraun, Ionna M., additional, Hendrix, Heather, additional, Bromley, Garrett, additional, Niemerski, Ashley, additional, Teran, Gabby, additional, Guerrero, Sonia, additional, Marvi, Murtaza, additional, Palanpurwala, Zehra, additional, Torres, Andrea, additional, Gloyd, Patty, additional, Conger, Michelle, additional, Laurent, Aziz, additional, Nayor, Olia, additional, Villanueva, Catalina S., additional, Khambati, Munira, additional, Mumford, Tabetha J., additional, Castillo, Melanie J., additional, Desta, Taddese, additional, Robinson, Jerome, additional, Woods, La Shawn, additional, Bahri, Anita, additional, Herrera, Nancy, additional, Casaclang, Cecilia, additional, Unger, Jeffrey R., additional, Martinez, Geraldine, additional, Moon, Mia K., additional, Mohaupt, Stephen M., additional, Sandoval, Larry, additional, Valenzuela, Louisito, additional, Ramirez, Victora, additional, Mata, Nelly, additional, Avila, Veronica, additional, Patino, Marisol, additional, Montano-Pereira, Cynthia, additional, Barnett, Omar, additional, Webster, William M., additional, Christensen, Lorraine M., additional, Bofman, Leighna, additional, Livingston, Melanie, additional, Adams, Stacey, additional, Hobbs, Joseph, additional, Koskela, Leesa, additional, Katz, Mia, additional, Mujica-Trenche, Samuel, additional, Cala, Franklin, additional, Rana, Noreen T., additional, Scarlett, Jennifer, additional, Cala Anaya, Milagros, additional, Jones, Marsha R., additional, Hollis, Kelly D., additional, Roth, Debbie, additional, Eads, Kristin, additional, Watts, Tina, additional, Perkins, Judy, additional, Arnold, Alice, additional, Ginsberg, Daniel C., additional, Quinn, Denise, additional, Cureton, Nicole, additional, Fittingoff, David B., additional, Iqbal, Mohammed I., additional, White, Stephen R., additional, Sisneros, Edith, additional, Ducca, Michelle, additional, Streja, David, additional, Campos, Danny, additional, Boak, Jennifer L., additional, Amir, Farzeen, additional, Anderson, Felice, additional, Kmetzo, James J., additional, Bongarzone, Mary O., additional, Scott, Dawn, additional, De Leon, Mary Grace, additional, Buda, Cynthia, additional, Graettinger, William, additional, Alex, Michelle, additional, Hess, Erika, additional, Govoni, James, additional, Bartel, Melissa, additional, Monchamp, Travis L., additional, Roach, Julie S., additional, Gibson, Sara, additional, Allfrey, Amy M., additional, Timpy, Kristen, additional, Bott, Kathy, additional, Soucy, Karin A., additional, Willis, Jean, additional, Valerio, Cecilia A., additional, Chunduri, Anusha, additional, Coker, Rebecca, additional, Vidrine, Nicole, additional, Thompson, Ellen A., additional, Studeny, Mark A., additional, Marcum, Melissa K., additional, Monway, Tammy S., additional, Kosmicki, Douglas L., additional, Kelley, Melissa J., additional, Godfrey, Corey M., additional, Krenk, Susan L., additional, Holcomb, Randy R., additional, Baehr, Deb K., additional, Trauernicht, Mary K., additional, Rowland Lowry, David, additional, Bondy Herts, Betty, additional, Phelps, Jeanne E, additional, Downing, Jean-Marie, additional, Gamer Dignon, Carol, additional, Cockrill, Elisabeth S., additional, Chapla, Pravinchandra G., additional, Fera, Diane, additional, Chang, Margaret, additional, Fredette, Patricia, additional, Ashby, Tamie, additional, Bergin, Renee, additional, Stearns, Zebediah A., additional, Ware, David B., additional, Boudreaux, Rachael M., additional, Rodriguez, Joanna, additional, McKenzie, Robert, additional, Huber, Amanda, additional, Sommers, Rebecca, additional, Rowe, Heather, additional, McLallen, Stacy, additional, Haynes, Michale, additional, Adamson, Ashley, additional, Henderson, Janice, additional, McClure, Lori, additional, Harris, Beverly A., additional, Ference, Laura, additional, Meissner-Dengler, Sue, additional, Treasure, Lisa, additional, Nicely, Doreen, additional, Light, Timothy L., additional, Osborn, Tracey A., additional, Mai, Kimberly J., additional, Vivas, Pablo, additional, Rios, Jose, additional, Rodriguez, Dunia, additional, DeRaad, Roger, additional, Walder, James, additional, Bailon, Oscar, additional, Hockett, Denice, additional, Anderson, Debbie, additional, McIntosh, Kelli, additional, Odegard, Amber, additional, Shepherd, Andrew, additional, Seifert, Mary, additional, Kelley, Laurence, additional, Shetty, Rajendra, additional, Castine, Michael, additional, Brill, David, additional, Fisher, Gregory, additional, Richmond, Nicole, additional, Gray, Kathleen, additional, Miller, Patricia, additional, Coneys, Charlene, additional, Chanza, Yarixa, additional, Sumoza, Monica, additional, Caudill, Victoria M., additional, Harris, Kelly D., additional, Manion, Courtney A., additional, Lineberger-Moore, Melody J., additional, Wolfe, Julie J., additional, Rosen, Barbara J., additional, DiVito, Patricia, additional, Moffat, Janet L., additional, Michaelis, Christina, additional, Koshy, Prashant, additional, Perea, Diana, additional, Al Yacoub, Ghaith, additional, Sadeghi, Stephanie, additional, LeGalley, Thomas D., additional, Evonich, Rudolph F., additional, Jean, William J., additional, Friesen, Gary M., additional, Pap, John M., additional, Pesola, David A., additional, Cowan, Mark D., additional, Dosh, Kristofer M., additional, Larson, Dianna, additional, Price, Adele M., additional, Nease, Jodi A., additional, Anderson, Jane E., additional, Piggott, Lori A., additional, Iwaoka, Robert, additional, Sharkey, Kevin, additional, McMillan, Edward, additional, Lowder, Laurie, additional, Morgan, Latisha, additional, Davis, Kyle, additional, Caldwell, Tara, additional, Breglio, Erica, additional, Summers, Jasmine, additional, Poulimas, Rachel, additional, Zahid, Muhammad, additional, Syed, Hamid, additional, Escobar, Maria, additional, Levy, Jacob, additional, Warsi, Rahma, additional, Ma, Carol, additional, Cen, Puxiao, additional, Cawthon, Kimberly A., additional, Barnes, Delores B., additional, Allen, Deanna G., additional, Warrington, Margaret L., additional, Stastny, Carol R., additional, Michaels, Robin J., additional, Saleh, Mohamad, additional, Sorin, John, additional, Rathod, Sunny, additional, Juett, Urakay, additional, Spencer, Steven, additional, Keval, Aziza, additional, McBride, Jill, additional, Young, Shane, additional, Baxter, Catherine, additional, Rasmussen, Carol, additional, Coxe, Shari L., additional, Campos, Luis, additional, Tavackoli, Shahin, additional, Beckham, Diana, additional, Sanchez, Darlynee, additional, Basrai, Karanjit, additional, Helms, Dorian, additional, Clinton, Erica, additional, Smith, Kasie, additional, Cusnir, Henry, additional, Klaus Clark, Mary, additional, Cherukuri, Madhavagopal V., additional, Scarfaru, Ameta, additional, Nash, Stephen D., additional, Grimm, Loretta C., additional, Grace, Anna, additional, McElheran, Kylie, additional, Subasic, Dino, additional, Buhay, Zedrick, additional, Litvinoff, Janet, additional, Shah, Deepak, additional, Cervantes, Shannon, additional, Usher, Freda, additional, Yasser, Farra, additional, Trusevich, Theodore, additional, Garcia, Ronnie L., additional, Wyatt, Jamison, additional, Bose, Rahul, additional, Miska, Holllilyn, additional, Spivey, Traci, additional, Wren, Amy B., additional, Vance, Katie E., additional, Holman, Lani L., additional, Gibbons, Pam, additional, Eby, Elaine, additional, Shepard, Sandra, additional, Charoenthongtrakul, Soratree, additional, Snodgrass, Brett, additional, Nazem, Mohammed, additional, Keteenburg, Shelly, additional, Murthy, Prathima, additional, Prater, Frederic, additional, Rumfelt, Ashley, additional, Eizensmits, Christina, additional, Iannuzzi, Lisa, additional, Patel, Pourus