1. Incidence of Thyroid Dysfunction & its Co-relation with Diabetic Retinopathy.
- Author
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Obaid, Naila, Asghar, Asfandyar, Rizwan, Amna, Khan, Sumayya Ali, and Naeem, B. A.
- Subjects
THYROID diseases ,DIABETIC retinopathy ,DISEASE incidence ,GLYCOSYLATED hemoglobin ,THYROXINE ,THYROTROPIN - Abstract
Objective: To evaluate the incidence of thyroid dysfunction in patients with Diabetic Retinopathy and see the correlation with stage of diabetic retinopathy. It was a cross sectional descriptive study in the Department of Ophthalmology, Fauji Foundation Hospital, Rawalpindi. Methods: This study was conducted in Department of Ophthalmology, Fauji Foundation Hospital, Rawalpindi, from 1
st September 2016 to 30th March 2017. All the cases of Diabetic Retinopathy were included except those who lost follow up. A detailed history with complete ocular was carried out All the patients were investigated for Glycosylated Hemoglobin (HbA1c), total tri-iodo--thyronine (T3), total thyroxine (T4), and thyroid stimulating hormone (TSH). Results: A total number of 82 patients with non-proliferative and proliferative diabetic retinopathy were studied. There were 27 patients of proliferative Diabetic Retinopathy (PDR) (32.9%) and 55 patients of non-proliferative Diabetic Retinopathy (NPDR) (67%). 25 patients out of total 82 patients had deranged thyroid hormone and TSH levels (30.48%). Among these 25 cases, 13 cases had hypothyroidism, 6 cases had hyperthyroidism and 6 had low T3 syndrome (15.8 %, 7.3 % and 7.3 % respectively). Out of total 27 cases of PDR; 8 cases had hypothyroidism, 6 has hyperthyroidism and 2 had low T3 syndrome ( 29.6%, 22.2 % and 7.4% respectively). While in NPDR group, out of total 55 patients 5 had hypothyroidism (9.09%), 4 patients had low T3 syndrome (7.27%) and none of the patients had hyperthyroidism. Conclusion: Thyroid dysfunction is found in significant number of patients with diabetic retinopathy. Thyroid function tests are more deranged in patients with proliferative diabetic retinopathy than non-proliferative diabetic retinopathy. Thyroid dysfunction may be another risk factor for progression of diabetic retinopathy, hence the thyroid screening in type 2 diabetic patients can favor better management of patients and prevent sight threatening complications of diabetic retinopathy. [ABSTRACT FROM AUTHOR]- Published
- 2018