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Your search keyword '"A. Serdarevic"' showing total 23 results
Start Over Author "A. Serdarevic" Publisher ovid technologies (wolters kluwer health)
23 results on '"A. Serdarevic"'

2. Effects of Ciprofloxacin, Streptomycin, and Gentamicin on Rabbit Corneal Transendothelial Electrical Potential Difference

Author

Zhaorong Zhu, Fengying Kang, Jun Li, Jorge Fischbarg, Olivia N. Serdarevic, and Kunyan Kuang

Subjects
Corneal endothelium, medicine.drug_class, medicine.medical_treatment, Antibiotics, Pharmacology, Membrane Potentials, Microbiology, Anti-Infective Agents, Ciprofloxacin, medicine, Animals, Saline, Corneal Decompensation, Chemistry, Endothelium, Corneal, Electric Conductivity, Biological Transport, biochemical phenomena, metabolism, and nutrition, Anti-Bacterial Agents, Ophthalmology, Streptomycin, Rabbit model, Gentamicin, Rabbits, Gentamicins, medicine.drug
Abstract

PURPOSE A previous report suggested that high concentrations of ciprofloxacin in the anterior chamber may cause dose-dependent acute corneal decompensation. Therefore we evaluated the effect of varying concentrations of ciprofloxacin in the anterior chamber on the corneal endothelium and compared these effects with those of gentamicin and streptomycin. METHODS We assessed endothelial transport function by determining transendothelial electrical potential differences (TEPDs) of rabbit corneas. Our control solution was bicarbonate-buffered balanced saline with glucose (BSG), to which we added ciprofloxacin (50, 100, 125, and 150 microg/ml), gentamicin (1,000 and 2,000 microg/ml), and streptomycin (196, 437, and 696 microg/ml). RESULTS At high concentrations exceeding minimal inhibitory concentrations against 90% of common ocular isolates (MIC90), accelerated decay of TEPDs was seen with all three antibiotics. Adverse effects on TEPDs were noted at concentrations corresponding to >50 times MICs with ciprofloxacin and 40 x MICs with gentamicin, but only 2 times MICs with streptomycin. CONCLUSION Our study shows that concentrations of ciprofloxacin, gentamicin, and streptomycin below or equal to their MIC90 levels do not adversely affect endothelial transport function in a rabbit model.

Published
1998
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4. Anesthesiology to Rescue

Author

Mirsad Serdarevic

Subjects
medicine.medical_specialty, Anesthesiology and Pain Medicine, business.industry, Anesthesiology, Medicine, Medical emergency, business, medicine.disease
Published
2013
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5. A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study of Oral Sildenafil Citrate in Treatment-Naive Children With Pulmonary Arterial Hypertension

Author

Barst, Robyn J., primary, Ivy, D. Dunbar, additional, Gaitan, Guillermo, additional, Szatmari, Andras, additional, Rudzinski, Andrzej, additional, Garcia, Alberto E., additional, Sastry, B.K.S., additional, Pulido, Tomas, additional, Layton, Gary R., additional, Serdarevic-Pehar, Marjana, additional, and Wessel, David L., additional

Published
2012
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23. CIRCULAR KERATOTOMY BY EXCIMER LASER

Author

Pouliquen Y, M. Savoldelli, O Serdarevic, de Gribomont, and Hanna K

Subjects
Ophthalmology, Optics, Excimer laser, business.industry, medicine.medical_treatment, Medicine, business
Published
1989
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