R., additional, Bergamino, Clellia, additional, McFeaters, Elizabeth, additional, Rizk, Botros, additional, Pflaum, Emiljia, additional, Kalish, Danny, additional, Ambatali, Rex, additional, Ameli, Mona, additional, Sanguinetti, Delaina, additional, Vaidya, Rakesh, additional, Broeders, Martinus A.W., additional, Henrikus, Dorman, additional, Kuijper, Adrianus F.M., additional, Al-Windy, Nadea, additional, Magro, Michael, additional, Hamraoui, Karim, additional, Aksoy, Ismail, additional, Vermeiren, Guy L.J., additional, Roeters van Lennep, H.W.O., additional, Hoedemaker, Gerard, additional, Remmen, Johannes Jacobus, additional, Bogaard, Kjell, additional, van der Heijden, Dirk, additional, Knufman, Nicole MJ, additional, Frederiks, Joost, additional, Louwerenburg, Johannes Willem, additional, van Rossum, Piet, additional, Milhous, Johannes, additional, van der Meer, Peter, additional, van der Weerdt, Arno, additional, Breedveld, Rob, additional, Keijzers, Mitran, additional, Hermans, Walter, additional, van de Wal, Ruud, additional, Zwart, Peter A.G., additional, van der Linden, Marc M.J.M., additional, Zwiers, Gerardus, additional, Boswijk, Dirk J., additional, Geert Tans, Jan, additional, van Eck, Jacob, additional, Hessen, Maarten V., additional, Hamer, Barnabas J.B., additional, Zoet-Nugteren, Stieneke, additional, Theunissen, Lucien, additional, van Beek, E.A., additional, Nijmeijer, Remco, additional, Nierop, Pieter R., additional, Linssen, Gerard, additional, Swart, H.P., additional, Lenderink, Timo, additional, Bartels, Gerard L., additional, den Hartog, Frank, additional, Berg van den, Brian J., additional, van Kempen, Wouter, additional, Kentgens, Susanne, additional, Rojas Lingan, Gloria M., additional, Peeters, Martinus M., additional, Keterberg, Hilligje, additional, Nierman, Melchior, additional, den Hollander, Annemieke K., additional, Hoogendijk, Jacqueline, additional, Voors-Pette, Christine, additional, Kose, Vicdan, additional, Viergever, Peter, additional, Yena, Larysa, additional, Syvolap, Viktor, additional, Kopytsya, Mykola P., additional, Barna, Olga, additional, Panina, Svitlana S., additional, Lutai, Mykhailo I., additional, Shershnyova, Oxana V., additional, Luzkiv, Iryna, additional, Bula, Larysa S., additional, Zotov, Sergii, additional, Vyjhovaniuk, Ivan, additional, Lysunets, Olena, additional, Koshlia, Volodymyr I., additional, Sydor, Nataliya, additional, Vayda, Myroslava F., additional, Ushakov, Olexiy, additional, Rishko, Mykola, additional, Shcherbak, Viktor P., additional, Svyshchenko, Yevgeniya, additional, Tseluyko, Vira, additional, Yagensky, Andriy, additional, Zolotaikina, Viktoriia I., additional, Godlevska, Olga, additional, Ivanova, Larysa, additional, Koval, Olena, additional, Mitchenko, Olena I., additional, Kardash, Galyna Y., additional, Rudyk, Yurii S., additional, Stanislavchuk, Mykola, additional, Ivanovych Volkov, Volodymyr, additional, Karlinskaya, Olena G., additional, Tykhonova, Susanna A., additional, Vatutin, Nikolay, additional, Smirnova, Ganna, additional, Kovalenko, Volodymyr M., additional, Lizogub, Viktor, additional, Sebov, Denys, additional, Dyadyk, Oleksandr, additional, Andrievskaya, Svetlana, additional, Krasko, Mykola P., additional, Parkhomenko, Alexander N., additional, Horbach, Lidiya, additional, Kupnovytska, Iryna G., additional, Pertseva, Tetyana, additional, Karpenko, Oleksandr, additional, Reshotko, Dmytro, additional, Zhurba, Svitlana V., additional, Rudenko, Leonid, additional, Yu Zharinova, Viktoriia, additional, Shatylo, Valerii B., additional, Karpenko, Yuriy I., additional, Orynchak, Mariya A., additional, Kameneva, Tatiana R., additional, Zherlitsina, Elena, additional, Alpenidze, Diana N., additional, Arutyunov, Grigoriy P., additional, Baranova, Elena, additional, Bart, Boris, additional, Belenkiy, Dmitriy I., additional, Boldueva, Svetlana A., additional, Demchenko, Elena A., additional, Eltishcheva, Vera V., additional, Gofman, Alexander M., additional, Goloshchekin, Boris M., additional, Gennadyevich Gordeev, Ivan, additional, Gratsianskiy, Nikolay, additional, Kamalov, Gadel, additional, Khasanov, Niyaz R., additional, Kholina, Irina M., additional, Kobalava, Zhanna D., additional, Kobeleva, Elena V., additional, Konradi, Alexandra O., additional, Kostenko, Victor A., additional, Dmitrievich Kuimov, Andrey, additional, Ermakova, Polina Y., additional, Malyutina, Sofia K., additional, Panov, Alexey V., additional, Polezhaeva, Natalia V., additional, Reshetko, Olga, additional, Shilkina, Nataliya P., additional, Shustov, Sergey B., additional, Smolyarchuk, Elena A., additional, Stryuk, Raisa I., additional, Yurievnar Solovieva, Elena, additional, Susekov, Andrey V., additional, Vezikova, Natalia, additional, Ivanova, Svetlana N., additional, Petrov, Alexander A., additional, Konstantinov, Vladimir O., additional, Agafina, Alina S., additional, Gurevich, Victor, additional, Zrazhevskiy, Konstantin N., additional, Supryadkina, Tatiana V., additional, Perepech, Nikita B., additional, Arkhipovskiy, Vadim L., additional, Yu Butko, Dmitry, additional, Zobenko, Irina A., additional, Orlikova, Olga V., additional, Mordovin, Viktor, additional, Barbarash, Olga L., additional, Lebedeva, Anastasiya, additional, Nosov, Vladimir, additional, Averkov, Oleg V., additional, Pavlikova, Elena P., additional, Karpov, Yuri B., additional, Lvovna Giorgadze, Marina, additional, Khrustalev, Oleg A., additional, Arkhipov, Mikhail, additional, Raskina, Tatiana A., additional, Shilko, Julia V., additional, Samoilova, Yulia, additional, Kosmacheva, Elena D., additional, Nedogoda, Sergey V., additional, Coetzee, Kathleen, additional, Burgess, Lesley J., additional, Theron, F.C.R., additional, Ebrahim, Iftikhar O., additional, Haasbroek, Gerbrand A., additional, Pretorius, Maria, additional, Trokis, Julien S., additional, Urbach, Dorothea V., additional, Abelson, Mark J., additional, Horak, Adrian R., additional, Badat, Aysha E., additional, Makotoko, Ellen M., additional, Du Toit Theron, Hendrik, additional, Ramlachan, Padaruth, additional, Corbett, Clive H., additional, Mitha, Ismail H., additional, Nortje, Hendrik F.M., additional, Jansen van Rensburg, Dirkie J., additional, Sebastian, Peter J., additional, Bester, F.C.J., additional, van Zyl, Louis J., additional, Rayner, Brian L., additional, Błach, Elżbieta, additional, Dąbrowska, Magda, additional, Kania, Grzegorz, additional, Kelm-Warchol, Agata E., additional, Kinasz, Leszek P., additional, Korecki, Janusz, additional, Kruk, Mariusz, additional, Laskowska-Derlaga, Ewa, additional, Madej, Andrzej, additional, Saminski, Krzysztof, additional, Wasilewska, Katarzyna, additional, Szymkowiak, Katarzyna, additional, Wojciechowska, Małgorzata, additional, Piorowska, Natalia, additional, Dyczek, Andrzej, additional, Abhaichand, Rajpal K., additional, Byrapaneni, Ramesh B., additional, Hattur, Basavanagowdappa, additional, Bhaskara Rao, Malipeddi, additional, Ghaisas, Nitin, additional, Shankar Kadam, Sujit, additional, Gupta, Jugal B., additional, Jayadev, Santhosh M., additional, Kothiwale, V.A., additional, Mathur, Atul, additional, Bhaskar, Vijay, additional, Aluri, Ravi K., additional, Ponangi, Udaya P., additional, Sarna, Mukesh K., additional, Sathe, Sunil, additional, Sharma, Manish K., additional, Singh Sawhney, Jilendra Pal, additional, Keshavamurthy, Chakrabhavi B., additional, Srinivas, Arun, additional, Thacker, Hemant P., additional, Sharda, A., additional, Joseph, Johny, additional, Dwivedi, Sunil, additional, Mohan, Viswanathan, additional, Premchand, Rajendra