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2 results on '"Itai Bab"'

1. Capsule Around Silicone Implants in Diabetic Rats

Author

Shlomo Ticher, Menachem R. Wexler, Shefi Ben Moshe, Isaac J. Peled, Dan Gazit, Itai Bab, and Shmuel Shoshan

Subjects
Blood Glucose, medicine.medical_specialty, Fibrous capsule, Diabetes Mellitus, Experimental, chemistry.chemical_compound, Silicone, Internal medicine, Diabetes mellitus, medicine, Animals, Breast, Dimethylpolysiloxanes, Skin, Glucose tolerance test, medicine.diagnostic_test, business.industry, Capsule, Histology, Prostheses and Implants, Glucose Tolerance Test, medicine.disease, Prosthesis Failure, Rats, Disease Models, Animal, Endocrinology, chemistry, Silicone Elastomers, Surgery, Implant, business, Type I collagen
Abstract

Polydimethylsiloxane (silicone) implants were subcutaneously placed in the back of diabetic and normal rats. After three months the rats were killed and the fibrous capsule around the implants was histologically and biochemically examined. A significant quantitative difference (p less than 0.001) was found in the thickness of the capsules, which were two to three times thicker in the diabetic animals. The biochemistry showed an increase of neutral salt-soluble collagen in the diabetic group; electrophoresis revealed only type I collagen in the diabetic and type I and III in the normal rats. From this experimental trial it seems that diabetes mellitus is another factor in formation of a thick capsule around silicone implants.

Published
1986

2. Histomorphometric Evaluation of Reversible Heparin-Induced Osteoporosis in Pregnancy

Author

Ari Zimran, Drora Fisher, Shmuel Shilo, and Itai Bab

Subjects
Adult, medicine.medical_specialty, Bone disease, Osteoporosis, Urology, Pregnancy, Internal Medicine, medicine, Humans, Stage (cooking), Heparin therapy, Heparin, business.industry, Obstetrics and Gynecology, General Medicine, medicine.disease, Surgery, Discontinuation, Pregnancy Complications, Osteopenia, Female, business, medicine.drug
Abstract

• Transilial bone biopsy confirmed heparin-induced osteopenia in a 23-year-old postpartum patient. Histomorphometric measurements during the reversible stage of bone disease that followed discontinuation of the heparin sodium therapy revealed signs of recovery; these were superimposed on a loose trabecular structure typical of osteoporosis. The histomorphometric evidence of recovery correlated well with signs of clinical improvement. In the majority of patients, heparin therapy during pregnancy is innocuous; however, discontinuation of treatment is recommended at the earliest signs of osteoporosis. ( Arch Intern Med 1986;146:386-388)

Published
1986

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