1. Copeptin levels predict left ventricular systolic function in STEMI patients
- Author
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Engin Algül, Faruk Aydınyılmaz, İlkin Guliyev, Ali Nallbani, Haluk Furkan Şahan, Hilal Erken Pamukcu, Mehmet Ali Felekoğlu, Nail Burak Özbeyaz, and Saadet Demirtas Inci
- Subjects
Male ,medicine.medical_specialty ,Longitudinal strain ,Observational Study ,Systolic function ,Ventricular Dysfunction, Left ,03 medical and health sciences ,0302 clinical medicine ,Copeptin ,Predictive Value of Tests ,Internal medicine ,2d speckle tracking ,medicine ,Humans ,Prospective Studies ,030212 general & internal medicine ,Myocardial infarction ,business.industry ,Glycopeptides ,copeptin ,General Medicine ,Middle Aged ,medicine.disease ,ST-segment elevation myocardial infarction ,medicine.anatomical_structure ,Echocardiography ,Ventricle ,030220 oncology & carcinogenesis ,Cardiology ,ST Elevation Myocardial Infarction ,Population study ,Female ,Observational study ,business ,Biomarkers ,global longitudinal strain ,Research Article - Abstract
In the present study, we aimed to investigate whether copeptin values on admission are related to left ventricle (LV) systolic function and its improvement at 6 months in ST-segment elevation myocardial infarction (STEMI) patients. In this single-center, prospective observational study, we included 122 STEMI patients from January 2016 to November 2016. LV systolic functions in the form of global longitudinal strain (GLS) in addition to conventional echocardiography parameters were evaluated on admission and at 6-month. Serum copeptin levels were determined using an ultrasensitive immunofluorescence assay. The study population was divided into 2 groups according to median values of copeptin. GLS was significantly lower in patients with high copeptin levels compared to those with low copeptin levels at early stage and 6-month (−16% (16–16.5) vs −15% (15–15.5), P
- Published
- 2020
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