K., additional, Bedard, Jacques, additional, Bergeron, Jean, additional, Collette, Ronald, additional, Crowley, David, additional, Dumas, Richard, additional, Henein, Sam, additional, Moran, Geoff, additional, O’Mahony, William F., additional, O’Mahony, Michael, additional, Chan, Sammy, additional, Sherman, Mark H., additional, Wong, Graham C., additional, Carlson, Brian D., additional, Gupta, Milan K., additional, Borts, David, additional, Peterson, Sean R., additional, Chilvers, Martyn, additional, Kelly, Allan J., additional, Gregoire, Jean C., additional, Kouz, Simon, additional, Rodés Cabau, Josep, additional, Andor, Minodora, additional, Cinteza, Mircea, additional, Ciudin, Radu, additional, Cojan, Radu I., additional, Darabont, Roxana O., additional, Dumitrascu, Dan-Lucian, additional, Fierbinteanu-Braticievici, Carmen, additional, Fruntelata, Ana Gabriela, additional, Militaru, Constantin, additional, Minescu, Bogdon E., additional, Luminita Serban, Doina, additional, Mitu, Florin, additional, Nastase Melicovici, Dorel, additional, Petrascu, Ovidiu, additional, Pirvu, Octavian M., additional, Podoleanu, Cristian, additional, Pop, Calin, additional, Stanescu-Cioranu, Rodica-Valentina V., additional, Tase, Adrian, additional, Voiculet, Cristina, additional, Aroney, Constantine N., additional, Dart, Anthony M., additional, Davis, Timothy, additional, Kostner, Karam, additional, O’Neal, David N., additional, Purnell, Peter W., additional, Singh, Bhuwanendu B., additional, Sullivan, David R., additional, Thompson, Peter, additional, Watts, Gerald F., additional, Blenkhorn, Adam F., additional, Amerena, John V., additional, Samie, Rafeeq, additional, Hendriks, Randall, additional, Proietto, Joseph, additional, Petrovsky, Nikolai, additional, Whelan, Alan, additional, Colquhoun, David, additional, Scott, Russell S., additional, Young, Simon C., additional, Pegg, Tammy, additional, Wilson, Samuel JS, additional, Hamer, Andrew W., additional, Luke, Richard A., additional, Hart, Hamish H., additional, Devlin, Gerard P., additional, Wilkins, Gerard T., additional, Ternouth, Ian F., additional, Nandra, Samraj, additional, Loeprich, Bruno S., additional, McGrath, Nicole, additional, Tie, Stuart L., additional, Bos, Rob J., additional, Wils, Alexandra, additional, Jacobs, Tamara, additional, Badings, Erik A., additional, Ebels-Tuinbeek, Lillian A., additional, Scholten, Mayke L., additional, Bayraktar-Verver, Esther, additional, Zweers, Debby, additional, Schiks, Manoek, additional, Kalkman, Carolien, additional, Tiemes, Tineke, additional, Mulderij, Jeanette, additional, Dabrowska, Katarzyna, additional, Wijnakker, Wilma, additional, Van de Loo, Riny, additional, de Graauw, Jeanne, additional, Reijnierse, Giny, additional, van der Zeijst, Mirjam, additional, Scholten, Mariska, additional, Hofmeijer, Henk R., additional, van Dijk-van der Zanden, Antoinette, additional, van Belle, Dineke J., additional, Van Es, Jan, additional, Van Buchem, Gera, additional, Zijda, Wendy, additional, Verheij, Harald, additional, Oldenhof-Janssen, Linnea, additional, Bader, Martina, additional, Löwik, Marije, additional, Stuij, Sandra, additional, Vantrimpont, Pascal, additional, van Aken, Krista, additional, Hamilton, Karen, additional, Blömer, Han, additional, van Laerhoven, Gabriela, additional, Tukkie, Raymond, additional, Janssen, Maarten, additional, Verdel, Gerard, additional, Funke Küpper, Jon, additional, van Vlies, Bob, additional, Kalkman, Caroline, additional, Vooges, Joke, additional, Vermaas, Marinella, additional, Langenberg, Rachel, additional, Haenen, Niek, additional, Smeets, Frans, additional, Scheepmaker, Arko, additional, Grosfeld, Marcel, additional, Van Lieshout, Ilvy, additional, van den Berg, Marleen, additional, Wittekoek, Marian, additional, Mol, Petra, additional, Stapel, Antionette, additional, Sierevogel, Margaretha, additional, van der Ven, Nancy, additional, Berkelmans, Annemiek, additional, Viergever, Eric, additional, Kramer, Hanneke, additional, Engelen, Wilma, additional, Houwelingen, Karen V., additional, Wildbergh, Thierry X., additional, Mosterd, Arend, additional, Hobé-Rap, Coriet, additional, van Doorn, Marjan, additional, Bunschoten, Petra, additional, Freericks, Michel, additional, Emans, Mireille, additional, Den Boer-Penning, Petra, additional, Verlek, Els, additional, Freericks, Christine, additional, de Nooijer, Cornelis, additional, Welten, Christina, additional, Groenenberg, Ingrid, additional, van der Horst, Claudia, additional, Vonk, Esther, additional, Tjeerdsma, Geert, additional, Jochemsen, Gerard M., additional, van Daalen, Corinne, additional, Danse, Ingrid Y., additional, Kuipers, Lucy, additional, Pieterse, Anke, additional, Oomen, Antonius, additional, de Waard, Daan, additional, Jan Flu, Willem, additional, Kromhout, Zusan, additional, Van der Bij, Petra, additional, Feld, Rob, additional, Hessels-Linnemeijer, Brigitta, additional, Lardinois, Rob, additional, Posma, Jan L., additional, Aukema-Wouda, Zwanette R., additional, Hendriks-van Woerden, Marjolijn, additional, van Wijk, Desiree, additional, Beelen, Driek P., additional, Hendriks, Ingrid H., additional, Jonker, Jan J., additional, Schipperen, Stefanie, additional, Köse, Vicdan, additional, Rojas, Gloria, additional, Goedhart, Linda, additional, van Meurs, Hanneke, additional, Rijssemus, Jacqueline, additional, Swinkels-Diepenmaat, Lindy, additional, de Louw-Jansen, Marloes, additional, Bierens-Peters, Dominique, additional, van Kempen, Willem W., additional, Wittekoek, Marianne E., additional, Agous, Irmaina, additional, Schenk, Geert, additional, Wittekoek, Janneke, additional, Cox, Kevin, additional, Julia, Deborah F., additional, Jonker, Jan J.C., additional, Janssen, Roel, additional, Nierman, Melchor, additional, Katerberg, Hilligje, additional, van der Haar, Irene, additional, Van Kempen, Willem W., additional, van Mesdag, Taco, additional, Alvarez Costa, Leyda M., additional, Schensema, Manon, additional, Zweekhorst, Salomé, additional, Font Julia, Deborah, additional, Hanewinckel, Lauri, additional, Olsthoorn, Joyce, additional, Berends, Johan C., additional, van der Spek, Arie C., additional, van der Berg, Roy, additional, Timmermann, Rob J., additional, Boerema, Ingrid, additional, Mudruk, Iryna, additional, Khrystoforova, Anna, additional, Kyselov, Serhii, additional, Hilova, Yaroslava V., additional, Logoida, Pavlo, additional, Sanina, Nataliia A., additional, Golikova, Ilona P., additional, Nemchyna, Olena O., additional, Isaichikov, Ivan I., additional, Potapova, Olga B., additional, Gura, Iurii V., additional, Berestetska, Larysa, additional, Kulianda, Olena O., additional, Tantsura, Oleksandr, additional, Kulbachuk, Oleksandr S., additional, Petsentiy, Volodymyr, additional, Biskub, Ihor, additional, Handych, Tetyana, additional, Lagkuti, Oleg, additional, Gagarina, Alyna, additional, Chendey, Taras, additional, Bilonko, Oksana F., additional, Matova, Olena, additional, Bezrodna, Larysa, additional, Yarynkina, Olena, additional, Ovdiienko, Tetiana, additional, Randchenko, Volodymyr, additional, Mospan, Maryna, additional, Butko, Olena, additional, Romanenko, Olga, additional, Pavelko, Mykhailo, additional, Sichkaruk, Iryna, additional, Lazareva, Svitlana O., additional, Kudryk, Olena A., additional, Koltsun, Inessa M., additional, Magdalits, Tetiana, additional, Zadorozhniy, Sergei, additional, Kompaniiets, Kira, additional, Ivanov, Andrii, additional, Romanenko, Sergiy, additional, Kaplan, Pavlo, additional, Romanov, Vadym Y., additional, Mykytyuk, Oksana P., additional, Zaitseva, Nataliia S., additional, Pyvovar, Sergiy N., additional, Burdeuna, Lyudmyla, additional, Serdobinska, Emerita, additional, Shevchenko, Tatiana I., additional, Ivanytskyi, Igor I., additional, Khyzhnyak, Olena V., additional, Kalinkina, Nataliya, additional, Keting, Olena, additional, Sklyanna, Olena, additional, Kashanska, Olga, additional, Shevelok, Anna, additional, Khristichenko, Marina, additional, Titov, Ievgenii Y., additional, Oleksander, Danilenko O., additional, Polenova, Nataliia S., additional, Altunina, Nataliia, additional, Kororaieva, Viktoriia, additional, Zborovskiy, Stanislav, additional, Kholopov, Leonid, additional, Suliman, Iurii, additional, Lukashenko, Lanna, additional, Shvaykin, Stanislav, additional, Glavatskiy, Olexandr M., additional, Sychov, Roman O., additional, Kulynych, Roman L., additional, Skarzhevskyi, Oleksandr A., additional, Dovgan, Nataliia V., additional, Horbach, Marta, additional, Cherkasova, Olga, additional, Tyshchenko, Iryna, additional, Todoriuk, Liudmyla, additional, Kizim, Svitlana, additional, Brodi, Nataliia, additional, Ivanko, Oleksandr, additional, Garbarchuk, Olga, additional, Alieksieieva, Liudmyla, additional, Shandra, Tetiana L., additional, Beregova, Olena, additional, Bodretska, Larisa An, additional, Naskalova, Svitlana S., additional, Antoniuk-Shcheglova, Ivanna A., additional, Bondarenko, Olena V., additional, Andreeva, Natalia G., additional, Vakalyuk, Iryna I., additional, Chovganyuk, Olha S., additional, Artemenko, Nataliya R., additional, Maltsev, Kiril A., additional, Kalishevich, Natalia, additional, Kondratyeva, Natalia G., additional, Nikitina, Svetlana A., additional, Martjanova, Maria V., additional, Sokolova, Anna V., additional, Dragunov, Dmitrii O., additional, Kolesnik, Olga, additional, Larina, Vera, additional, Tsygankova, Oxana V., additional, Ivanova, Maria, additional, Karpov, Illia A., additional, Aronova, Elena M., additional, Vedernikova, Ekaterina S., additional, Lubinskaya, Ekaterina I., additional, Burak, Taras Y., additional, Skichko, Sergey I., additional, Rasulev, Farhad, additional, Soldatova, Ekaterina B., additional, Fenin, Alexander L., additional, Laptev, Ilya I., additional, Luchinkina, Elena E., additional, Akatov, Alexandr, additional, Polenova, Natalia V., additional, Slavina, Natalia N., additional, Korovnika, Irina N., additional, Yu Prochorova, Marina, additional, Shakirova, Regina, additional, Andreicheva, Elena N., additional, Krasnova, Olga A., additional, Lobzhanidze, Tinatin V., additional, Dmitrova, Tatiana B., additional, Stakhiv, Viktoriya V., additional, Pechatnikova, Maria I., additional, Panova, Alexandra V., additional, Tipikina, Maria Y., additional, Rotar, Oxana P., additional, Bokovin, Nikolay A., additional, Karabalieva, Saule K., additional, Tumarov, Farid Y., additional, Vasileva, Elena V., additional, Gennadevna Lozhkina, Natalya, additional, Filippova, Ekaterina V., additional, Sharkaeva, Alisa I., additional, Filippova Deilik, Ekanerina V., additional, Yu Tolkacheva, Natalia, additional, Domracheva, Elena N., additional, Ryabikov, Andrey N., additional, Abesadze, Inga T., additional, Alugishvili, Marianna Z., additional, Nikolaeva, Elena P., additional, Smirnova, Nadezda V., additional, Rodionova, Valentina I., additional, Dolovstaya, Polina V., additional, Yunonin, Igor E., additional, Kadin, Sergey V., additional, Sveklina, Tatyana S., additional, Bushmanova, Anna V., additional, Barkova, Elena L., additional, Gomova, Irina S., additional, Brytkova, Yana V., additional, Ivanova, Tatiana B., additional, Zubareva, Marina Y., additional, Skopets, Inga, additional, Galashevskaya, Lybov A., additional, Butinskaya, Emilia D., additional, Gusarova, Olga G., additional, Kalishevich, Natalia B., additional, Pavlova, Yana R., additional, Serebrenitskaya, Marianna P, additional, Grygorieva, Vitalina F., additional, Kuchaeva, Gulnara R., additional, Vasileva, Inna A., additional, Ospanova, Gulnara I., additional, Vahrusheva, Yulia V., additional, Semenova, Irina A., additional, Mikhailova, Irina E.E., additional, Kvasova, Olga O., additional, Shurygina, Valeria D., additional, Rivin, Alexey E., additional, Savelyev, Alexey O., additional, Savelyev, Alexey A., additional, Milyaeva, Olesya O., additional, Lapshina, Nadezhda N., additional, Lantsova, Ninel A., additional, Alexandrov, Pavel V., additional, Orlikov, Evgeniy A., additional, Falkovskaya, Alla, additional, Ripp, Tatiana, additional, Triss, Sergei, additional, Pekarskiy, Stanislav, additional, Ekaterina, Sitkova, additional, Zhuravleva, Evgeniya N., additional, Perova, Olga, additional, Kovaleva, Galina, additional, Koroleva, Liubov, additional, Mishchenko, Lydia, additional, Garshin, Boris P., additional, Kutuzova, Svetlana A., additional, Provotorova, Lyudmila I., additional, Zadvorny, Igor P., additional, Okhapkina, Olga V., additional, Khrustalev, Anatoly O., additional, Suvorova, Tatiana, additional, Shaf, Elena S., additional, Vershinina, Varvara A., additional, Kozulin, Andrey A., additional, Oleynik, Oxana A., additional, Martynova, Irina Y., additional, Kizhvatova, Natalia V., additional, Salasyuk, Alla S., additional, Tsoma, Vera V., additional, Ledyaeva, Alla A., additional, Chumachek, Elena V., additional, Blignaut, S.C., additional, Alexander, Tersia Y., additional, Du Plessis, Chano, additional, Govender, Thirumani, additional, Du Toit, Samatha M., additional, Motala, Leya, additional, Gassiep, Areesh, additional, Naude (Smit), Christina, additional, Terblanche, Marli, additional, Snoer (Kruger), Marlien, additional, Pillay, Berenice, additional, Basson, De Vries, additional, Theron, Marisa E., additional, Fouche, Bianca, additional, Coetzee, Mareli E., additional, Odendall, Pieter, additional, Van Wijk, Frederik H., additional, Conradie, Anna-Mari, additional, Van der Westhuizen, Trudie, additional, Tredoux, Carine, additional, Mookdam, Mohamed S., additional, Van der Merwe, Andie J., additional, Snyman, Karin, additional, Smal, Gerda, additional, De Jager, Yvonne, additional, Mabin, Thomas A., additional, King, Annusca, additional, Henley, Lindy L., additional, Zwane, Brenda M., additional, Robinson, Jane, additional, Karsten, Marinda, additional, Page, Andonia M., additional, Nsabiyumva, Valerie, additional, Krahenbuhl, Charmaine, additional, Patel, Jaiprakash D., additional, Motala, Yunus E., additional, Dawood, Ayesha, additional, Koza, Nondumiso B., additional, Peters, Lenore M.S., additional, Ramlachan, Shavashni, additional, Bodenstein, Wilhelm J., additional, Roux, Pierre, additional, Fouche, Lizelle, additional, Boshoff, Cecilia M., additional, Mitha, Haroon M., additional, Khan, Fathima, additional, Cyster, Henry P., additional, Cyster, Helen, additional, Wessels, E. C., additional, Jacobs, Florence J., additional, Sebastian, Melanie A., additional, Sebastian, Deborah A., additional, Mahomed, Nadia, additional, Immink, Ignatius P., additional, Cotzee, Celia, additional, Cronje, Tanja, additional, Roscher, Madele, additional, Le Roux, Maria, additional, Trinder, Yvonne A., additional, Wnętrzak-Michalska, Renata, additional, Piszczek, Magdalena, additional, Piela, Andrzej, additional, Czernecka, Ewa, additional, Knychas, Dorota, additional, Walczak, Alina, additional, Gładysz, Izabella, additional, Filas, Katarzyna, additional, Kiluk, Ewelina, additional, Świgło, Krzysztof, additional, Jędrzejczyk, Iwona, additional, Łuczyńska, Kamila, additional, Tymendorf, Katarzyna, additional, Piesiewicz, Wojciech, additional, Kinasz, Wojciech L., additional, Samborski, Stefan, additional, Bartuś, Ilona, additional, Latocha Korecka, Gramzyna, additional, Gulaj, Ewa, additional, Sopa, Jolanta, additional, Derlaga, Bogusław, additional, Baisiak, Marcin, additional, Kowalisko, Allicia, additional, Stainszewska-Marasazlek, Edyta, additional, Szafran, Bartosz, additional, Swiatkiewicz, Malgorzata, additional, Racewicz, Artur, additional, Grycel, Sławomir, additional, Supronik, Jerzy, additional, Walendziuk, Sylwia, additional, Tarantowicz, Magdalena, additional, Stasiak, Agata, additional, Sidorowicz-Białynicka, Anna, additional, Dwojak, Marek, additional, Jaźwińska-Tarnawska, Ewa, additional, Kupczyk, Katarzyna, additional, Martowska, Kamila, additional, Kulon, Kamila, additional, Gajda, Katarzyna, additional, Wilson, Bivin, additional, Velusamy, Krithika, additional, Sadhiq, Swaidha S., additional, Siddeshi, Bhavani, additional, Bhanukumar, M., additional, Srivatsav, Abhishek, additional, Ramesh, Madhan, additional, Harsha Chalasani, Sri, additional, Johnson, Mini, additional, Gopu, Prashanth, additional, George, Jeesa, additional, Reddy, Sowmya, additional, Thara Eleena, Swetha Tessy, additional, Rao Kodem, Damodara, additional, Nakkella, Haritha N., additional, Kumari Mandula, Padma, additional, Kumar Vuriya, Anjan, additional, Rajana, Syamala, additional, Kale, Aruna, additional, Rajeev, Tiwari, additional, Jain, Raina, additional, Jain, Vipin, additional, Mandayam Adhyapak, Srilakshmi, additional, Sheeba, Lumin, additional, C R, Uma, additional, R, Ramya, additional, Kulkarni, Aditya V., additional, Ganachari, M.S., additional, Sambrekar, Ruma, additional, Bilal, Mohammad, additional, Chakravarthy, Kalyan, additional, Badhavath, Ravi, additional, Kumar, Sravan, additional, Simhadri, Meenakshi, additional, Salamuddin, Farooque, additional, Prasad, Venkat, additional, Dwivedi, Vivek, additional, Sarna, Sudha, additional, Arora, Tilak, additional, Chawla, Deepak, additional, Sathe, Archana, additional, Gayatree, Chaware, additional, Nanda, Ajeet, additional, Avtar, Ram, additional, Sharma, Jyoti, additional, P S, Vaibhavi, additional, D, Sasirekha, additional, Kobbajji, Deepthi, additional, Ningappa, Ramya, additional, Shree, Shwetha, additional, K, Chandrashekar, additional, M R, Nandini, additional, S, Sowjanya, additional, I G, Devika, additional, N, Yashaswini, additional, G, Sonika, additional, L, Rathna, additional, R, Priyanka, additional, Shrimanker, Rupal J., additional, Vinutha Reddy, Lakshmi, additional, Sumathi, K., additional, Devi, Babitha, additional, Naik, Bina N., additional, Manjunath, Rohini, additional, Ashok, Rajeshwari, additional, Kunjumon, Tony V., additional, Thomas, Jesline, additional, Samdhani, Shaik, additional, Selvam, Kasthuri, additional, Subramani, Poongothai, additional, Parthasarathy, Nandakumar, additional, Bohra, Nirmal K., additional, Gatla, Anvesh K., additional, Horbatuk, Cheryl, additional, Sills, Julie, additional, Davey, E B., additional, Paramonczyk, Liz, additional, Racanelli, Olga, additional, Strybosch, Sandy, additional, Belanger, Andre, additional, Palardy, Jean, additional, Schiffrin, Alicia, additional, Gauthier, Sylvie, additional, Kalyniuk, Norman, additional, Whatley, Shawn D., additional, Lappala, Heather, additional, Patel, Grishma, additional, Reeve, Matthew, additional, Moran, Catherine, additional, Everitt, Jody, additional, Ferrari, Teresa, additional, Bouffard, Christine, additional, Frohlich, Jirir, additional, Francis, Gordon, additional, Mancini, John, additional, Bondy, Gregory, additional, DeAngelis, Debbie, additional, Fulton, Patricia, additional, Blank, David W., additional, Lombardo, Angela, additional, Roy, Mylène, additional, Chow, Jackie, additional, Fox, Hyman, additional, Grootendorst, William J., additional, Hutchinson, Angela, additional, Chan, Sharon M., additional, Fitzgerald, Christie, additional, Wilkins, Lynn, additional, Raymond, Rebecca L., additional, Reyes, Arlene, additional, Marc André, Lavoie, additional, Fortin, Denis, additional, Ouimet, Hélène, additional, Tôn-Nu, Thanh-Thao, additional, Dussureault, Martine, additional, Blain, Marie-Hélène, additional, Roy, Madeleine, additional, Kopajko, Nathalie, additional, Fleury, Chantal, additional, Maheux, Karine, additional, Ciobotaru, Gabriela Valentina, additional, Constantinescu, Maria C., additional, Gherghinescu, Carmen-Lucia, additional, Avram, Ana-Maria, additional, Manitiu, Ioan, additional, Sinpetrean, Aura, additional, Pop, Lucian, additional, Lupu, Delia, additional, Usvat, Radu, additional, Petrisor, Ana, additional, Dumitru, Nicoleta, additional, Moruju, Camelia, additional, Gheorghita, Adelina, additional, Mitu, Magda V., additional, Macarie, Cosmin, additional, Pop, Ana Maria, additional, Diaconu, Maria-Catalina, additional, Grancea, Iulia, additional, Cosma, Mihaela, additional, Crisan, Mihaela, additional, Herron, Elizabeth, additional, Nestel, Paul, additional, Kay, Sally B., additional, Carter, Kaye S., additional, Badshah, Imran, additional, Makepeace, Ashley, additional, Drinkwater, Jocelyn, additional, England, Michelle, additional, Rafei, Azette, additional, Patterson, Kylie, additional, Jenkins, Alicia, additional, McAuley, Sybil, additional, Kent, Sue M., additional, Vibert, Joy E., additional, Perrett, Leonie, additional, David, Thomas, additional, Kaye, Samantha L., additional, O’Connor, Monika, additional, Perera, Nimalie J., additional, Lai, Nicole T., additional, Kearins, Kerry A., additional, Dicamillo, Christinia, additional, Anderson, Heather, additional, Ferguson, Louise, additional, Radtke, Sharon D., additional, Thamarappillil, Charles T., additional, Boys, Janice M., additional, Long, Anita K., additional, Shanahan, Toni, additional, Nyguyen, Michael, additional, Forrest, Nicole, additional, Tulloch, Gill, additional, Greenwell, Della, additional, Price, Sarah L., additional, Tint, Aye N., additional, Sumithran, Priya K., additional, Debreceni, Tamara L., additional, Walker, Lisa, additional, Caruana, Mary, additional, Edwards, Kira, additional, Stathopoulos, Maria, additional, Haywood, Cilla, additional, Sajkov, Dimitar, additional, Pringle, Sharen, additional, Tabner, Anne, additional, Bartolay, Kathrina, additional, Abeyratne, Chamindi, additional, Bragg, Kylie, additional, Mulhern, Patrick, additional, Purnell, Peter, additional, Williams, Lyn, additional, Hamlyn, Jane, additional, Connelly, Aurelia, additional, Hoffman, Jan, additional, Bailey, Samantha, additional, Kerr, Jane, additional, Morrison, Zarnia, additional, Maeder, Sarah, additional, McEwan, Roberta, additional, Kunasekera, Prasanna, additional, McGregor, Patrice, additional, Young, Jo, additional, Berry, Sharon, additional, Cutfield, Rick, additional, Choe, Michelle, additional, McNamara, Catherine, additional, Shergill, Narrinder K., additional, Crone, Petra, additional, Williams, Miles G., additional, Dyson, Keith, additional, Schmid, Diana H., additional, Doak, Audrey C., additional, Spooner, Melissa, additional, Edwards, Colin, additional, Turner, Anne, additional, McAnnalley, Grainne M., additional, Fisher, Raewyn A., additional, Hamilton, Fraser B., additional, Friedlander, Denis H., additional, Kirk, Melissa R., additional, Scales, Jayne E., additional, McLelland, Marguerite A., additional, Dalman, Neelam A., additional, Vickers, Cathy E., additional, Jackson, Carolyn, additional, Coleman, Wendy, additional, Garden, Phillip I., additional, and Arnold, Wendy F., additional
Published: 2021
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3. Increased risk of lipodystrophy when nucleoside analogue reverse transcriptase inhibitors are included with protease inhibitors in the treatment of HIV-1 infection

Author: Ferdinand W. N. M. Wit, Elisabeth H. Gisolf, A. Japour, G. J. Weverling, Peter Reiss, M. van der Valk, S. A. Danner, Internal medicine, Other departments, Amsterdam institute for Infection and Immunity, and Global Health
Subjects: medicine.medical_specialty, Time Factors, Lipodystrophy, Anti-HIV Agents, Immunology, HIV Infections, Gastroenterology, law.invention, Randomized controlled trial, Risk Factors, law, Internal medicine, medicine, Humans, Immunology and Allergy, Protease inhibitor (pharmacology), Adverse effect, Saquinavir, Ritonavir, Nucleoside analogue, business.industry, Stavudine, HIV Protease Inhibitors, medicine.disease, CD4 Lymphocyte Count, Infectious Diseases, HIV-1, RNA, Viral, Reverse Transcriptase Inhibitors, Drug Therapy, Combination, business, Follow-Up Studies, medicine.drug
Abstract: Background: Changes in body fat distribution are an adverse effect of therapy with HIV protease inhibitors (PI). It has been suggested that nucleoside analogue reverse transcriptase inhibitors (NRTI) may also contribute to this so-called lipodystrophy syndrome, but the relative contribution of the two drug classes is unclear as they are usually administered concomitantly. Method: The occurrence of lipodystrophy, as reported by physicians using no standardized criteria, was followed in patients randomly assigned to treatment with either a PI alone or a PI combined with an NRTI. The patients were part of a multicenter, open-label, randomized comparison of ritonavir (RTV)/saquinavir (SQV) with or without the addition of stavudine (d4T) in HIV-1-infected patients without prior PI and d4T experience (the Prometheus study). Results: Lipodystrophy was reported in 29 of 175 (17%) patients during 96 weeks of follow up. Overall, it was reported significantly more frequently in patients who were randomized to RTV/SQV/d4T (22/88; 25%), than in patients randomized to RTV/SQV alone (7/87; 8%) (P = 0.003). When the analysis was limited to patients without any prior antiretroviral experience, lipodystrophy likewise was significantly more frequent in patients randomized to RTV/SQV/d4T (12/50; 24%) than in those randomized to RTV/SQV (2/44; 5%) (P = 0.008). Conclusion: This randomized clinical trial, in spite of not having been blinded, supports a contributory role of NRTI in the development of antiretroviral therapy-associated lipodystrophy. The low incidence of lipodystrophy in patients with no or limited NRTI exposure supports further evaluation of NRTI-sparing regimens as alternatives to current antiretroviral regimens.
Published: 2001

4. HIV-1 genotypic zidovudine drug resistance and the risk of maternal–infant transmission in the Women and Infants Transmission Study*

Author: Robert C. Colgrove, Anthony J. Japour, Mary Glenn Fowler, Shahin Lockman, John Moye, Amy E. Colson, Sheldon Landesman, Pei Hua Chung, Celine Hanson, Seth L. Welles, Kenneth C. Rich, Kenneth McIntosh, Jane Pitt, and Carmen D. Zorrilla
Subjects: Pregnancy, medicine.medical_specialty, Maternal Transmission, Immunology, virus diseases, Drug resistance, Odds ratio, Biology, medicine.disease, Resistance mutation, Zidovudine, Infectious Diseases, Internal medicine, medicine, Immunology and Allergy, Risk factor, Viral load, medicine.drug
Abstract: Objectives: Although the treatment of pregnant women and their infants with zidovudine (ZDV) has been remarkably effective in preventing the perinatal transmission of human HIV-1, many potentially preventable infections still occur. To examine whether the risk of perinatal infection is increased among women who carry ZDV-resistant HIV-1, the role of genotypic ZDV resistance in perinatal transmission was evaluated. Methods: The reverse transcriptase (RT) region of clinical isolates from culture supernatants of 142 HIV-1 -infected women enrolled in the Women and Infants Transmission Study (WITS), who had been treated with ZDV during pregnancy was sequenced. Results from genotypic sequencing were linked to demographic, laboratory, and obstetrical databases, and the magnitude of association of having consensus drug-resistant HIV-1 RT mutations with transmission was estimated. Results: Twenty-five per cent (34/142) of maternal isolates had at least one ZDV-associated resistance mutation. A lower CD4 cell percentage and count (P = 0.0001) and higher plasma HIV-1 RNA (P = 0.006) were associated with having any ZDV resistance mutation at delivery. Having any RT resistance mutation [odds ratio (OR): 5.16; 95% confidence interval (CI): 1.40, 18.97; P = 0 0.01], duration of ruptured membranes [OR: 1.13 (1.02, 1.26) per 4 h duration; P= 0.02], and total lymphocyte count [OR: 1.06 (1.01, 1.10) per 50 cells higher level; P = 0.009] were independently associated with transmission in multivariate analysis. Conclusion: Maternal ZDV resistant virus was predictive of transmission, independent of viral load, in these mothers with moderately advanced HIV-1 disease, many of whom had been treated with ZDV before pregnancy.
Published: 2000

5. HIV protease inhibitors

Author: Akhteruzzaman Molla and Anthony J. Japour
Subjects: Microbiology (medical), Infectious Diseases, business.industry, HIV Protease Inhibitor, Medicine, business, Virology
Published: 1997

6. A Phase-I Study of the Safety, Pharmacokinetics, and Antiviral Activity of Combination Didanosine and Ribavirin in Patients with HIV-1 Disease

Author: S. Hussey, Elizabeth L. Cooney, Clyde S. Crumpacker, Kenneth Wood, Pamela A. Clax, Richard B. Pollard, Yannis Bassiakos, Brigitte P. Griffith, Patricia M. Meehan, Mary Walesky, David K. Booth, Colin McLaren, Joseph Timpone, Nils Johanneson, Juan J.L. Lertora, James D. Connor, Alejo Erice, Anthony J. Japour, and Jeanne Holden-Wiltse
Subjects: Chemotherapy, medicine.medical_specialty, business.industry, medicine.medical_treatment, Ribavirin, Immunology, virus diseases, Gastroenterology, Titer, Regimen, chemistry.chemical_compound, Pharmacotherapy, chemistry, Pharmacokinetics, Virology, Internal medicine, medicine, Immunology and Allergy, Adverse effect, business, Didanosine, medicine.drug
Abstract: A phase-I study was conducted to examine the safety, pharmacokinetics, and activity of combination 2',3'-dideoxyinosine (ddI) and ribavirin against human immunodeficiency virus type 1 (HIV-1)-positive individuals with CD4+ cell counts of < or = 500/microliter. Nineteen patients were enrolled into the study in which ddI monotherapy (200 mg p.o.b.i.d.) was administered for the first 4 weeks, followed by the coadministration of ribavirin (600 mg p.o.q.d.) and ddI (200 mg p.o.b.i.d.) for 8 or 20 additional weeks. The combination regimen was safe and well tolerated. Three patients did not complete 12 weeks of the study because of adverse events or voluntary withdrawal. The pharmacokinetic studies performed at weeks 4, 6, and 12 on specimens collected from the 15 individuals who completed 12 weeks of therapy revealed no pharmacokinetic interaction between ddI and ribavirin. A significant decline from baseline in HIV-1 titer as measured by quantitative HIV-1 culture was detected both during the ddI-monotherapy phase (week 4, p < 0.001) and during the combination-therapy ddI + ribavirin phase (week 12, p < 0.001); the median drop observed was 0.90 log10 at week 4 and 0.92 log10 at week 12. While the addition of ribavirin did not result in further reductions in viremia in the following weeks on study treatment, 13 (81%) of the 16 patients had at least a -0.5 log10 change in viral titer at week 12. The median decline in plasma viral RNA was 0.68 log10 at week 4(p < 0.001) and 0.67 log10 at week 12 (p = 0.005). CD4+ cell counts increased above baseline significantly during the ddI-monotherapy phase of the study (p = 0.0038). The median increase was +26 cells/mm3 at week 4 and +11 cells/mm3 at week 12; for patients who remained on treatment through 24 weeks, the median CD4+ cell count increase was +10 cells/mm3. The L74V ddI resistance-conferring HIV-I reverse-transcriptase mutation emerged in 53% of the patients. Patients with non-syncytium-inducing HIV variants demonstrated greater responses to treatment with larger decreases in virus load and greater increases in CD4+ cell count. Our results reveal that the combination of ddI and ribavirin in HIV-positive patients is safe, well tolerated, without adverse pharmacologic interaction, and associated with significant and sustained declines in virus load over 12 weeks of therapy.
Published: 1996

7. Increased risk of lipodystrophy when nucleoside analogue reverse transcriptase inhibitors are included with protease inhibitors in the treatment of HIV-1 infection

Author: van der Valk, M., primary, Gisolf, E. H., additional, Reiss, P., additional, Wit, F. W. N. M., additional, Japour, A., additional, Weverling, G. J., additional, and Danner, S. A., additional
Published: 2001
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8. ABT-378/ritonavir plus stavudine and lamivudine for the treatment of antiretroviral-naive adults with HIV-1 infection: 48-week results

Author: Murphy, Robert L., primary, Brun, Scott, additional, Hicks, Charles, additional, Eron, Joseph J., additional, Gulick, Roy, additional, King, Martin, additional, White, A. Clinton, additional, Benson, Constance, additional, Thompson, Melanie, additional, Kessler, Harold A., additional, Hammer, Scott, additional, Bertz, Richard, additional, Hsu, Ann, additional, Japour, Anthony, additional, and Sun, Eugene, additional
Published: 2001
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9. The effect of treatment intensification in HIV-infection: a study comparing treatment with ritonavir/saquinavir and ritonavir/saquinavir/stavudine

Author: Gisolf, Elisabeth H., primary, Jurriaans, Suzanne, additional, Pelgrom, Jolanda, additional, van Wanzeele, Filip, additional, van der Ende, Marchina E., additional, Brinkman, Kees, additional, Borst, Marie-José, additional, de Wolf, Frank, additional, Japour, Anthony J., additional, and Danner, Sven A., additional
Published: 2000
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10. HIV-1 genotypic zidovudine drug resistance and the risk of maternal–infant transmission in the Women and Infants Transmission Study*

Author: Welles, Seth L., primary, Pitt, Jane, additional, Colgrove, Robert, additional, McIntosh, Kenneth, additional, Chung, Pei Hua, additional, Colson, Amy, additional, Lockman, Shahin, additional, Fowler, Mary Glenn, additional, Hanson, Celine, additional, Landesman, Sheldon, additional, Moye, John, additional, Rich, Kenneth C., additional, Zorrilla, Carmen, additional, and Japour, Anthony J., additional
Published: 2000
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11. Ritonavir and saquinavir combination therapy for the treatment of HIV infection

Author: Cameron, William, primary, Japour, Anthony J., additional, Xu, Yi, additional, Hsu, Ann, additional, Mellors, John, additional, Farthing, Charles, additional, Cohen, Calvin, additional, Poretz, Donald, additional, Markowitz, Martin, additional, Follansbee, Steve, additional, Angel, Jonathan B., additional, McMahon, Deborah, additional, Ho, David, additional, Devanarayan, Viswanath, additional, Rode, Richard, additional, Salgo, Miklos P., additional, Kempf, Dale J., additional, Granneman, Richard, additional, Leonard, John M., additional, and Sun, Eugene, additional
Published: 1999
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12. Selective vertical transmission of HIV-1 antiretroviral resistance mutations

Author: Colgrove, Robert C., primary, Pitt, Jane, additional, Hua Chung, Pei, additional, Welles, Seth L., additional, and Japour, Anthony J., additional
Published: 1998
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13. The duration of viral suppression during protease inhibitor therapy for HIV-1 infection is predicted by plasma HIV-1 RNA at the nadir

Author: Kempf, Dale J., primary, Rode, Richard A., additional, Xu, Yi, additional, Sun, Eugene, additional, Heath-Chiozzi, Margo E., additional, Valdes, Joaquin, additional, Japour, Anthony J., additional, Danner, Sven, additional, Boucher, Charles, additional, Molla, Akhteruzzaman, additional, and Leonard, John M., additional
Published: 1998
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14. HIV protease inhibitors

Author: Molla, Akhteruzzaman, primary and Japour, Anthony, additional
Published: 1997
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14 results on '"Japour A"'

1. Icosapent Ethyl Reduces Ischemic Events in Patients With a History of Previous Coronary Artery Bypass Grafting: REDUCE-IT CABG

2. Icosapent Ethyl Reduces Ischemic Events in Patients With a History of Previous Coronary Artery Bypass Grafting: REDUCE-IT CABG

3. Increased risk of lipodystrophy when nucleoside analogue reverse transcriptase inhibitors are included with protease inhibitors in the treatment of HIV-1 infection

4. HIV-1 genotypic zidovudine drug resistance and the risk of maternal–infant transmission in the Women and Infants Transmission Study*

5. HIV protease inhibitors

6. A Phase-I Study of the Safety, Pharmacokinetics, and Antiviral Activity of Combination Didanosine and Ribavirin in Patients with HIV-1 Disease

7. Increased risk of lipodystrophy when nucleoside analogue reverse transcriptase inhibitors are included with protease inhibitors in the treatment of HIV-1 infection

8. ABT-378/ritonavir plus stavudine and lamivudine for the treatment of antiretroviral-naive adults with HIV-1 infection: 48-week results

9. The effect of treatment intensification in HIV-infection: a study comparing treatment with ritonavir/saquinavir and ritonavir/saquinavir/stavudine

10. HIV-1 genotypic zidovudine drug resistance and the risk of maternal–infant transmission in the Women and Infants Transmission Study*

11. Ritonavir and saquinavir combination therapy for the treatment of HIV infection

12. Selective vertical transmission of HIV-1 antiretroviral resistance mutations

13. The duration of viral suppression during protease inhibitor therapy for HIV-1 infection is predicted by plasma HIV-1 RNA at the nadir

14. HIV protease inhibitors

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14 results on '"Japour A"'

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